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Hepatology, ISSN 0270-9139, 04/2014, Volume 59, Issue 4, pp. 1492 - 1504
Journal Article
Journal Article
The FEBS Journal, ISSN 1742-464X, 01/2017, Volume 284, Issue 1, pp. 114 - 133
Portal hypertension is a frequent pathological symptom occurring especially in hepatic fibrosis and cirrhosis. Current paradigms indicate that inhibition of... 
contraction | hepatic stellate cell | portal hypertension | dihydroartemisinin | farnesoid X receptor | APOPTOSIS | ACTIVATION | OBETICHOLIC ACID | SAFETY | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIVER FIBROSIS | RATS | PATHWAY | INFLAMMATION | CIRRHOSIS | EXPRESSION | Hypertension, Portal - genetics | Liver - pathology | Carbon Tetrachloride | Humans | Hepatic Stellate Cells - metabolism | Hepatocytes - pathology | Male | Hepatocytes - metabolism | Hypertension, Portal - chemically induced | Liver Cirrhosis - chemically induced | Hypertension, Portal - prevention & control | Artemisinins - pharmacology | Liver - drug effects | Protective Agents - pharmacology | Chenodeoxycholic Acid - pharmacology | Cell Death - drug effects | Liver Cirrhosis - genetics | Hepatic Stellate Cells - pathology | Hepatocytes - drug effects | Hepatic Stellate Cells - drug effects | Liver Cirrhosis - drug therapy | Gene Expression | Portal Vein - drug effects | Hypertension, Portal - pathology | Liver - metabolism | Rats | Mice, Transgenic | Receptors, Cytoplasmic and Nuclear - agonists | Receptors, Cytoplasmic and Nuclear - genetics | Rats, Sprague-Dawley | Chenodeoxycholic Acid - analogs & derivatives | Mice, Inbred ICR | Liver - blood supply | Animals | Pregnenediones - pharmacology | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Liver Cirrhosis - pathology | Mice | Receptors, Cytoplasmic and Nuclear - metabolism | Analysis | Venous pressure | Portal hypertension | Hypertension | Rodents | Bile | Dihydroartemisinin | Carbon tetrachloride | Liver | Contractility | Activation | Inflammation | Contraction | Cirrhosis | Cell activation | Injury prevention | Fibrosis | Extracellular matrix | Infiltration | Inhibition | Portal vein | Immunofluorescence
Journal Article
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2008, Volume 118, Issue 12, pp. 3980 - 3989
Environmental arsenic exposure, through drinking contaminated water, is a significant risk factor for developing vascular diseases and is associated with liver... 
Free Radical Scavengers - pharmacology | Hypertension, Portal - genetics | Liver - pathology | Liver - enzymology | Platelet Endothelial Cell Adhesion Molecule-1 - genetics | Membrane Glycoproteins - metabolism | NADPH Oxidases - metabolism | rac GTP-Binding Proteins - metabolism | Arsenic - toxicity | Liver Cirrhosis - enzymology | Hypertension, Portal - chemically induced | Hypertension, Portal - enzymology | Liver Cirrhosis - chemically induced | Neovascularization, Pathologic - pathology | Cell Differentiation - genetics | Neovascularization, Pathologic - enzymology | Platelet Endothelial Cell Adhesion Molecule-1 - metabolism | rac GTP-Binding Proteins - genetics | Superoxides - metabolism | NADPH Oxidases - genetics | Neuropeptides - genetics | Liver Cirrhosis - genetics | Gene Expression Regulation - genetics | Hypertension, Portal - pathology | Cells, Cultured | Neuropeptides - metabolism | Neovascularization, Pathologic - chemically induced | NADPH Oxidase 2 | Membrane Glycoproteins - genetics | Mice, Knockout | Gene Expression Regulation - drug effects | Liver - blood supply | Animals | Water Pollutants, Chemical - toxicity | Cell Differentiation - drug effects | Liver Cirrhosis - pathology | Neovascularization, Pathologic - genetics | Mice | rac1 GTP-Binding Protein | Endothelial Cells - pathology | Endothelial Cells - enzymology | Oxidases | Physiological aspects | Active oxygen | Arsenic | Health aspects | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Gut, ISSN 0017-5749, 10/2007, Volume 56, Issue 10, pp. 1404 - 1409
Journal Article
World Journal of Gastroenterology, ISSN 1007-9327, 04/2015, Volume 21, Issue 15, pp. 4509 - 4516
Journal Article
世界胃肠病学杂志:英文版, ISSN 1007-9327, 2015, Volume 21, Issue 32, pp. 9544 - 9553
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 08/2017, Volume 329, pp. 224 - 230
Serotonin (5-HT) has been implicated as a key driver of liver fibrosis, acting via 5-HT2 receptor activation in the hepatic stellate cells. The current study... 
Mirtazapine | Extracellular signal regulated kinase 1 and 2 | 5-HT2A receptor | Smad | Transforming growth factor-β1 | 5-HT | OXIDATIVE STRESS | RECEPTOR ANTAGONISTS | LIVER FIBROSIS | BETA | HEPATIC STELLATE CELLS | REACTIVE OXYGEN | MESANGIAL CELLS | PHARMACOLOGY & PHARMACY | SEROTONIN | TOXICOLOGY | EXPRESSION | PULMONARY-FIBROSIS | Transforming growth factor-f beta | Liver - pathology | Phosphorylation | Glutathione - metabolism | Transforming Growth Factor beta1 - metabolism | Hepatic Stellate Cells - metabolism | Male | Smad3 Protein - metabolism | Hypertension, Portal - chemically induced | Hypertension, Portal - prevention & control | Mianserin - analogs & derivatives | Mianserin - pharmacology | Liver Cirrhosis, Experimental - prevention & control | Liver - drug effects | Protein Kinase C - metabolism | Lipid Peroxidation - drug effects | Liver Cirrhosis, Experimental - pathology | Receptor, Serotonin, 5-HT2A - drug effects | NADH, NADPH Oxidoreductases - metabolism | Hepatic Stellate Cells - pathology | Hepatic Stellate Cells - drug effects | Liver - metabolism | Antioxidants - pharmacology | Serotonin 5-HT2 Receptor Antagonists - pharmacology | NADPH Oxidase 1 | Collagen - metabolism | Thioacetamide | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Signal Transduction - drug effects | Hypertension, Portal - metabolism | Liver Cirrhosis, Experimental - chemically induced | Serotonin - metabolism | Mice | Oxidative Stress - drug effects | Receptor, Serotonin, 5-HT2A - metabolism | Liver Cirrhosis, Experimental - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism | Index Medicus | FIBROSIS | BLOOD PRESSURE | LIVER | SIGNALS | PHOSPHOTRANSFERASES | MICE | 60 APPLIED LIFE SCIENCES | PLANT GROWTH
Journal Article