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Journal Article
Chemical Communications, ISSN 1359-7345, 05/2014, Volume 50, Issue 40, pp. 5248 - 5250
Journal Article
Journal of Biochemical and Molecular Toxicology, ISSN 1095-6670, 09/2018, Volume 32, Issue 9, pp. e22197 - n/a
[Ni(C 11 H 9 N 2 O 5 ) 2 (H 2 O) 2 ]•3(C 3 H 7 NO) ( 1 ) and [Co(C 11 H 9 N 2 O 5 ) 2 (H 2 O) 2 ]•3(C 3 H 7 NO) ( 2 ) are synthesized and characterized by... 
synthesis | crystal structure | magnetic properties | enzyme inhibition | N‐salicyloil‐N’‐maleoil‐hydrazine | N-salicyloil-N’-maleoil-hydrazine | BIOACTIVITY | BUTYRYLCHOLINESTERASE | N-salicyloil-N'-maleoil-hydrazine | PROFILES | CARBONIC-ANHYDRASE ISOENZYMES | BIOCHEMISTRY & MOLECULAR BIOLOGY | II INHIBITION | ACETYLCHOLINESTERASE | ALPHA-GLUCOSIDASE INHIBITORS | TOXICOLOGY | DERIVATIVES | BROMOPHENOLS | MANNICH-BASES | Cholinergic Antagonists - chemical synthesis | Humans | Cholinesterase Inhibitors - chemistry | Carbonic Anhydrase II - metabolism | Crystallography, X-Ray | Cholinesterase Inhibitors - chemical synthesis | Carbonic Anhydrase I - metabolism | Enzyme Inhibitors - chemical synthesis | Spectroscopy, Fourier Transform Infrared | Carbonic Anhydrase II - antagonists & inhibitors | Cholinergic Antagonists - pharmacology | Hydrazines - chemistry | Hydrazines - chemical synthesis | Butyrylcholinesterase - chemistry | Cobalt - pharmacology | Proton Magnetic Resonance Spectroscopy | Butyrylcholinesterase - metabolism | Magnetic Phenomena | Enzyme Inhibitors - chemistry | Carbon-13 Magnetic Resonance Spectroscopy | Coordination Complexes - pharmacology | Molecular Structure | Nickel - pharmacology | Glycoside Hydrolases - antagonists & inhibitors | Hydrazines - pharmacology | Nickel - chemistry | Enzyme Inhibitors - pharmacology | Hypoglycemic Agents - chemistry | Acetylcholinesterase - chemistry | Carbonic Anhydrase I - chemistry | Coordination Complexes - chemistry | Hypoglycemic Agents - pharmacology | Animals | Cholinesterase Inhibitors - pharmacology | Carbonic Anhydrase I - antagonists & inhibitors | Cholinergic Antagonists - chemistry | Hypoglycemic Agents - chemical synthesis | Glycoside Hydrolases - metabolism | Acetylcholinesterase - metabolism | Cobalt - chemistry | Infrared spectroscopy | Hydrazines | Water chemistry | Oxygen | Diabetes mellitus | Nitrogen atoms | Acetylcholinesterase | Magnetic susceptibility | Oxygen atoms | Carbonic anhydrase | Magnetic permeability | Isoforms | Acetylcholine receptors | Nickel | Thermal analysis | Hydrazine | Crystal structure | Metal ions | Index Medicus
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 04/2014, Volume 57, Issue 8, pp. 3205 - 3212
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 03/2015, Volume 93, pp. 564 - 573
A series of novel chalcone-triazole derivatives were synthesized and screened for in vitro anticancer activity on the human cancer cell lines IMR32... 
