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Molecular pharmaceutics, ISSN 1543-8384, 09/2017, Volume 14, Issue 9, pp. 2875 - 2883
estrone | SN-38 | bavachinin | UDP-glucuronosyltransferase | intestinal glucuronidation | AMC | recombinant UGT1A10 | estradiol | intestine microsomes | morphine | NCHN | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Coumarins - metabolism | Estradiol - metabolism | Camptothecin - metabolism | Humans | Microsomes, Liver - metabolism | Intestines - metabolism | Chromatography, High Pressure Liquid | Hymecromone - metabolism | Blotting, Western | Animals | Glucuronosyltransferase - metabolism | Estrone - metabolism | Flavonoids - metabolism | Kinetics | Camptothecin - analogs & derivatives | Diclofenac - metabolism | Index Medicus
Journal Article
The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 2006, Volume 319, Issue 3, pp. 1485 - 1491
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Acetaminophen - metabolism | Analgesics, Non-Narcotic - pharmacokinetics | Bile - metabolism | Hymecromone - metabolism | Hymecromone - analogs & derivatives | Glucuronides - metabolism | ATP-Binding Cassette Transporters - genetics | ATP-Binding Cassette Transporters - metabolism | Hymecromone - pharmacokinetics | Multidrug Resistance-Associated Proteins - genetics | Harmine - pharmacokinetics | Sulfates - metabolism | Harmine - analogs & derivatives | Liver - metabolism | Analgesics, Non-Narcotic - metabolism | Blotting, Western | Harmine - metabolism | Mice, Knockout | Animals | ATP Binding Cassette Transporter, Sub-Family B - metabolism | Mice | Acetaminophen - pharmacokinetics | In Vitro Techniques | ATP Binding Cassette Transporter, Sub-Family B - genetics | Multidrug Resistance-Associated Proteins - metabolism
Journal Article
Drug metabolism and disposition, ISSN 0090-9556, 06/2008, Volume 36, Issue 6, pp. 1056 - 1062
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Recombinant Proteins - metabolism | Cell Line | Humans | Microsomes, Liver - metabolism | Middle Aged | Male | Recombinant Proteins - genetics | Serum Albumin, Bovine - metabolism | Hymecromone - metabolism | Glucuronosyltransferase - genetics | Hymecromone - analogs & derivatives | Animals | Glucuronides - metabolism | Glucuronosyltransferase - metabolism | Cattle | Propofol - metabolism | Adult | Female | Aged | Serum Albumin - metabolism | Index Medicus
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 11/2019, Volume 294, Issue 47, pp. 17799 - 17817
chondrocyte | metabolomics | inflammation | hyaluronan | matrix metalloproteinase (MMP) | osteoarthritis | glycolysis | 4-methylumbelliferone (4MU) | pro-catabolic phenotype | extracellular matrix | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Inflammation - pathology | Interleukin-1beta - pharmacology | Hyaluronan Synthases - metabolism | Humans | Middle Aged | Male | Glycolysis - drug effects | Acetylglucosamine - metabolism | Chondrocytes - drug effects | Cartilage, Articular - metabolism | Cattle | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Adenylate Kinase - metabolism | Deoxyglucose - pharmacology | Cytoprotection - drug effects | Female | Hymecromone - pharmacology | Phosphorylation - drug effects | Chondrocytes - metabolism | Acylation | Chondrocytes - pathology | Cell Hypoxia - drug effects | Matrix Metalloproteinase 13 - metabolism | Phenotype | Animals | Signal Transduction - drug effects | Dichloroacetic Acid - pharmacology | Cartilage, Articular - drug effects | Energy Metabolism - drug effects | Index Medicus | Glycobiology and Extracellular Matrices
Journal Article
Molecular pharmacology, ISSN 0026-895X, 12/2020, Volume 98, Issue 6, pp. 710 - 718
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Medicago truncatula | Uridine Diphosphate Glucuronic Acid - metabolism | Zidovudine - metabolism | Mutagenesis, Site-Directed | Humans | Morphine - metabolism | Crystallography, X-Ray | Binding Sites - genetics | Substrate Specificity - genetics | Hymecromone - metabolism | Molecular Dynamics Simulation | Sequence Homology, Amino Acid | Coenzymes - metabolism | Glucuronosyltransferase - genetics | Plant Proteins - genetics | Glucuronides - metabolism | Glucuronosyltransferase - metabolism | Glycosides - metabolism | Arginine - genetics | HEK293 Cells | Mutation | Plant Proteins - ultrastructure | Glucosyltransferases - genetics | Glucosyltransferases - ultrastructure | Index Medicus
