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Journal Article
Lancet, The, ISSN 0140-6736, 2009, Volume 373, Issue 9681, pp. 2125 - 2135
Summary Background Rosiglitazone is an insulin sensitiser used in combination with metformin, a sulfonylurea, or both, for lowering blood glucose in people... 
Internal Medicine | CARDIAC OUTCOMES | METFORMIN | MEDICINE, GENERAL & INTERNAL | MONOTHERAPY | MYOCARDIAL-INFARCTION | SULFONYLUREAS | HEART-ASSOCIATION | RISK | COMPLICATIONS | BLOOD-GLUCOSE CONTROL | FAILURE | Glycated Hemoglobin A - analysis | Myocardial Infarction - mortality | Body Weight | Metformin - therapeutic use | Prospective Studies | Humans | Middle Aged | Fractures, Bone - epidemiology | Hospitalization - statistics & numerical data | Male | Drug Utilization | Thiazolidinediones - therapeutic use | Cholesterol, LDL - blood | Female | Stroke - mortality | Drug Therapy, Combination | Heart Failure - epidemiology | Hypoglycemic Agents - therapeutic use | Administration, Oral | Sulfonylurea Compounds - therapeutic use | Angina, Unstable - epidemiology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Sex Factors | Cholesterol, HDL - blood | Diuretics - therapeutic use | Diabetes Mellitus, Type 2 - drug therapy | Neoplasms - epidemiology | Type 2 diabetes | Patient outcomes | Dosage and administration | Drug therapy, Combination | Research | Metformin | Rosiglitazone maleate | Drug therapy | Health aspects | Heart failure | Studies | Clinical trials | Data collection | Blood pressure | Diabetes | Marketing | Index Medicus | Abridged Index Medicus | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
Journal Article
ANNALS OF INTERNAL MEDICINE, ISSN 0003-4819, 01/2011, Volume 154, Issue 2, pp. 103 - 103
Background: Insulin replacement in diabetes often requires prandial intervention to reach hemoglobin A(1c) (HbA(1c)) targets. Objective: To test whether... 
NPH INSULIN | MEDICINE, GENERAL & INTERNAL | GLYCEMIC CONTROL | ORAL-THERAPY | ADD-ON | GLUCOSE-LOWERING DRUGS | COMBINATION THERAPY | PARALLEL-GROUP | NAIVE PEOPLE | OPEN-LABEL | TO-TARGET TRIAL | Metformin - therapeutic use | Glycated Hemoglobin A - metabolism | Humans | Middle Aged | Body Weight - drug effects | Male | Thiazolidinediones - administration & dosage | Peptides - administration & dosage | Thiazolidinediones - therapeutic use | Hypoglycemic Agents - administration & dosage | Injections, Subcutaneous | Sensitivity and Specificity | Venoms - administration & dosage | Female | Insulin - analogs & derivatives | Metformin - administration & dosage | Drug Therapy, Combination | Hypoglycemic Agents - therapeutic use | Insulin, Long-Acting | Double-Blind Method | Drug Administration Schedule | Venoms - adverse effects | Insulin - administration & dosage | Diabetes Mellitus, Type 2 - blood | Insulin Glargine | Venoms - therapeutic use | Aged | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Insulin - therapeutic use | Peptides - adverse effects | Peptides - therapeutic use | Type 2 diabetes | Glycosylated hemoglobin | Physiological aspects | Research | Diagnosis | Drug therapy | Injections | Side effects | Clinical trials | Diabetes | Hypoglycemia | Insulin | Weight | Index Medicus | Abridged Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 10/2013, Volume 369, Issue 14, pp. 1317 - 1326
Saxagliptin, a new oral antihyperglycemic drug in the DPP-4 inhibitor class, had no effect on the risk of cardiovascular events in patients with type 2... 
ALL-CAUSE | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | EVENTS | GLUCOSE CONTROL | MICROALBUMINURIA | DISEASE | CLINICAL-USE | PREVENTION | RISK | DEATH | Dipeptidyl-Peptidase IV Inhibitors - adverse effects | Dipeptidyl-Peptidase IV Inhibitors - therapeutic use | Humans | Middle Aged | Hospitalization - statistics & numerical data | Male | Adamantane - therapeutic use | Aged, 80 and over | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Female | Hypoglycemia - chemically induced | Heart Failure - epidemiology | Diabetes Mellitus, