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Journal of allergy and clinical immunology, ISSN 0091-6749, 02/2013, Volume 131, Issue 2, pp. 549 - 561
Background Allergic rhinitis (AR) and asthma are 2 entities of allergic airway diseases that frequently occur together, which is referred to as united airways... 
Allergy and Immunology | pathogen associated molecular pattern | allergic asthma | innate immunity | house dust mite | Allergic rhinitis | reactive oxygen species | epithelium | β-glucans | dual oxidase 2 | Toll-like receptor | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Asthma - metabolism | Epithelial Cells - metabolism | Reactive Oxygen Species - metabolism | Rhinitis, Allergic | NADPH Oxidases - metabolism | Hypersensitivity - immunology | NADPH Oxidases - immunology | Lipopolysaccharides - immunology | Rhinitis, Allergic, Perennial - metabolism | Hypersensitivity - metabolism | Reactive Oxygen Species - immunology | Respiratory Mucosa - immunology | Asthma - immunology | Lung - metabolism | Nasal Mucosa - metabolism | beta-Glucans - immunology | Respiratory System - immunology | Rhinitis, Allergic, Perennial - immunology | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 4 - metabolism | Immunity, Innate - immunology | beta-Glucans - metabolism | Animals | Nasal Mucosa - immunology | Respiratory System - metabolism | Epithelial Cells - immunology | Toll-Like Receptor 2 - immunology | Mice | Respiratory Mucosa - metabolism | Dual Oxidases | Lung - immunology | Pyroglyphidae - immunology | Medical colleges | Asthma | Lipids | Gene expression | Allergies | Immune system | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2013, Volume 131, Issue 6, pp. 1653 - 1662.e1
Background DJ-1 is an antioxidant protein known to reduce levels of reactive oxygen species (ROS), but its presence or function in mast cells and allergic... 
Allergy and Immunology | FcεRI-mediated signals | allergy | DJ-1 | mast cells | reactive oxygen species | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - metabolism | Tumor Necrosis Factor-alpha - metabolism | Oncogene Proteins - blood | Oncogene Proteins - genetics | Phosphorylation | Reactive Oxygen Species - metabolism | Protein-Tyrosine Kinases - metabolism | Humans | Middle Aged | Child, Preschool | Male | Intracellular Signaling Peptides and Proteins - metabolism | Phosphoproteins - metabolism | Young Adult | RNA Interference | Bone Marrow Cells - immunology | Dermatitis, Atopic - immunology | Mast Cells - metabolism | Hypersensitivity, Immediate - immunology | Adult | Female | Membrane Proteins - metabolism | Child | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | Disease Models, Animal | Mast Cells - immunology | Signal Transduction | Interleukin-4 - metabolism | Hypersensitivity, Immediate - genetics | Oncogene Proteins - metabolism | Cell Degranulation - immunology | Intracellular Signaling Peptides and Proteins - blood | Mice, Knockout | Passive Cutaneous Anaphylaxis | Protein Deglycase DJ-1 | Animals | Proto-Oncogene Proteins c-fyn - metabolism | Hypersensitivity, Immediate - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Receptors, IgE - metabolism | Adolescent | Antigens - immunology | Mice | Adaptor Proteins, Signal Transducing - metabolism | Dermatitis, Atopic - metabolism | Bone Marrow Cells - metabolism | Cytokines - biosynthesis | Antioxidants | Immunoglobulin E | Drugstores | Medical colleges | Proteins | Histamine | Disease | Phosphatase | Allergies | Asthma | Index Medicus | Abridged Index Medicus | reactive oxygen species (ROS)
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 12/2010, Volume 107, Issue 52, pp. 22617 - 22622
Immune cells take residence in metabolic tissues, providing a framework for direct regulation of nutrient metabolism... 
