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The Lancet. Haematology, ISSN 2352-3026, 05/2016, Volume 3, Issue 5, pp. e217 - e227
Summary Background Standard treatment for patients with primary CNS lymphoma remains to be defined. Active therapies are often associated with increased risk... 
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Hematology | Science & Technology | Follow-Up Studies | Cytarabine - therapeutic use | Humans | Lymphoma, B-Cell - therapy | Middle Aged | Male | Comparative Effectiveness Research | Hyperglycemia - chemically induced | Radiotherapy, Adjuvant - adverse effects | Hematopoietic Stem Cell Transplantation - adverse effects | Lymphoma, B-Cell - diagnostic imaging | Transplantation Conditioning - methods | Rituximab - adverse effects | Induction Chemotherapy - methods | Anemia - chemically induced | Central Nervous System Neoplasms - therapy | Thrombocytopenia - chemically induced | Mucositis - chemically induced | Magnetic Resonance Imaging | Methotrexate - adverse effects | Dexamethasone - therapeutic use | Radiotherapy, Adjuvant - methods | Transplantation, Autologous - adverse effects | Heart Injuries - chemically induced | Italy | Hematopoietic Stem Cell Transplantation - methods | Central Nervous System Neoplasms - mortality | Germany | Thiotepa - adverse effects | Thiotepa - therapeutic use | Thrombosis - chemically induced | Infections - chemically induced | Intraocular Lymphoma - therapy | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Cytarabine - adverse effects | Methotrexate - therapeutic use | Rituximab - therapeutic use | Stroke - chemically induced | Optic Nerve Neoplasms - diagnostic imaging | Poisoning - epidemiology | Female | Remission Induction - methods | Transplantation Conditioning - adverse effects | Acute Kidney Injury - chemically induced | Neutropenia - chemically induced | Optic Nerve Neoplasms - therapy | Death, Sudden - epidemiology | Lymphoma, B-Cell - mortality | Intraocular Lymphoma - diagnostic imaging | Kaplan-Meier Estimate | Chemical and Drug Induced Liver Injury - epidemiology | Treatment Outcome | United Kingdom | Combined Modality Therapy - adverse effects | Switzerland | Induction Chemotherapy - adverse effects | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Central Nervous System Neoplasms - diagnostic imaging | Denmark | Combined Modality Therapy - methods | Neurotoxicity Syndromes - epidemiology | Gastrointestinal Diseases - chemically induced | Index Medicus
Journal Article
The lancet oncology, ISSN 1470-2045, 06/2017, Volume 18, Issue 6, pp. 770 - 778
Summary Background Pancreatic cancer statistics are dismal, with a 5-year survival of less than 10%, and more than 50% of patients presenting with metastatic... 
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Leucovorin - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Sulfides - administration & dosage | Pancreatic Neoplasms - drug therapy | Organoplatinum Compounds - administration & dosage | Fluorouracil - administration & dosage | Hyperglycemia - chemically induced | Leucovorin - adverse effects | Fluorouracil - adverse effects | Hypokalemia - chemically induced | Camptothecin - administration & dosage | Female | Neutropenia - chemically induced | Camptothecin - analogs & derivatives | Camptothecin - adverse effects | Hematologic Diseases - chemically induced | Sensation Disorders - chemically induced | Abdominal Pain - chemically induced | Pancreatic Neoplasms - pathology | Anemia - chemically induced | Thrombocytopenia - chemically induced | Adenocarcinoma - drug therapy | Adenocarcinoma - secondary | Hypoalbuminemia - chemically induced | Maximum Tolerated Dose | Sepsis - chemically induced | Sulfides - adverse effects | Aged | Caprylates - administration & dosage | Caprylates - adverse effects | Organoplatinum Compounds - adverse effects | Lymphopenia - chemically induced | Enzymes | Medical colleges | Care and treatment | Metastasis | Antineoplastic agents | Cells | Antimitotic agents | Cancer patients | Chemotherapy | Pancreatic cancer | Physiological aspects | Product development | Cancer | Index Medicus
Journal Article
Toxicology and applied pharmacology, ISSN 0041-008X, 12/2014, Volume 281, Issue 2, pp. 211 - 220
...), to continuously deliver non-concentrated PM for subchronic exposure. A type 1 DM rat model was induced using streptozotocin... 
