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Diabetes Care, ISSN 0149-5992, 2014, Volume 37, Issue 5, pp. 1338 - 1345
Journal Article
1969, Medicinal chemistry; a series of monographs, v. 9, 482
Book
Journal Article
Phytomedicine, ISSN 0944-7113, 2007, Volume 14, Issue 1, pp. 15 - 22
Journal Article
Journal Article
Journal of Biochemical and Molecular Toxicology, ISSN 1095-6670, 09/2018, Volume 32, Issue 9, pp. e22197 - n/a
[Ni(C 11 H 9 N 2 O 5 ) 2 (H 2 O) 2 ]•3(C 3 H 7 NO) ( 1 ) and [Co(C 11 H 9 N 2 O 5 ) 2 (H 2 O) 2 ]•3(C 3 H 7 NO) ( 2 ) are synthesized and characterized by... 
synthesis | crystal structure | magnetic properties | enzyme inhibition | N‐salicyloil‐N’‐maleoil‐hydrazine | N-salicyloil-N’-maleoil-hydrazine | BIOACTIVITY | BUTYRYLCHOLINESTERASE | N-salicyloil-N'-maleoil-hydrazine | PROFILES | CARBONIC-ANHYDRASE ISOENZYMES | BIOCHEMISTRY & MOLECULAR BIOLOGY | II INHIBITION | ACETYLCHOLINESTERASE | ALPHA-GLUCOSIDASE INHIBITORS | TOXICOLOGY | DERIVATIVES | BROMOPHENOLS | MANNICH-BASES | Cholinergic Antagonists - chemical synthesis | Humans | Cholinesterase Inhibitors - chemistry | Carbonic Anhydrase II - metabolism | Crystallography, X-Ray | Cholinesterase Inhibitors - chemical synthesis | Carbonic Anhydrase I - metabolism | Enzyme Inhibitors - chemical synthesis | Spectroscopy, Fourier Transform Infrared | Carbonic Anhydrase II - antagonists & inhibitors | Cholinergic Antagonists - pharmacology | Hydrazines - chemistry | Hydrazines - chemical synthesis | Butyrylcholinesterase - chemistry | Cobalt - pharmacology | Proton Magnetic Resonance Spectroscopy | Butyrylcholinesterase - metabolism | Magnetic Phenomena | Enzyme Inhibitors - chemistry | Carbon-13 Magnetic Resonance Spectroscopy | Coordination Complexes - pharmacology | Molecular Structure | Nickel - pharmacology | Glycoside Hydrolases - antagonists & inhibitors | Hydrazines - pharmacology | Nickel - chemistry | Enzyme Inhibitors - pharmacology | Hypoglycemic Agents - chemistry | Acetylcholinesterase - chemistry | Carbonic Anhydrase I - chemistry | Coordination Complexes - chemistry | Hypoglycemic Agents - pharmacology | Animals | Cholinesterase Inhibitors - pharmacology | Carbonic Anhydrase I - antagonists & inhibitors | Cholinergic Antagonists - chemistry | Hypoglycemic Agents - chemical synthesis | Glycoside Hydrolases - metabolism | Acetylcholinesterase - metabolism | Cobalt - chemistry | Infrared spectroscopy | Hydrazines | Water chemistry | Oxygen | Diabetes mellitus | Nitrogen atoms | Acetylcholinesterase | Magnetic susceptibility | Oxygen atoms | Carbonic anhydrase | Magnetic permeability | Isoforms | Acetylcholine receptors | Nickel | Thermal analysis | Hydrazine | Crystal structure | Metal ions | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2012, Volume 122, Issue 4, pp. 1339 - 1353
Defective brain insulin signaling has been suggested to contribute to the cognitive deficits in patients with Alzheimer's disease (AD). Although a connection... 
