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Circulation, ISSN 0009-7322, 04/2007, Volume 115, Issue 14, pp. 1948 - 1967
Despite compliance with lifestyle recommendations, some children and adolescents with high-risk hyperlipidemia will require lipid-lowering drug therapy,... 
Drugs | Pediatrics | Lipids | Hypercholesterolemia | AHA Scientific Statements | FACTOR INTERVENTION PROJECT | INTIMA-MEDIA THICKNESS | DEPENDENT DIABETES-MELLITUS | lipids | CARDIAC & CARDIOVASCULAR SYSTEMS | LOW-CHOLESTEROL DIET | drugs | LOW-DENSITY-LIPOPROTEIN | RESTORES ENDOTHELIAL FUNCTION | BODY-FAT DISTRIBUTION | hypercholesterolemia | BLOOD-PRESSURE | pediatrics | HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA | PERIPHERAL VASCULAR DISEASE | LOW-SATURATED-FAT | Dyslipidemias - complications | Humans | Hyperlipoproteinemias - epidemiology | Middle Aged | Child, Preschool | Male | Arteriosclerosis - epidemiology | Phytotherapy | Child | Dyslipidemias - diagnosis | Metabolic Syndrome - epidemiology | Arteriosclerosis - etiology | HIV Protease Inhibitors - adverse effects | Hypolipidemic Agents - adverse effects | Arteriosclerosis - diagnostic imaging | Risk Factors | Combined Modality Therapy | Disease Progression | Arteriosclerosis - prevention & control | Diet, Fat-Restricted | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Hyperlipoproteinemia Type II - diet therapy | Adolescent | Age of Onset | HIV Infections - complications | Hypolipidemic Agents - therapeutic use | Arteriosclerosis - pathology | Cholesterol, Dietary | Dyslipidemias - diet therapy | Hyperlipoproteinemias - classification | Age Factors | Hyperlipoproteinemia Type II - diagnosis | Infant | Exercise Therapy | Contraindications | Dietary Fats | Hyperlipoproteinemias - drug therapy | Ultrasonography | Diabetes Complications - epidemiology | Adult | Cholesterol, LDL - blood | Female | Anticholesteremic Agents - classification | Hyperlipoproteinemia Type II - drug therapy | Hyperlipoproteinemia Type II - complications | Dyslipidemias - drug therapy | Clinical Trials as Topic | Anticholesteremic Agents - therapeutic use | Hyperlipoproteinemia Type II - epidemiology | Obesity - epidemiology | Hypolipidemic Agents - administration & dosage | HIV Infections - drug therapy | Hyperlipoproteinemias - genetics | Care and treatment | Demographic aspects | Hyperlipidemia | Research | Drug therapy | Risk factors
Journal Article
Circulation, ISSN 0009-7322, 11/2012, Volume 126, Issue 19, pp. 2283 - 2292
Journal Article
Journal Article
JAMA, ISSN 0098-7484, 08/2016, Volume 316, Issue 7, pp. 743 - 753
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2012, Volume 366, Issue 12, pp. 1108 - 1118
A monoclonal antibody to PCSK9 was studied in two single-dose trials in healthy volunteers and one multiple-dose trial in patients with familial or nonfamilial... 
POPULATION | MEDICINE, GENERAL & INTERNAL | STATIN | MICE | MUTATIONS | Proprotein Convertases - antagonists & inhibitors | Injections, Intravenous | Heptanoic Acids - therapeutic use | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Male | Hypercholesterolemia - drug therapy | Dose-Response Relationship, Drug | Injections, Subcutaneous | Serine Endopeptidases - immunology | Adult | Cholesterol, LDL - blood | Female | Hyperlipoproteinemia Type II - drug therapy | Drug Therapy, Combination | Pyrroles - therapeutic use | Proprotein Convertases - metabolism | Receptors, LDL - metabolism | Lipoproteins - blood | Anticholesteremic Agents - adverse effects | Proprotein Convertases - immunology | Hyperlipoproteinemia Type II - metabolism | Atorvastatin Calcium | Anticholesteremic Agents - therapeutic use | Antibodies, Monoclonal - administration & dosage | Anticholesteremic Agents - administration & dosage | Least-Squares Analysis | Serine Endopeptidases - metabolism | Receptors, LDL - drug effects | Hypercholesterolemia - metabolism | Proprotein Convertase 9 | Drugs | Dose-response relationship (Biochemistry) | Hypercholesterolemia | Monoclonal antibodies | Cholesterol, LDL | Dosage and administration | Product/Service Evaluations | Research | Drug therapy | Health aspects | Studies | Lipoproteins (low density) | Kexin | Serine | Atorvastatin | Cardiovascular disease | Subtilisin | Low density lipoprotein | Cholesterol
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 04/2007, Volume 356, Issue 16, pp. 1620 - 1630
Since torcetrapib, an inhibitor of cholesteryl ester transfer protein, markedly increases levels of high-density lipoprotein cholesterol and lowers levels of... 
INTIMA-MEDIA THICKNESS | MEDICINE, GENERAL & INTERNAL | TRANSFER PROTEIN INHIBITOR | CHOLESTERYL ESTER TRANSFER | CARDIOVASCULAR-DISEASE | DOUBLE-BLIND | RISK | SECONDARY PREVENTION | PROGRESSION | HIGH-DENSITY-LIPOPROTEIN | ATORVASTATIN | Carotid Arteries - drug effects | Cholesterol Ester Transfer Proteins - antagonists & inhibitors | Prospective Studies | Heptanoic Acids - therapeutic use | Humans | Middle Aged | Male | Quinolines - pharmacology | Atherosclerosis - etiology | Carotid Artery Diseases - pathology | Adult | Cholesterol, LDL - blood | Female | Hyperlipoproteinemia Type II - drug therapy | Drug Therapy, Combination | Pyrroles - therapeutic use | Carotid Artery Diseases - drug therapy | Hyperlipoproteinemia Type II - complications | Atherosclerosis - pathology | Atherosclerosis - drug therapy | Carotid Artery Diseases - etiology | Double-Blind Method | Hyperlipoproteinemia Type II - blood | Disease Progression | Atorvastatin Calcium | Anticholesteremic Agents - therapeutic use | Cholesterol, HDL - blood | Heterozygote | Carotid Arteries - pathology | Quinolines - therapeutic use | Anticholesteremic Agents - pharmacology | Hypercholesterolemia | High density lipoproteins | Atherosclerosis | Anticholesteremic agents | Dosage and administration | Research | Drug therapy | Cardiovascular disease | Diet | Apolipoproteins | Cholesterol
Journal Article
Journal Article
Lancet, The, ISSN 0140-6736, 2015, Volume 385, Issue 9983, pp. 2153 - 2161
Journal Article
Journal Article
Journal Article