Rats | Air pollution | Inflammation | Particulate matter | Diabetes mellitus | Pharmacology & Pharmacy | Toxicology | Life Sciences & Biomedicine | Science & Technology | Inflammation - chemically induced | Particulate Matter - toxicity | Myocarditis - chemically induced | Streptozocin | Glycated Hemoglobin A - metabolism | Homeostasis | Male | Diabetes Complications - diagnosis | Diabetic Nephropathies - blood | Inflammation - blood | Diabetes Mellitus, Experimental - blood | Time Factors | Interleukin-6 - blood | Diabetes Mellitus, Type 1 - chemically induced | Inhalation Exposure - adverse effects | Diabetes Mellitus, Experimental - chemically induced | Diabetic Cardiomyopathies - blood | Inflammation - diagnosis | Diabetic Angiopathies - chemically induced | Diabetes Mellitus, Experimental - diagnosis | Risk Factors | Diabetic Nephropathies - chemically induced | Inflammation Mediators - blood | Toxicity Tests, Subchronic | Biomarkers - blood | Diabetic Angiopathies - blood | Myocarditis - blood | Diabetes Complications - blood | Rats, Sprague-Dawley | Blood Glucose - drug effects | Particle Size | Diabetes Complications - chemically induced | Animals | Diabetes Mellitus, Type 1 - blood | Fibrinogen - metabolism | Blood Glucose - metabolism | Diabetic Cardiomyopathies - chemically induced | Glucose metabolism | Type 1 diabetes | Fibrinogen | Hemoglobin | Glucose | Health aspects | Dextrose | Index Medicus | HOMEOSTASIS | INJURIES | RATS | AIR | COMPARATIVE EVALUATIONS | 60 APPLIED LIFE SCIENCES | AIR POLLUTION | DAMAGE | KIDNEYS | STREPTOZOCIN | GLOBAL ASPECTS | HYPERGLYCEMIA | BLOOD VESSELS | GLUCOSE | INFLAMMATION | DIABETES MELLITUS | FIBRINOGEN
Journal Article
European journal of cancer (1990), ISSN 0959-8049, 05/2017, Volume 76, pp. 36 - 44
Abstract Background The phosphatidylinositol-3-kinase (PI3K)/protein kinase B (Akt) signalling axis and androgen receptor (AR) pathways exhibit reciprocal... 
Hematology, Oncology and Palliative Medicine | Dactolisib (BEZ235) | Castration-resistant prostate cancer (CRPC) | Buparlisib (BKM120) | Abiraterone acetate (AA) | Life Sciences & Biomedicine | Oncology | Science & Technology | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Area Under Curve | Humans | Middle Aged | Aminopyridines - pharmacokinetics | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Imidazoles - administration & dosage | Male | Imidazoles - pharmacokinetics | Diarrhea - chemically induced | Quinolines - administration & dosage | Fever - chemically induced | Quinolines - pharmacokinetics | Chills - chemically induced | Abiraterone Acetate - administration & dosage | Hyperglycemia - chemically induced | Aged, 80 and over | Kallikreins - blood | Abiraterone Acetate - pharmacokinetics | Aminopyridines - administration & dosage | Prostatic Neoplasms, Castration-Resistant - blood | Morpholines - administration & dosage | Prostatic Neoplasms, Castration-Resistant - drug therapy | Prostate-Specific Antigen - blood | Asthenia - chemically induced | Vomiting - chemically induced | Maximum Tolerated Dose | Stomatitis - chemically induced | Aged | Morpholines - pharmacokinetics | TOR protein | Toxicity | Prostate-specific antigen | Homology | AKT protein | Metastases | Anticancer properties | Proteins | Chills | Signal transduction | Hyperglycemia | Occupational safety | Castration | Vomiting | Safety | Tensin | Medical treatment | Diarrhea | Pharmacology | Rapamycin | Prednisone | Patients | Fever | 1-Phosphatidylinositol 3-kinase | Androgens | Stomatitis | Inhibitors | Asthenia | Pharmacokinetics | Acetic acid | Human behavior | Prostate cancer | Prostate | PTEN protein | Cancer | Index Medicus
Journal Article