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Magnetic Resonance in Medicine, ISSN 0740-3194, 12/2016, Volume 76, Issue 6, pp. spcone - spcone
Purpose We characterized the performance of a novel hyperpolarized perfusion marker, alpha -trideuteromethyl[15N]glutamine, for direct comparison with a... 
kidney | perfusion | hyperpolarized 15N
Journal Article
Journal of Magnetic Resonance Imaging, ISSN 1053-1807, 10/2011, Volume 34, Issue 4, pp. 831 - 841
Purpose: To develop an automated segmentation method to differentiate the ventilated lung volume on 3He magnetic resonance imaging (MRI). Materials and... 
hyperpolarized 3He | segmentation | ventilation defects | hyperpolarized
Journal Article
Magnetic Resonance in Medicine, ISSN 0740-3194, 04/2013, Volume 69, Issue 4, pp. 1063 - 1071
Spatially resolved images of hyperpolarized 13C substrates and their downstream products provide insight into real‐time metabolic processes occurring in vivo.... 
hyperpolarized 13C | cardiac metabolism | pyruvate | hyperpolarized
Journal Article
Experimental Cell Research, ISSN 0014-4827, 05/2019, Volume 378, Issue 1, pp. 51 - 56
Diabetic kidney disease (DKD) is associated with altered metabolic patterns, leading to increased lactate production even in the presence of sufficient oxygen... 
NMR | Metabolic flux | Hyperglycemia | Proximal tubule cells | Hyperpolarized [1-13C]pyruvate | Oxamate | Hyperpolarized [1 | C]pyruvate | METFORMIN | ACTIVATION | FLUX | HYPOXIA | CELL BIOLOGY | Hyperpolarized [1-C-13]pyruvate | ONCOLOGY | PYRUVATE-CARBOXYLASE | DISEASE | Glucose metabolism | Endothelial growth factors | Physiological aspects | Kidney diseases | Glucose | Cells | Dextrose
Journal Article
Journal of Magnetic Resonance, ISSN 1090-7807, 10/2018, Volume 295, pp. 63 - 71
Hyperpolarized (HP) Xe MRI is emerging as a powerful, non-invasive method to image lung function and is beginning to find clinical application across a range... 
Hyperpolarized 129Xe | Ventilator | Preclinical | Rodent | MRI | Lung | Hyperpolarized | lung | ventilator | preclinical | rodent
Journal Article
Journal of Magnetic Resonance, ISSN 1090-7807, 09/2019, Volume 306, pp. 124 - 127
Hyperpolarized MR by dissolution Dynamic Nuclear Polarization (dDNP) appeared on the scene in 2003. Since then, it has been translated to the clinic and... 
Dissolution-DNP | Hyperpolarization | Hyperpolarized MR
Journal Article
Journal of Applied Physiology, ISSN 8750-7587, 07/2018, Volume 125, Issue 1, pp. 73 - 85
Journal Article
Magnetic Resonance in Medicine, ISSN 0740-3194, 07/2007, Volume 58, Issue 1, pp. 65 - 69
We present for the first time dynamic spectra and spectroscopic images acquired in normal rats at 3T following the injection of 13C‐1‐pyruvate that was... 
hyperpolarized 13C | spectroscopic imaging | pyruvate | in vivo metabolism | chemical shift imaging | In vivo metabolism | Pyruvate | Hyperpolarized | Spectroscopic imaging | Chemical shift imaging
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 02/2019, Volume 131, pp. 18 - 26
Effective means to identify the role of reactive oxygen species (ROS) mediating several diseases including cancer, ischemic heart disease, stroke, Alzheimer's... 
DMPO: reactive oxygen species | Hyperpolarized 13C-MRI | Spin trapping | Hyperpolarized | C-MRI
Journal Article
Progress in Nuclear Magnetic Resonance Spectroscopy, ISSN 0079-6565, 2009, Volume 55, Issue 4, pp. 285 - 295
The new era of Molecular Imaging can be defined as the visual representation, characterization and quantification of biological processes at the cellular and... 
Molecular imaging | Pyruvate | Metabolic imaging | Dynamic nuclear polarization | Hyperpolarized 13C | Hyperpolarized
Journal Article
Academic Radiology, ISSN 1076-6332, 12/2014, Volume 21, Issue 12, pp. 1530 - 1541
Clinical deployment of hyperpolarized Xe magnetic resonance imaging requires accurate quantification and visualization of the ventilation defect percentage... 
ventilation defect analysis | Hyperpolarized 129Xe MRI | lung segmentation | image registration | Xe MRI | Lung segmentation | Image registration | Hyperpolarized | Ventilation defect analysis
Journal Article
Magnetic Resonance in Medicine, ISSN 0740-3194, 08/2011, Volume 66, Issue 2, pp. 505 - 519
Dynamic nuclear polarization is an emerging technique for increasing the sensitivity of magnetic resonance imaging and spectroscopy, particularly for low‐γ... 
dynamic nuclear polarization | metabolism | hyperpolarized carbon‐13 | imaging | pyruvate | tumor | hyperpolarized carbon-13 | Neoplasms - metabolism | Magnetic Resonance Spectroscopy - methods | Biomarkers, Tumor - analysis | Humans | Carbon Isotopes | Magnetic Resonance Imaging - methods | Neoplasms - diagnosis | Radiopharmaceuticals
Journal Article