X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2540) 2540
Publication (488) 488
Book Chapter (88) 88
Book Review (30) 30
Dissertation (9) 9
Book / eBook (6) 6
Government Document (2) 2
Conference Proceeding (1) 1
Magazine Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (1349) 1349
hypocretin (1308) 1308
index medicus (1279) 1279
neurosciences (1255) 1255
orexins (1205) 1205
male (1016) 1016
orexin (1008) 1008
humans (908) 908
narcolepsy (860) 860
sleep (830) 830
neurons (773) 773
rats (662) 662
hypothalamus (566) 566
hypocretin orexin (540) 540
clinical neurology (473) 473
female (473) 473
neuropeptides - metabolism (450) 450
mice (406) 406
orexin receptors (372) 372
brain (361) 361
cataplexy (357) 357
intracellular signaling peptides and proteins - metabolism (347) 347
neurons - metabolism (323) 323
neurology (312) 312
pharmacology & pharmacy (305) 305
nervous system (304) 304
rat-brain (288) 288
rats, sprague-dawley (287) 287
intracellular signaling peptides and proteins (276) 276
peptides (274) 274
adult (258) 258
article (256) 256
arousal (249) 249
melanin-concentrating hormone (248) 248
neuropeptides (245) 245
orexin/hypocretin (241) 241
rat (232) 232
sleep - physiology (227) 227
wakefulness (225) 225
neuropeptides - physiology (210) 210
sleep disorders (209) 209
middle aged (207) 207
physiology (206) 206
mental disorders (205) 205
neuropeptides - pharmacology (205) 205
psychiatry (205) 205
biochemistry & molecular biology (204) 204
hypothalamus - metabolism (203) 203
rats, wistar (202) 202
lateral hypothalamus (199) 199
endocrinology & metabolism (198) 198
neurons - physiology (194) 194
wakefulness - physiology (194) 194
neurons - drug effects (191) 191
immunohistochemistry (188) 188
hypocretins (184) 184
psychological phenomena and processes (179) 179
expression (177) 177
analysis (172) 172
ventral tegmental area (172) 172
neuropeptides - genetics (171) 171
neuropeptide-y (168) 168
food-intake (163) 163
physiological aspects (163) 163
intracellular signaling peptides and proteins - physiology (161) 161
rem-sleep (160) 160
narcolepsy - physiopathology (159) 159
orexin-a (156) 156
hypocretin/orexin (155) 155
receptors, neuropeptide - metabolism (154) 154
receptors (149) 149
dose-response relationship, drug (142) 142
rodents (142) 142
mice, inbred c57bl (141) 141
system (141) 141
behavior (139) 139
activation (136) 136
dopamine (135) 135
receptors, g-protein-coupled (133) 133
messenger-rna (130) 130
orexin/hypocretin neurons (130) 130
reward (128) 128
research (127) 127
aged (125) 125
urea - analogs & derivatives (124) 124
locus-coeruleus (121) 121
intracellular signaling peptides and proteins - pharmacology (120) 120
obesity (120) 120
feeding-behavior (119) 119
human narcolepsy (117) 117
behavioral sciences (116) 116
digestive, oral, and skin physiology (114) 114
receptor (114) 114
hypocretin neurons (112) 112
orexins - metabolism (112) 112
adolescent (110) 110
disease models, animal (110) 110
intracellular signaling peptides and proteins - genetics (110) 110
canine narcolepsy (109) 109
stress (109) 109
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2543) 2543
German (19) 19
French (15) 15
Spanish (14) 14
Japanese (12) 12
Polish (6) 6
Chinese (4) 4
Czech (4) 4
Italian (2) 2
Russian (2) 2
Slovak (2) 2
Portuguese (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


11/2010
The role of hypocretin neurons in modulating somatic motoneuron excitability and hence muscle tone is poorly understood. We investigated whether hypocretin... 