MAMMALIAN TARGET | MEDICINE, RESEARCH & EXPERIMENTAL | INTRANASAL INSULIN | RECEPTOR-DEPENDENT MECHANISM | AMYLOID-BETA | AXONAL-TRANSPORT | TNF-ALPHA | SYNAPTIC PLASTICITY | CULTURED HIPPOCAMPAL-NEURONS | PEPTIDE OLIGOMERS | TRANSGENIC MICE | Phosphorylation | Insulin - physiology | Humans | Middle Aged | Macaca fascicularis | Memory Disorders - metabolism | Male | Hippocampus - drug effects | Insulin Receptor Substrate Proteins - metabolism | Infliximab | Alzheimer Disease - prevention & control | Aged, 80 and over | Female | Neurons - metabolism | Neurons - drug effects | Alzheimer Disease - psychology | Hypoglycemic Agents - therapeutic use | Cells, Cultured - drug effects | Amyloid beta-Peptides - toxicity | Antibodies, Monoclonal - pharmacology | Mice, Inbred C57BL | Insulin Resistance | Rats | Mice, Transgenic | Hippocampus - pathology | Hippocampus - cytology | Maze Learning - drug effects | Hypoglycemic Agents - pharmacology | Peptides - pharmacology | Hippocampus - metabolism | Memory Disorders - prevention & control | Animals | MAP Kinase Signaling System - drug effects | Memory Disorders - etiology | Alzheimer Disease - metabolism | Venoms - therapeutic use | Aged | Cells, Cultured - metabolism | Mice | Protein Processing, Post-Translational | Venoms - pharmacology | Alzheimer Disease - genetics | Peptides - therapeutic use | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Journal of Pharmacy and Pharmacology, ISSN 0022-3573, 04/2013, Volume 65, Issue 4, pp. 591 - 603
This study was carried out to assess the anti-obesity effect of Hypericum silenoides Juss. and Hypericum philonotis Cham. & Schlecht. in male Wistar rats fed... 
anti‐obesity natural products | tlanchalagua | cafeteria diet | ypericum philonotis | ypericum silenoides | Hypericum philonotis | anti-obesity natural products | Hypericum silenoides | Obesity - drug therapy | Rats, Wistar | Plant Extracts - pharmacology | Male | Obesity - blood | Anti-Obesity Agents - therapeutic use | Antidepressive Agents - isolation & purification | Depression - etiology | Dose-Response Relationship, Drug | Enzyme Inhibitors - administration & dosage | Plant Extracts - administration & dosage | Hypoglycemic Agents - administration & dosage | Lipase - antagonists & inhibitors | Hypericum - growth & development | Antidepressive Agents - pharmacology | Plant Components, Aerial - growth & development | Hypoglycemic Agents - therapeutic use | Hyperglycemia - prevention & control | Anti-Obesity Agents - administration & dosage | Plant Components, Aerial - chemistry | Enzyme Inhibitors - pharmacology | Hypolipidemic Agents - isolation & purification | Rats | Obesity - physiopathology | Plant Extracts - isolation & purification | Random Allocation | Hypolipidemic Agents - pharmacology | Enzyme Inhibitors - therapeutic use | Hyperlipidemias - prevention & control | Anti-Obesity Agents - isolation & purification | Enzyme Inhibitors - isolation & purification | Hypoglycemic Agents - pharmacology | Antidepressive Agents - therapeutic use | Hypoglycemic Agents - isolation & purification | Ethnopharmacology | Animals | Depression - prevention & control | Hyperlipidemias - etiology | Hypolipidemic Agents - administration & dosage | Antidepressive Agents - administration & dosage | Mexico | Hyperglycemia - etiology | Hypolipidemic Agents - therapeutic use | Medicine, Traditional | Anti-Obesity Agents - pharmacology | Plant Extracts - therapeutic use | Hypericum - chemistry | Index Medicus
Journal Article
Food and Function, ISSN 2042-6496, 3/2015, Volume 6, Issue 3, pp. 834 - 841
The present study investigated the anti-obesity and anti-diabetic effects of kaempferol glycoside (KG) fractions which were composed of four kaempferol... 