Journal Article
The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 04/2007, Volume 321, Issue 1, pp. 137 - 147
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Recombinant Proteins - metabolism | Microsomes - metabolism | Serum Albumin, Bovine - pharmacology | Zidovudine - metabolism | Data Interpretation, Statistical | Humans | Chromatography, High Pressure Liquid | Hymecromone - metabolism | Blotting, Western | Hymecromone - analogs & derivatives | Albumins - pharmacology | Animals | Glucuronides - metabolism | Glucuronosyltransferase - metabolism | Serum Albumin - pharmacology | Cattle | Protein Binding | Anti-HIV Agents - metabolism | Kinetics | In Vitro Techniques | Fatty Acids - metabolism
Journal Article
Experimental cell research, ISSN 0014-4827, 2009, Volume 315, Issue 11, pp. 1914 - 1923
Hyaluronan synthesis | 4-Methylumbelliferone | Hyaluronan synthase | UDP-glucuronic acid | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasms - metabolism | Uridine Diphosphate Glucuronic Acid - metabolism | Humans | Neoplasm Invasiveness - prevention & control | DNA Primers - genetics | RNA, Messenger - metabolism | RNA, Neoplasm - metabolism | Breast Neoplasms - metabolism | Glucuronosyltransferase - genetics | Hymecromone - analogs & derivatives | Neoplasms - genetics | Hyaluronic Acid - biosynthesis | Melanoma - genetics | Base Sequence | Female | Hyaluronan Synthases | Hymecromone - pharmacology | Melanoma - metabolism | RNA, Messenger - genetics | Down-Regulation - drug effects | Breast Neoplasms - drug therapy | Neoplasms - drug therapy | Cell Movement - drug effects | Breast Neoplasms - genetics | Glucuronosyltransferase - metabolism | Melanoma - drug therapy | Cell Line, Tumor | RNA, Neoplasm - genetics | Cell Proliferation - drug effects | Phosphates | Squamous cell carcinoma | Synthesis | Messenger RNA | Reverse transcriptase | Ionization | Melanoma | Lipids | Liquid chromatography | Hyaluronic acid | Mass spectrometry | Cellular biology | Protein synthesis | Cancer | Index Medicus | MAMMARY GLANDS | CATTLE | GLUCURONIC ACID | MASS SPECTROSCOPY | MELANOMAS | 60 APPLIED LIFE SCIENCES | HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY | ENDOPLASMIC RETICULUM | INHIBITION | POLYMERASE CHAIN REACTION | MESSENGER-RNA | PHOSPHATES | MICROSTRUCTURE | HYALURONIDASE
Journal Article
International journal of molecular medicine, ISSN 1107-3756, 07/2015, Volume 36, Issue 1, pp. 113 - 122
Epithelial-mesenchymal transition | Hyaluronan | Epidermal growth factor | Transforming growth factor-β1 | CD44 | Epithelial-Mesenchymal Transition - physiology | Humans | Transforming Growth Factor beta1 - metabolism | Lung Neoplasms - pathology | Extracellular Signal-Regulated MAP Kinases - metabolism | Epithelial-Mesenchymal Transition - genetics | Cell Movement - genetics | Receptor, Epidermal Growth Factor - metabolism | MCF-7 Cells | RNA Interference | Hyaluronan Receptors - metabolism | Female | Hyaluronan Synthases | Hymecromone - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Transforming Growth Factor beta1 - pharmacology | Receptor, Epidermal Growth Factor - biosynthesis | Epidermal Growth Factor - metabolism | Signal Transduction - genetics | Hyaluronan Receptors - biosynthesis | Enzyme Activation - drug effects | Hyaluronan Receptors - genetics | Glucuronosyltransferase - metabolism | Breast Neoplasms - pathology | Hyaluronic Acid - metabolism | Cell Line, Tumor | Glucuronosyltransferase - antagonists & inhibitors | RNA, Small Interfering | Neoplasm Invasiveness - genetics
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 07/2010, Volume 285, Issue 30, pp. 23276 - 23284