Obesity | Hepatocytes | Liver | Insulin resistance | Mice | Gene expression regulation | Inflammation | Lipid metabolism | Insulin | Fatty acids | Cytokines | Th2 immunity | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Adipocytes - cytology | Immunoblotting | Male | Muscle, Skeletal - metabolism | STAT6 Transcription Factor - genetics | Adipocytes - drug effects | Hepatocytes - metabolism | Adipose Tissue - metabolism | Hepatocytes - cytology | Interleukin-4 - pharmacology | Liver - drug effects | Insulin Resistance - physiology | Muscle, Skeletal - drug effects | Dietary Fats - administration & dosage | Female | Obesity - etiology | Phosphorylation - drug effects | Hepatocytes - drug effects | Cell Line | Dietary Fats - adverse effects | Liver - metabolism | Mice, Inbred C57BL | Cells, Cultured | Obesity - physiopathology | STAT6 Transcription Factor - metabolism | 3T3-L1 Cells | Mice, Knockout | Obesity - metabolism | Animals | Signal Transduction - drug effects | Adipocytes - metabolism | Mice, Inbred BALB C | PPAR alpha - metabolism | Adipose Tissue - drug effects | Energy Metabolism - drug effects | Care and treatment | Physiological aspects | Research | Properties | Biological control systems | Index Medicus | Adipose tissue | Transcription | Oxidative metabolism | Hypersensitivity | Conservation | Homeostasis | Glucose | Coevolution | Immunity | Infection | Interleukin 4 | Stat6 protein | Evolution | Nutrients | Peroxisome proliferator-activated receptors | Immune system | Biological Sciences | cytokines | liver | insulin resistance | obesity
Journal Article
The American journal of pathology, ISSN 0002-9440, 2011, Volume 179, Issue 1, pp. 248 - 258
Journal Article
Journal Article
Journal of Applied Physiology, ISSN 1522-1601, 10/2009, Volume 107, Issue 4, pp. 1285 - 1292
We showed recently that IL-4 causes mitochondrial dysfunction in allergic asthma. IL-4 is also known to induce 12/15-lipoxygenase (12/15-LOX), a potent... 
Mitochondria | 12/15-lipoxygenase | Physiology | Sport Sciences | Life Sciences & Biomedicine | Science & Technology | Bronchial Hyperreactivity - immunology | Hyperplasia | Transforming Growth Factor beta1 - metabolism | Hypersensitivity - immunology | Male | Mitochondria - immunology | Hypersensitivity - drug therapy | Immunoglobulin E - blood | Electron Transport Complex IV - metabolism | Asthma - immunology | Disease Models, Animal | 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid - metabolism | Anti-Asthmatic Agents - pharmacology | Asthma - physiopathology | Lung - physiopathology | Pulmonary Fibrosis - pathology | Interleukin-13 - metabolism | Linoleic Acids - metabolism | Bronchial Hyperreactivity - pathology | Hypersensitivity - physiopathology | Hypersensitivity - pathology | Lung - drug effects | Mice | Mice, Inbred BALB C | Oxidative Stress - drug effects | Asthma - pathology | Vitamin E - pharmacology | Asthma - metabolism | Arachidonate 12-Lipoxygenase - metabolism | Bronchial Hyperreactivity - drug therapy | Bronchial Provocation Tests | Goblet Cells - drug effects | Mitochondria - ultrastructure | Hypersensitivity - metabolism | Bronchial Hyperreactivity - physiopathology | Lung - ultrastructure | Bronchial Hyperreactivity - metabolism | Lung - metabolism | Ovalbumin | Interleukin-5 - metabolism | Cytochromes c - metabolism | Interleukin-4 - metabolism | Mitochondria - metabolism | Mitochondria - drug effects | Arachidonate 15-Lipoxygenase - metabolism | Asthma - drug therapy | Animals | Airway Remodeling - drug effects | Goblet Cells - pathology | Pulmonary Fibrosis - drug therapy | Lung - immunology | Index Medicus | Innovative Methodologies | mitochondria | 15-lipoxygenase
Journal Article