ENERGY-BALANCE | QUERCETIN | CELLS | OBESITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOOD SCIENCE & TECHNOLOGY | GLUCOSIDES | KINASE | ALPHA | ABSORPTION | Glycated Hemoglobin A - analysis | Humans | Male | Anti-Obesity Agents - therapeutic use | Dietary Supplements - analysis | Soybeans - growth & development | Glycosides - isolation & purification | Kaempferols - isolation & purification | Diabetes Mellitus, Type 2 - etiology | Obesity - etiology | Hypolipidemic Agents - chemistry | Kaempferols - analysis | Glycosides - chemistry | Hypoglycemic Agents - therapeutic use | Hypolipidemic Agents - analysis | Kaempferols - chemistry | Obesity - complications | Diabetes Mellitus, Type 2 - prevention & control | Hypolipidemic Agents - isolation & purification | Lipid Metabolism | Plant Extracts - isolation & purification | Random Allocation | Hypoglycemic Agents - isolation & purification | Soybeans - chemistry | Anti-Obesity Agents - chemistry | Plant Leaves - growth & development | Obesity - prevention & control | Hypolipidemic Agents - therapeutic use | Plant Extracts - therapeutic use | Plant Extracts - chemistry | Hypoglycemic Agents - analysis | Diet, High-Fat - adverse effects | Anti-Obesity Agents - analysis | Kaempferols - therapeutic use | Diabetes Mellitus, Type 2 - metabolism | Adiposity | Diabetes Mellitus, Type 2 - complications | Plant Leaves - chemistry | Glycosides - analysis | Mice, Inbred C57BL | Insulin Resistance | Hypertriglyceridemia - metabolism | Hypoglycemic Agents - chemistry | Anti-Obesity Agents - isolation & purification | Obesity - metabolism | Hypertriglyceridemia - prevention & control | Animals | Hypertriglyceridemia - complications | Hypertriglyceridemia - etiology | Glycosides - therapeutic use | Index Medicus
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 11/2013, Volume 15, Issue 11, pp. 1040 - 1048
AimsPostprandial triglyceridaemia is a risk factor for cardiovascular disease (CVD). This study investigated the effects of steady-state liraglutide 1.8mg... 
lipid‐lowering therapy | study | randomized trial | 1 analogue | antidiabetic drug | GLP | phase I | type | diabetes | Type II diabetes | Randomized trial | Antidiabetic drug | Lipid-lowering therapy | GLP-1 analogue | Phase I-II study | LIPEMIA | OXIDATIVE STRESS | RECEPTOR AGONISTS | EXENATIDE | ACID BREATH TEST | INSULIN RESPONSES | MELLITUS | type II diabetes | lipid-lowering therapy | phase I-II study | THERAPY | GLUCOSE | ENDOCRINOLOGY & METABOLISM | GLUCAGON | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Diet, High-Fat - adverse effects | Half-Life | Glucagon-Like Peptide 1 - blood | Male | Hypoglycemic Agents - blood | Cardiovascular Diseases - complications | Hypolipidemic Agents - blood | Lipids - blood | Postprandial Period | Cardiovascular Diseases - epidemiology | Female | Glucagon-Like Peptide 1 - pharmacokinetics | Diabetes Mellitus, Type 2 - complications | Hyperlipidemias - complications | Body Mass Index | Hypoglycemic Agents - therapeutic use | Hypolipidemic Agents - adverse effects | Hypoglycemic Agents - pharmacokinetics | Double-Blind Method | Glucagon-Like Peptide 1 - analogs & derivatives | Obesity - complications | Risk Factors | Hyperlipidemias - prevention & control | Germany - epidemiology | Cross-Over Studies | Diabetes Mellitus, Type 2 - blood | Gastric Emptying - drug effects | Hyperlipidemias - etiology | Denmark - epidemiology | Aged | Hypolipidemic Agents - therapeutic use | Diabetes Mellitus, Type 2 - drug therapy | Glucagon-Like Peptide 1 - adverse effects | Hypolipidemic Agents - pharmacokinetics | Hypoglycemic Agents - adverse effects | Liraglutide | Glucagon-Like Peptide 1 - therapeutic use | Type 2 diabetes | Care and treatment | Low density lipoproteins | Anticholesteremic agents | Clinical trials | Triglycerides | Glucose | Fatty acids | Cholesterol | Dextrose | Glucose metabolism | Hypoglycemic agents | Diabetes therapy | Lipids | Diet | Apolipoproteins | Index Medicus
Journal Article