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Journal Article
Molecular Cell, ISSN 1097-2765, 06/2015, Volume 58, Issue 5, pp. 832 - 844
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2018, Volume 13, Issue 10, pp. e0205870 - e0205870
In eukaryotes, the modification of an invariant histidine (His-699 in yeast) residue in translation elongation factor 2 (EF2) with diphthamide involves a... 
MOUSE DEVELOPMENT | ANTICODON LOOP MODIFICATIONS | ADP-RIBOSYLATING TOXINS | TRANSFER-RNA MODIFICATION | BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES | KLUYVEROMYCES-LACTIS ZYMOCIN | SACCHAROMYCES-CEREVISIAE | DIPHTHERIA-TOXIN | PROTEIN-SYNTHESIS | ELONGATION-FACTOR 2 | Histidine - analogs & derivatives | Saccharomyces cerevisiae - genetics | Methyltransferases - metabolism | Methyltransferases - genetics | Saccharomyces cerevisiae - drug effects | Diphtheria Toxin - toxicity | Histidine - metabolism | Saccharomyces cerevisiae - metabolism | Peptide Elongation Factor 2 - genetics | Hygromycin B - pharmacology | Gene Deletion | Caffeine - pharmacology | Peptide Elongation Factor 1 - genetics | Hygromycin B - analogs & derivatives | Gene Expression Regulation, Fungal | Histidine - genetics | Saccharomyces cerevisiae Proteins - genetics | Cinnamates - pharmacology | Sirolimus - pharmacology | Cell Division - drug effects | Phenotype | Peptide Elongation Factor 2 - deficiency | Saccharomyces cerevisiae Proteins - metabolism | Anisomycin - pharmacology | Protein Biosynthesis - drug effects | Peptide Elongation Factor 1 - metabolism | Saccharomyces cerevisiae - growth & development | Amino Acid Substitution | Research | Yeast fungi | Growth | Genetic translation | Imidazole | Cells | Yeast | Growth rate | Genes | Cytotoxicity | Translocase | mRNA | Biosynthesis | Saccharomyces | ADP | Defects | Proteins | Eukaryotes | Cell growth | Histidine | Translation elongation factor 2 | Diphtheria toxin | Elongation | Caffeine | Translocation | Phenotypes | Translation | Protein biosynthesis | Rapamycin | Hygromycin | Diphtheria | Mutants | Organic chemistry | Anisomycin | Acids | Translation elongation | Viability | Saccharomyces cerevisiae | Fitness | Apoptosis | Index Medicus
Journal Article
Journal of Antibiotics, ISSN 0021-8820, 06/2008, Volume 61, Issue 6, pp. 372 - 378
More than 400 compounds isolated from soil microorganisms, and catalogued in the antibiotic library of the Kitasato Institute for Life Sciences, were screened... 
Screening | HAT | Trypanosomal brucei brucei | In vitro | T. b. rhodesiense | Antitrypanosomal antibiotics | antitrypanosomal antibiotics | VENTURICIDIN | screening | ANTIBIOTICS | TRYPANOSOMA-BRUCEI | RHODESIENSE | MICROBIOLOGY | IMMUNOLOGY | CHEMOTHERAPY | DESTOMYCINS | ANTIMALARIAL ACTIVITIES | STREPTOMYCES | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | in vitro | GAMBIENSE | PHARMACOLOGY & PHARMACY | INHIBITORS | Anthraquinones - metabolism | Macrolides - isolation & purification | Hygromycin B - isolation & purification | Trypanocidal Agents - chemistry | Hygromycin B - metabolism | Alkynes - isolation & purification | Hygromycin B - pharmacology | Macrolides - chemistry | Naphthoquinones - isolation & purification | Venturicidins - chemistry | Macrolides - pharmacology | Alkynes - metabolism | Alkynes - pharmacology | Chromones - metabolism | Chromones - pharmacology | Hygromycin B - analogs & derivatives | Cell Line | Trypanocidal Agents - metabolism | Echinomycin - chemistry | Soil Microbiology | Anthraquinones - isolation & purification | Venturicidins - pharmacology | Naphthoquinones - pharmacology | Trypanocidal Agents - isolation & purification | Venturicidins - isolation & purification | Alkynes - chemistry | Echinomycin - isolation & purification | Macrolides - metabolism | Trypanosoma brucei brucei - drug effects | Chromones - chemistry | Venturicidins - metabolism | Animals | Echinomycin - metabolism | Trypanocidal Agents - pharmacology | Chromones - isolation & purification | Echinomycin - pharmacology | Naphthoquinones - chemistry | Anthraquinones - pharmacology | Anthraquinones - chemistry | Hygromycin B - chemistry | Naphthoquinones - metabolism | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, pp. e0136231 - e0136231
Tuberculosis (TB) is the world's deadliest curable disease, responsible for an estimated 1.5 million deaths annually. A considerable challenge in controlling... 
STATIONARY-PHASE | MULTIDRUG-RESISTANT | BACTERIA | TRANSPORTERS | TUBERCULOSIS | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | GROWTH | GENE-EXPRESSION | VIBRIO-CHOLERAE | BIOFILM FORMATION | Isoniazid - pharmacology | Drug Tolerance - genetics | Epigenesis, Genetic | Humans | Hygromycin B - metabolism | Mycobacterium tuberculosis - drug effects | Ofloxacin - pharmacology | Hygromycin B - pharmacology | Biological Transport | Cinnamates - metabolism | Diffusion | Hygromycin B - analogs & derivatives | Macrophages - microbiology | Dimethylpolysiloxanes | Mycobacterium smegmatis - growth & development | Ofloxacin - metabolism | Mycobacterium smegmatis - genetics | Antitubercular Agents - pharmacology | Lab-On-A-Chip Devices | Bacterial Load | Cinnamates - pharmacology | Phenotype | Microdialysis | Models, Biological | Mycobacterium smegmatis - drug effects | Rifampin - pharmacology | Antitubercular Agents - metabolism | Isoniazid - metabolism | Mycobacterium tuberculosis - genetics | Mycobacterium tuberculosis - growth & development | Rifampin - metabolism | Complications and side effects | Mycobacterium | Tuberculosis | Mycobacteria | Physiological aspects | Antitubercular agents | Dosage and administration | Genetic aspects | Research | Drug therapy | Efflux | Cell culture | Confinement | Phenotypes | Lung diseases | Antimicrobial agents | Infections | Culture techniques | RNA polymerase | Macrophages | Drug resistance | Gene expression | Disease control | Human tissues | Medicine | Chemotherapy | Infectious diseases | Replicating | Antibiotics | Bioreactors | Drug tolerance | Pure culture | Index Medicus
Journal Article
Journal Article