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Journal of Biological Chemistry, ISSN 0021-9258, 03/2004, Volume 279, Issue 11, pp. 10784 - 10795
The source of NADPH-dependent cytosolic 3beta-hydroxysteroid dehydrogenase (3beta-HSD) activity is unknown to date. This important reaction leads e. g. to the... 
HYDROXYSTEROID DEHYDROGENASES | SUBSTRATE-SPECIFICITY | HUMAN 20-ALPHA-HYDROXYSTEROID DEHYDROGENASE | HUMAN PROSTATE | HUMAN BRAIN | MALE RATS | ANDROGEN METABOLISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROACTIVE STEROIDS | SITE-DIRECTED MUTAGENESIS | DIHYDRODIOL DEHYDROGENASE
Journal Article
Steroids, ISSN 0039-128X, 2004, Volume 69, Issue 13, pp. 795 - 801
Journal Article
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 2006, Volume 248, Issue 1, pp. 126 - 135
Endometrial cancer is the most common malignancy of the female genital tract. Its incidence correlates with prolonged estrogen stimulation unopposed by... 
Short-chain dehydrogenase reductase | 17β-Hydroxysteroid dehydrogenase | 20α-Hydroxysteroid dehydrogenase | Aldo-keto reductase | 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE-2 | HYDROXYSTEROID DEHYDROGENASES | ER-BETA | short-chain dehydrogenase reductase | RECEPTOR-B | CELL BIOLOGY | INACTIVATION | CARCINOGENESIS | KETO REDUCTASE SUPERFAMILY | ENDOCRINOLOGY & METABOLISM | 20 alpha-hydroxysteroid dehydrogenase | aldo-keto reductase | 17 beta-hydroxysteroid dehydrogenase | EXPRESSION | CARCINOMA | HORMONES | Humans | Endometrial Neoplasms - metabolism | Hydroxyprostaglandin Dehydrogenases - metabolism | Estrogens - analysis | Endometrial Neoplasms - genetics | Isoenzymes - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Female | Progesterone - biosynthesis | Tumor Cells, Cultured | Estradiol - biosynthesis | Endometrium - metabolism | Progesterone - analysis | 20-Hydroxysteroid Dehydrogenases - genetics | Estrogens - biosynthesis | Endometrial Neoplasms - chemistry | Oxidoreductases - metabolism | Isoenzymes - genetics | 20-Hydroxysteroid Dehydrogenases - metabolism | Hydroxyprostaglandin Dehydrogenases - genetics | Endometrium - chemistry | Animals | Aldo-Keto Reductase Family 1 Member C3 | Estradiol Dehydrogenases | 3-Hydroxysteroid Dehydrogenases - genetics | 17-Hydroxysteroid Dehydrogenases - metabolism | Enzymes | Care and treatment | Endometrial cancer | Phenols | Hormones | Progesterone | Estradiol | Cancer | Index Medicus
Journal Article
Journal Article
Oncology Reports, ISSN 1021-335X, 03/2017, Volume 37, Issue 4, pp. 2025 - 2032
Resistance to anticancer medications often leads to poor outcomes. The present study explored an effective approach for enhancing chemotherapy targeted against... 
aldo-keto reductase | cisplatin | mefenamic acid | 5-FU | Cisplatin, 5-FU | Mefenamic acid | Aldo-keto reductase | HUMAN OVARIAN | AKR1C3 | CISPLATIN RESISTANCE | TUMOR-CELLS | CHEMOTHERAPY | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE | LUNG-CANCER | CARCINOMA CELL-LINE | ONCOLOGY | SUPERFAMILY | EXPRESSION | 20-Hydroxysteroid Dehydrogenases - biosynthesis | 3-Hydroxysteroid Dehydrogenases - biosynthesis | 20-Hydroxysteroid Dehydrogenases - genetics | Humans | Hydroxyprostaglandin Dehydrogenases - biosynthesis | Hydroxysteroid Dehydrogenases - genetics | Hydroxyprostaglandin Dehydrogenases - genetics | Cisplatin - administration & dosage | Neoplasms - drug therapy | 3-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Hydroxyprostaglandin Dehydrogenases - antagonists & inhibitors | Fluorouracil - administration & dosage | 20-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Neoplasms - genetics | Aldo-Keto Reductase Family 1 Member C3 | Mefenamic Acid - administration & dosage | Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Hydroxysteroid Dehydrogenases - biosynthesis | Gene Expression Regulation, Neoplastic - drug effects | HeLa Cells | Oxidoreductases | 3-Hydroxysteroid Dehydrogenases - genetics | Neoplasms - pathology | Drug Resistance, Neoplasm - drug effects | Care and treatment | Patient outcomes | Genetic aspects | Drug resistance | Gene expression | Health aspects | Methods | Cancer | Studies | Enzymes | Oxidative stress | Chemotherapy | Genes | Rodents | Prostate | Experiments | Cancer therapies | Deoxyribonucleic acid--DNA | Apoptosis | Index Medicus
Journal Article
Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 2011, Volume 125, Issue 1, pp. 148 - 161
Journal Article
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 02/2009, Volume 296, Issue 2, pp. 244 - 255
The objective was to examine pathways of androgen metabolism in abdominal adipose tissue in women. Abdominal subcutaneous (SC) and omental (OM) adipose tissue... 
Omental visceral fat | Adipocyte differentiation | Short-chain dehydrogenases | Aldo-keto reductases | Estrogen | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASES | AROMATASE-ACTIVITY | estrogen | PHYSIOLOGY | short-chain dehydrogenases | adipocyte differentiation | omental visceral fat | HUMAN PREADIPOCYTES | 20-ALPHA-HYDROXYSTEROID DEHYDROGENASE | ESTROGEN-RECEPTOR-BETA | OBESITY | 17-BETA-HYDROXYSTEROID-DEHYDROGENASE | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | aldo-keto reductases | DIFFERENTIATION | STROMAL CELLS | Adipose Tissue - physiology | Humans | Middle Aged | Gene Expression Regulation, Enzymologic - physiology | Hydroxyprostaglandin Dehydrogenases - metabolism | Adipogenesis - physiology | Adipose Tissue - metabolism | Subcutaneous Fat - metabolism | Omentum - enzymology | 3-Hydroxysteroid Dehydrogenases - metabolism | Adult | Female | Hydroxysteroid Dehydrogenases - metabolism | Metabolic Networks and Pathways - physiology | Body Fat Distribution | Adipogenesis - genetics | Cells, Cultured | Hydroxysteroid Dehydrogenases - genetics | Omentum - metabolism | Hydroxyprostaglandin Dehydrogenases - genetics | Abdominal Fat - metabolism | Metabolic Networks and Pathways - genetics | Aldo-Keto Reductase Family 1 Member C3 | Estradiol Dehydrogenases | Models, Biological | 17-Hydroxysteroid Dehydrogenases - genetics | Abdominal Fat - enzymology | Adipose Tissue - enzymology | 3-Hydroxysteroid Dehydrogenases - genetics | Androgens - metabolism | 17-Hydroxysteroid Dehydrogenases - metabolism | Subcutaneous Fat - enzymology | Women | Tissue | Enzymes | Androgens | Body fat | Metabolism | Ribonucleic acid--RNA | Index Medicus
Journal Article
The FEBS Journal, ISSN 1742-464X, 11/2018, Volume 285, Issue 21, pp. 3993 - 4004
Journal Article
PHYSIOLOGICAL REVIEWS, ISSN 0031-9333, 07/2013, Volume 93, Issue 3, pp. 1139 - 1206
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 03/2016, Volume 472, Issue 1, pp. 231 - 236
Journal Article