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Molecular Sequence Data | Esophageal Neoplasms - pathology | Gene Knockdown Techniques | Pseudopodia - drug effects | Glucuronosyltransferase - genetics | Hymecromone - analogs & derivatives | Hyaluronic Acid - biosynthesis | Base Sequence | Esophageal Neoplasms - metabolism | Hyaluronan Receptors - metabolism | Hyaluronan Synthases | Hymecromone - pharmacology | Extracellular Matrix Proteins - metabolism | Amino Acid Sequence | Glucuronosyltransferase - deficiency | Focal Adhesion Protein-Tyrosine Kinases - metabolism | Cell Movement - drug effects | Focal Adhesions - drug effects | Phenotype | Animals | Pseudopodia - metabolism | Focal Adhesions - metabolism | Hyaluronic Acid - metabolism | Cell Line, Tumor | Cell Proliferation - drug effects | Index Medicus | Cancer Therapy | Cell Surface | Extracellular Matrix | Hyaluronan Synthase | Cytoskeleton | Esophageal Cancer | Glycobiology and Extracellular Matrices | Hyaluronate | Cell Adhesion
Journal Article
Cancer research (Chicago, Ill.), ISSN 0008-5472, 04/2010, Volume 70, Issue 7, pp. 2613 - 2623
Life Sciences & Biomedicine | Oncology | Science & Technology | Tumors of the urinary system | Urinary tract. Prostate gland | Gynecology. Andrology. Obstetrics | Pharmacology. Drug treatments | Nephrology. Urinary tract diseases | Biological and medical sciences | Medical sciences | Antineoplastic agents | Male genital diseases | Tumors | Prostatic Neoplasms - metabolism | Apoptosis - drug effects | Humans | Male | Neovascularization, Pathologic - pathology | Hymecromone - analogs & derivatives | Hymecromone - pharmacology | Interleukin-8 - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Prostatic Neoplasms - drug therapy | Prostatic Neoplasms - blood supply | Prostatic Neoplasms - pathology | Receptors, Interleukin-8 - metabolism | Cell Growth Processes - drug effects | Neoplasm Invasiveness | Hyaluronic Acid - antagonists & inhibitors | Chemotaxis - drug effects | Down-Regulation - drug effects | Receptors, CXCR4 - metabolism | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Neovascularization, Pathologic - drug therapy | Hyaluronic Acid - metabolism | Cell Line, Tumor | Mice | Neovascularization, Pathologic - metabolism | Index Medicus | 4-methylumbelliferone | prostate cancer | Hyaluronic acid | Hyaluronic acid receptors
Journal Article
Comparative biochemistry and physiology. Toxicology & pharmacology, ISSN 1532-0456, 01/2014, Volume 159, Issue 1, pp. 31 - 37
Reactive oxygen species | Bombyx mori | Fat body | 4-Methylumbelliferone | Anti-oxidant | Oxidative stress response | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Toxicology | Life Sciences & Biomedicine | Zoology | Science & Technology | Glutathione Peroxidase - metabolism | Reactive Oxygen Species - metabolism | Glutathione - metabolism | Glutathione Reductase - metabolism | Antioxidants - metabolism | Larva - metabolism | Bombyx - drug effects | Hydrogen Peroxide - metabolism | Catalase - metabolism | Bombyx - metabolism | Animals | Larva - drug effects | Fat Body - drug effects | Hymecromone - pharmacology | NADP - metabolism | Oxidative Stress - drug effects | Fat Body - metabolism | Coumarins | Analysis | Index Medicus
Journal Article
Comparative biochemistry and physiology. Toxicology & pharmacology, ISSN 1532-0456, 2009, Volume 149, Issue 3, pp. 334 - 339
Animal model | Pharmacodynamics | Metabolism | Toxicity | Insect | Silkworm | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Toxicology | Life Sciences & Biomedicine | Zoology | Science & Technology | Drug Evaluation, Preclinical - methods | Larva - metabolism | Coumarins - pharmacokinetics | Cytochrome P-450 Enzyme System - metabolism | Hemolymph - metabolism | Glucuronates - metabolism | Bombyx - drug effects | Lethal Dose 50 | Umbelliferones - pharmacokinetics | Feasibility Studies | Hymecromone - analogs & derivatives | Bombyx - metabolism | Animals | Feces - chemistry | Larva - drug effects | Biotransformation | Bombyx - enzymology | Hymecromone - pharmacokinetics | Models, Animal | Toxicity Tests - methods | Insect Proteins - metabolism | Drugs | Analysis | Physiological aspects | Coumarins | Models | Glucose | Sulfates | Dextrose | Index Medicus
Journal Article