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Lancet, The, ISSN 0140-6736, 2010, Volume 375, Issue 9719, pp. 998 - 1006
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2012, Volume 366, Issue 12, pp. 1108 - 1118
A monoclonal antibody to PCSK9 was studied in two single-dose trials in healthy volunteers and one multiple-dose trial in patients with familial or nonfamilial... 
POPULATION | MEDICINE, GENERAL & INTERNAL | STATIN | MICE | MUTATIONS | Proprotein Convertases - antagonists & inhibitors | Injections, Intravenous | Heptanoic Acids - therapeutic use | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Male | Hypercholesterolemia - drug therapy | Dose-Response Relationship, Drug | Injections, Subcutaneous | Serine Endopeptidases - immunology | Adult | Cholesterol, LDL - blood | Female | Hyperlipoproteinemia Type II - drug therapy | Drug Therapy, Combination | Pyrroles - therapeutic use | Proprotein Convertases - metabolism | Receptors, LDL - metabolism | Lipoproteins - blood | Anticholesteremic Agents - adverse effects | Proprotein Convertases - immunology | Hyperlipoproteinemia Type II - metabolism | Atorvastatin Calcium | Anticholesteremic Agents - therapeutic use | Antibodies, Monoclonal - administration & dosage | Anticholesteremic Agents - administration & dosage | Least-Squares Analysis | Serine Endopeptidases - metabolism | Receptors, LDL - drug effects | Hypercholesterolemia - metabolism | Proprotein Convertase 9 | Drugs | Dose-response relationship (Biochemistry) | Hypercholesterolemia | Monoclonal antibodies | Cholesterol, LDL | Dosage and administration | Product/Service Evaluations | Research | Drug therapy | Health aspects | Studies | Lipoproteins (low density) | Kexin | Serine | Atorvastatin | Cardiovascular disease | Subtilisin | Low density lipoprotein | Cholesterol | Index Medicus | Abridged Index Medicus
Journal Article
Circulation, ISSN 0009-7322, 11/2012, Volume 126, Issue 19, pp. 2283 - 2292
Journal Article
Circulation, ISSN 0009-7322, 05/2015, Volume 131, Issue 21, pp. 1861 - 1871
BACKGROUND—Fibroblast growth factor 21 (FGF21) is a metabolic hormone with pleiotropic effects on glucose and lipid metabolism and insulin sensitivity. It acts... 
Fibroblast growth factor 21 | Hormones | Adipokines | Atherosclerosis | atherosclerosis | fibroblast growth factor 21 | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | LIPID-METABOLISM | hormones | PGC-1-ALPHA | INSULIN SENSITIVITY | PROTECTS | ENERGY-EXPENDITURE | LIVER | PERIPHERAL VASCULAR DISEASE | adipokines | EXPRESSION | TRANSGENIC MICE | FGF21 | Recombinant Proteins - therapeutic use | Adiponectin - biosynthesis | Apolipoproteins E - deficiency | Atherosclerosis - genetics | Adipocytes - drug effects | Adiponectin - physiology | Sterol Regulatory Element Binding Protein 2 - biosynthesis | Membrane Proteins - deficiency | RNA, Messenger - biosynthesis | Liver - drug effects | Membrane Proteins - physiology | Adiponectin - genetics | Adiponectin - deficiency | Sterol Regulatory Element Binding Protein 2 - genetics | Fibroblast Growth Factors - therapeutic use | Hyperlipoproteinemia Type II - complications | Atherosclerosis - drug therapy | Liver - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Fibroblast Growth Factors - deficiency | Atherosclerosis - metabolism | Sterol Regulatory Element Binding Protein 2 - physiology | Mice, Knockout | Gene Expression Regulation - drug effects | Hyperlipoproteinemia Type II - metabolism | Receptor, Fibroblast Growth Factor, Type 2 - physiology | Animals | Signal Transduction - drug effects | Endothelium, Vascular - metabolism | Receptor, Fibroblast Growth Factor, Type 2 - drug effects | Adipocytes - metabolism | Membrane Proteins - drug effects | Endothelium, Vascular - pathology | Mice | Cholesterol - biosynthesis | Atherosclerosis - prevention & control | Hyperlipoproteinemia Type II - genetics | Index Medicus | Abridged Index Medicus | 134 | 147 | 90 | Original
Journal Article
Atherosclerosis, ISSN 0021-9150, 2013, Volume 229, Issue 1, pp. 79 - 85
Journal Article
Journal Article
Atherosclerosis, ISSN 0021-9150, 2012, Volume 223, Issue 2, pp. 394 - 400
Journal Article