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Cell Metabolism, ISSN 1550-4131, 05/2012, Volume 15, Issue 5, pp. 725 - 738
Mammalian target of rapamycin complex 2 (mTORC2) phosphorylates and activates AGC kinase family members, including Akt, SGK1, and PKC, in response to... 
TRANSCRIPTION FACTORS | LIPID-METABOLISM | INSULIN-RESISTANCE | ELEMENT-BINDING PROTEIN-1C | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | MOTIF PHOSPHORYLATION | DIABETIC-NEPHROPATHY | GLUCOSE-UTILIZATION | CELL-GROWTH | PHOSPHOINOSITIDE 3-KINASE | CELL BIOLOGY | Glucose Intolerance - metabolism | Phosphorylation | Liver - enzymology | TOR Serine-Threonine Kinases - metabolism | Homeostasis | Glycogen Synthase Kinase 3 beta | Male | Hepatocytes - metabolism | Mechanistic Target of Rapamycin Complex 2 | Hyperglycemia - genetics | Proto-Oncogene Proteins c-akt - genetics | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - metabolism | Forkhead Transcription Factors - metabolism | Trans-Activators - genetics | Hyperinsulinism - genetics | Insulin - genetics | Lipogenesis | Proto-Oncogene Proteins c-akt - metabolism | Sterol Regulatory Element Binding Protein 1 - metabolism | Gluconeogenesis | Hyperinsulinism - metabolism | Glucose Intolerance - genetics | Signal Transduction | Liver - metabolism | Glucokinase - genetics | Glucose - genetics | Lipid Metabolism | Forkhead Transcription Factors - genetics | Glucokinase - metabolism | Glycogen Synthase Kinase 3 - metabolism | Mice, Knockout | Hyperglycemia - metabolism | Proteins - genetics | Insulin - metabolism | Animals | Proteins - metabolism | Trans-Activators - deficiency | Glycogen Synthase Kinase 3 - genetics | Sterol Regulatory Element Binding Protein 1 - genetics | Glucose - metabolism | Glycolysis | Trans-Activators - metabolism | Forkhead Box Protein O1 | Mice | Transcription Factors | Glucose metabolism | Hyperglycemia | Glucose | Isoenzymes | Dextrose | Index Medicus
Journal Article
Journal of Immunology, ISSN 0022-1767, 01/2014, Volume 192, Issue 2, pp. 623 - 629
Chronic inflammation is known to promote metabolic dysregulation in obesity and type 2 diabetes. Although the precise origin of the unchecked inflammatory... 
IMMUNE-SYSTEM | INFLAMMATION | DISEASE | RESISTANCE | FAT | AKT | IMMUNOLOGY | DIET-INDUCED OBESITY | KEY PLAYERS | ADIPOSE-TISSUE | CUTTING EDGE | Tumor Necrosis Factor-alpha - metabolism | Antigens, CD - immunology | T-Lymphocytes, Regulatory - metabolism | Epithelial Cells - metabolism | TOR Serine-Threonine Kinases - metabolism | Obesity - immunology | Insulin - immunology | Interferon-gamma - metabolism | Antigens, CD - metabolism | T-Lymphocytes, Regulatory - immunology | Epithelium - immunology | Signal Transduction - immunology | Inflammation - metabolism | Tumor Necrosis Factor-alpha - immunology | Interleukin-10 - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Receptor, Insulin - immunology | Macrophages - immunology | Hyperinsulinism - metabolism | Intra-Abdominal Fat - immunology | Transforming Growth Factor beta - immunology | Epithelium - metabolism | Mice, Inbred C57BL | Apyrase - metabolism | Cells, Cultured | Apyrase - immunology | CTLA-4 Antigen - metabolism | Inflammation - immunology | CTLA-4 Antigen - immunology | Intra-Abdominal Fat - metabolism | Obesity - metabolism | TOR Serine-Threonine Kinases - immunology | Insulin - metabolism | Macrophages - metabolism | Animals | Hyperinsulinism - immunology | Proto-Oncogene Proteins c-akt - immunology | Epithelial Cells - immunology | Interferon-gamma - immunology | Interleukin-10 - antagonists & inhibitors | Receptor, Insulin - metabolism | Mice | Interleukin-10 - immunology | Transforming Growth Factor beta - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
Cell Metabolism, ISSN 1550-4131, 12/2012, Volume 16, Issue 6, pp. 723 - 737
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 03/2017, Volume 102, Issue 3, pp. 810 - 821
Context: Polycystic ovary syndrome ( PCOS) is a complex syndrome showing clinical features of an endocrine/metabolic disorder, including hyperinsulinemia and... 
