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Journal Article
Journal of Neuroscience, ISSN 0270-6474, 09/2003, Volume 23, Issue 23, pp. 8370 - 8379
Nerve injury-induced afferent discharge is thought to elicit spinal sensitization and consequent abnormal pain. Experimental neuropathic pain, however, also... 
RVM | CGRP release | Primary afferent | Descending facilitation | Dynorphin | Neuropathic pain | RAT SPINAL-CORD | dynorphin | GENE-RELATED PEPTIDE | PRIMARY AFFERENT NEURONS | SUBSTANCE-P RELEASE | PAINFUL PERIPHERAL NEUROPATHY | DORSAL-ROOT GANGLION | NEUROSCIENCES | primary afferent | neuropathic pain | INDUCED TACTILE ALLODYNIA | NERVE-INJURED RATS | VASOACTIVE INTESTINAL POLYPEPTIDE | descending facilitation | ROSTRAL VENTROMEDIAL MEDULLA | Spinal Cord - drug effects | Spinal Cord - metabolism | Recombinant Fusion Proteins - pharmacology | Capsaicin - pharmacology | Enkephalins - metabolism | Afferent Pathways - physiopathology | Analgesics, Opioid - pharmacology | Male | Nerve Compression Syndromes - complications | Medulla Oblongata - physiopathology | Ligation | Lumbosacral Region | Neuralgia - etiology | N-Glycosyl Hydrolases | Neuralgia - physiopathology | Calcitonin Gene-Related Peptide - metabolism | Dynorphins - metabolism | Disease Models, Animal | Afferent Pathways - metabolism | Spinal Nerves - physiopathology | Microinjections | Medulla Oblongata - drug effects | Receptors, Opioid, mu - drug effects | Receptors, Opioid, mu - metabolism | Ribosome Inactivating Proteins, Type 1 | Neurotransmitter Agents - metabolism | Rats | Pain Measurement - drug effects | Spinal Nerves - metabolism | Rats, Sprague-Dawley | Protein Precursors - metabolism | Hyperesthesia - physiopathology | Hyperesthesia - etiology | Animals | Opioid Peptides | Neuronal Plasticity | Spinal Cord - physiopathology | Oligopeptides - pharmacology | Nerve Compression Syndromes - physiopathology | Sensory Thresholds - drug effects | Behavioral | Cognitive | Systems
Journal Article
Neurogastroenterology & Motility, ISSN 1350-1925, 04/2012, Volume 24, Issue 4, pp. 376 - e172
Journal Article
Journal Article
Journal Article
Neuroscience Letters, ISSN 0304-3940, 2006, Volume 396, Issue 1, pp. 44 - 49
Opiates are commonly used to treat moderate to severe pain and can be used over prolonged periods in states of chronic pain such as those associated with... 
Opioid | Tactile hyperesthesia | Antinociceptive tolerance | Dynorphin | Hyperalgesia | LONG-LASTING ALLODYNIA | dynorphin | opioid | INCREASES | tactile hyperesthesia | MORPHINE-METABOLISM | NEUROSCIENCES | SPINAL DYNORPHIN | EXCITATORY AMINO-ACIDS | NEUROPATHIC PAIN | ABNORMAL PAIN | NERVE-INJURED RATS | DESCENDING FACILITATION | antinociceptive tolerance | HUMAN-BRAIN | hyperalgesia | Hyperalgesia - chemically induced | Pain Threshold - physiology | Receptors, Opioid - agonists | Central Nervous System - metabolism | Afferent Pathways - physiopathology | Drug Tolerance - physiology | Neuronal Plasticity - drug effects | Spinal Nerve Roots - metabolism | Male | Pain - chemically induced | Pain - metabolism | Isomerism | Narcotics - adverse effects | Neuronal Plasticity - physiology | Nociceptors - physiopathology | Spinal Nerve Roots - physiopathology | Oxymorphone - adverse effects | Up-Regulation - physiology | Pain Threshold - drug effects | Afferent Pathways - drug effects | Dynorphins - metabolism | Disease Models, Animal | Receptors, Opioid - metabolism | Afferent Pathways - metabolism | Drug Administration Schedule | Hyperalgesia - metabolism | Receptors, Opioid, mu - drug effects | Receptors, Opioid, mu - metabolism | Rats | Pain Measurement - drug effects | Rats, Sprague-Dawley | Hyperalgesia - physiopathology | Up-Regulation - drug effects | Animals | Dynorphins - drug effects | Pain - physiopathology | Central Nervous System - drug effects | Nociceptors - metabolism | Central Nervous System - physiopathology | Nociceptors - drug effects | Spinal Nerve Roots - drug effects | Care and treatment | Pain | Analgesics | Oncology, Experimental | Research | Enantiomers | Cancer
Journal Article