Hypocretin | 0317
Dissertation
Neuropsychopharmacology, ISSN 0893-133X, 09/2012, Volume 37, Issue 10, pp. 2210 - 2221
Growing evidence indicates that an increase of orexin (or hypocretin) signaling is involved in the pathophysiology of major depression, but little is known... 
hypothalamic-pituitary-adrenal axis | orexin/hypocretin | depression | antidepressant | dual orexin/hypocretin receptor antagonist | hippocampal neurogenesis | ADULT HIPPOCAMPUS | PSYCHIATRY | CHRONIC MILD STRESS | CELL-PROLIFERATION | OREXIN/HYPOCRETIN NEURONS | REWARD-SEEKING | MAJOR DEPRESSION | CEREBROSPINAL-FLUID | NEUROSCIENCES | PHARMACOLOGY & PHARMACY | ANIMAL-MODEL | RAT-BRAIN | Cell Proliferation | Neuropeptides - physiology | Depression - drug therapy | Acetamides - therapeutic use | Behavior, Animal - drug effects | Fluoxetine - therapeutic use | Disease Models, Animal | Neuropeptides - analysis | Hypothalamo-Hypophyseal System - drug effects | Microtubule-Associated Proteins - analysis | Orexins | Pituitary-Adrenal System - drug effects | Receptors, Neuropeptide - antagonists & inhibitors | Orexin Receptors | Antidepressive Agents - therapeutic use | Animals | Ki-67 Antigen - analysis | Neurogenesis - physiology | Bromodeoxyuridine - analysis | Receptors, G-Protein-Coupled - antagonists & inhibitors | Biomarkers | Isoquinolines - therapeutic use | Mice | Mice, Inbred BALB C | Intracellular Signaling Peptides and Proteins - physiology | Cell proliferation | Neonates | Animal models | Dexamethasone | Fluoxetine | Bromodeoxyuridine | Depression | Hypothalamic-pituitary-adrenal axis | Neurogenesis | Stress | Antidepressants | Feedback | Orexin receptors | Doublecortin protein | Hippocampus | animal models | dual orexin | hypocretin receptor antagonist | neuropeptides | unipolar | psychopharmacology | hypocretin | bipolar | orexin | Original
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 07/2012, Volume 37, Issue 8, pp. 1911 - 1922
Journal Article
Sleep, ISSN 0161-8105, 10/2018, Volume 41, Issue 10
Study Objectives: The present study investigated the function of Hypocretin (Hcrt or Orexin/OX) receptor antagonists in sleep modulation and memory function... 
fiber photometry | memory | orexin/hypocretin receptor antagonist | EEG spectral analysis | optogenetics | sleep pattern | SUVOREXANT | SLEEP-DEPRIVATION | NEUROSCIENCES | DISCOVERY | CLINICAL NEUROLOGY | HYPOCRETIN OREXIN | NARCOLEPSY | ZOLPIDEM | ESZOPICLONE | NEURONS | orexin/ hypocretin receptor antagonist | REM-SLEEP
Journal Article
Brain Research, ISSN 0006-8993, 2018
The orexin system includes the neuropeptides orexin A and B and the cognate receptors of orexin-1 (OX1) and -2 (OX2) and has been indicated in a number of... 
Antagonist | Addiction | Selective | Hypocretin | Orexin
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2017, Volume 114, Issue 27, pp. E5464 - E5473
Journal Article
Neuropharmacology, ISSN 0028-3908, 08/2019, Volume 154, pp. 68 - 78
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 02/2018, Volume 38, Issue 6, pp. 1588 - 1599
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 06/2013, Volume 110, Issue 24, pp. E2229 - E2238
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 11/2018, Volume 104, Issue 5, pp. 1022 - 1029
The orexin system regulates sleep and arousal and is targeted by ACT‐541468, a new dual orexin receptor antagonist (DORA). Healthy male subjects received a... 
SYSTEM | DRUG | SUVOREXANT | INSOMNIA | SLEEP | OREXIN/HYPOCRETIN | SAFETY | HYPOCRETIN | PHARMACOLOGY & PHARMACY | HEALTHY-VOLUNTEERS | ALMOREXANT
Journal Article
BRAIN RESEARCH, ISSN 0006-8993, 05/2011, Volume 1391, pp. 54 - 59
A role for orexin A in mediating the primary and conditioned reinforcing effects of alcohol has been established. It is unclear however whether the... 
SYSTEM | Self-administration | Ethanol | Sucrose | INDUCED REINSTATEMENT | HYPOCRETIN | SB-334867 | NEUROSCIENCES | Orexin/Hypocretin | PEPTIDES | Motivation | NEURONS | SEEKING | SCHEDULES
Journal Article