1,2,3-Triazoles | α-Glucosidase inhibition | Chromanochalcones | Molecular docking | Anticancer activity | CHEMISTRY, MEDICINAL | CLICK CHEMISTRY | ALPHA-GLUCOSIDASE | DRUG DISCOVERY | BIOLOGICAL EVALUATION | alpha-Glucosidase inhibition | HIV-1 PROTEASE | INHIBITORS | CANCER-RESEARCH | DERIVATIVES | ANTIMICROBIAL ACTIVITY | Triazoles - adverse effects | Chalcone - chemistry | Glycoside Hydrolase Inhibitors - adverse effects | Hypoglycemic Agents - metabolism | Antineoplastic Agents - chemical synthesis | Glycoside Hydrolase Inhibitors - metabolism | Humans | Structure-Activity Relationship | Antigens, Neoplasm - chemistry | Antineoplastic Agents - metabolism | DNA-Binding Proteins - metabolism | Tissue Distribution | Antineoplastic Agents - adverse effects | DNA Topoisomerases, Type II - chemistry | Antigens, Neoplasm - metabolism | Triazoles - chemical synthesis | Antineoplastic Agents - pharmacology | DNA Topoisomerases, Type II - metabolism | Chemistry Techniques, Synthetic | Rats | Glycoside Hydrolase Inhibitors - pharmacology | DNA-Binding Proteins - chemistry | Hypoglycemic Agents - pharmacology | Glycoside Hydrolase Inhibitors - chemical synthesis | Triazoles - pharmacology | Triazoles - metabolism | Animals | Hypoglycemic Agents - chemical synthesis | Cell Line, Tumor | Protein Conformation | Cell Proliferation - drug effects | Molecular Docking Simulation | Hypoglycemic Agents - adverse effects | alpha-Glucosidases - metabolism | Anthracyclines | Research | Diabetes | Triazoles | Oncology, Experimental | Cancer | Index Medicus
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 06/2006, Volume 49, Issue 12, pp. 3614 - 3627
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2005, Volume 48, Issue 15, pp. 5025 - 5037
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2007, Volume 50, Issue 10, pp. 2297 - 2300
Journal Article
Diabetes, ISSN 0012-1797, 05/2013, Volume 62, Issue 5, pp. 1453 - 1463
Glucagon, an essential regulator of glucose homeostasis, also modulates lipid metabolism and promotes weight loss, as reflected by the wasting observed in... 
PPAR-ALPHA | BODY-WEIGHT | METABOLISM | FIBROBLAST-GROWTH-FACTOR-21 | PHARMACOLOGY | INCREASES ENERGY-EXPENDITURE | ENDOCRINOLOGY & METABOLISM | DEGRADATION | MICE | INSULIN SENSITIVITY | FGF21 | Obesity - drug therapy | Humans | Peptides - pharmacokinetics | Fibroblast Growth Factors - genetics | Male | Fibroblast Growth Factors - secretion | Obesity - blood | Anti-Obesity Agents - therapeutic use | Glucagon - agonists | Fibroblast Growth Factors - metabolism | Anti-Obesity Agents - pharmacokinetics | Peptides - chemical synthesis | Hepatocytes - secretion | Hypoglycemic Agents - therapeutic use | Receptors, Glucagon - agonists | Receptors, Glucagon - genetics | Hypoglycemic Agents - pharmacokinetics | Peptides - physiology | Rats | Hypoglycemic Agents - pharmacology | Mice, Knockout | Cross-Over Studies | Anti-Obesity Agents - chemical synthesis | Mice | Anti-Obesity Agents - pharmacology | Hepatocytes - pathology | Diabetes Mellitus, Type 2 - metabolism | Hepatocytes - metabolism | Molecular Targeted Therapy | Mice, Mutant Strains | HEK293 Cells | Adult | Female | Hepatocytes - drug effects | Recombinant Proteins - metabolism | Double-Blind Method | Cells, Cultured | Insulin Resistance | Receptors, Glucagon - metabolism | Recombinant Proteins - agonists | Glucagon - pharmacology | Obesity - metabolism | Diabetes Mellitus, Type 2 - blood | Animals | Fibroblast Growth Factors - blood | Hypoglycemic Agents - chemical synthesis | Glucagon - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Peptides - therapeutic use | Physiological aspects | Fibroblast growth factors | Research | Glucagon | Analysis | Index Medicus | Abridged Index Medicus | Original Research
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 01/2011, Volume 54, Issue 1, pp. 153 - 165
Journal Article
Journal Article