POLYCYSTIC-OVARY-SYNDROME | IONIZATION-MASS-SPECTROMETRY | RISK-FACTORS | TESTOSTERONE | BIOLOGICAL SAMPLES | ENDOCRINOLOGY & METABOLISM | IMPAIRED GLUCOSE-TOLERANCE | NONALCOHOLIC STEATOHEPATITIS | FAT-CELL LIPOLYSIS | OLDER CHINESE | OBESE WOMEN | Arachidonic Acid - metabolism | Gas Chromatography-Mass Spectrometry | Linoleic Acid - metabolism | Humans | Dehydroepiandrosterone Sulfate - metabolism | Case-Control Studies | Young Adult | Testosterone - metabolism | Polycystic Ovary Syndrome - complications | Diet, High-Fat | Mass Spectrometry | Chromatography, Liquid | Adult | Female | Hyperandrogenism - metabolism | Fatty Acids - metabolism | Phosphatidylglycerols - metabolism | Disease Models, Animal | Hyperinsulinism - metabolism | Ceramides - metabolism | Hyperinsulinism - complications | Polycystic Ovary Syndrome - metabolism | Cholesterol, HDL - metabolism | Obesity - complications | Eicosapentaenoic Acid - metabolism | Rats | Sex Hormone-Binding Globulin - metabolism | Lipid Metabolism | Fatty Acids, Unsaturated - metabolism | Rats, Sprague-Dawley | Obesity - metabolism | Triglycerides - metabolism | Hyperandrogenism - complications | Insulin - metabolism | Animals | Cholesterol, LDL - metabolism | Phosphatidic Acids - metabolism | Androgens - metabolism | Blood Glucose - metabolism | Docosahexaenoic Acids - metabolism | Polycystic ovary syndrome | Obesity | Hyperinsulinemia | Lecithin | Polyunsaturated fatty acids | Lipids | Mass spectroscopy | Liquid chromatography | Phospholipids | Metabolism | Arachidonic acid | Insulin | Fatty acids | Patients | Chromatography | Biological activity | Subgroups | Gas chromatography | Androgens | Molecular modelling | Metabolites | Lipid metabolism | Mass spectrometry | Metabolic disorders | Index Medicus | Abridged Index Medicus
Journal Article
Cell Metabolism, ISSN 1550-4131, 2007, Volume 5, Issue 6, pp. 438 - 449
Journal Article
Cell Metabolism, ISSN 1550-4131, 04/2005, Volume 1, Issue 4, pp. 245 - 258
Obesity is typically associated with elevated levels of free fatty acids (FFAs) and is linked to glucose intolerance and type 2 diabetes. FFAs exert divergent... 
STIMULATED INSULIN-SECRETION | PROTEIN-COUPLED RECEPTOR | FREE FATTY-ACIDS | ENDOCRINOLOGY & METABOLISM | LONG-TERM EXPOSURE | GENE-EXPRESSION | PANCREATIC BETA-CELLS | PPAR-GAMMA | UNCOUPLING PROTEIN-2 | DIET-INDUCED OBESITY | ADIPOSE-TISSUE | CELL BIOLOGY | Glucose Intolerance - metabolism | Hyperinsulinism - metabolism | Glucose Intolerance - genetics | Fatty Liver - metabolism | Hypertriglyceridemia - genetics | Receptors, G-Protein-Coupled - metabolism | Diabetes Mellitus, Type 2 - genetics | Hypertriglyceridemia - metabolism | Diabetes Mellitus, Type 2 - metabolism | Insulin - metabolism | Animals | Diabetes Mellitus, Type 2 - physiopathology | Receptors, G-Protein-Coupled - deficiency | Glucose - physiology | Islets of Langerhans - metabolism | Homeostasis - physiology | Mice | Receptors, G-Protein-Coupled - genetics | Insulin Secretion | Type 2 diabetes | Obesity | Hyperglycemia | Homeostasis | Glucose | Fatty acids | Insulin | Dextrose | Membrane proteins | Index Medicus | Fatty Liver/metabolism | Glucose Intolerance/genetics/metabolism | Hypertriglyceridemia/genetics/metabolism | Receptors; G-Protein-Coupled/deficiency/genetics/metabolism | Homeostasis/physiology | Insulin/secretion | Hyperinsulinism/metabolism | Diabetes Mellitus; Type 2/genetics/metabolism/physiopathology | Islets of Langerhans/metabolism | Glucose/physiology
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 510, Issue 7506, pp. 547 - 551
Journal Article
Nature, ISSN 0028-0836, 12/2004, Volume 432, Issue 7020, pp. 1027 - 1032
Journal Article
Diabetes, ISSN 0012-1797, 10/2010, Volume 59, Issue 10, pp. 2444 - 2452
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 2005, Volume 115, Issue 12, pp. 3554 - 3563
Journal Article
Journal Article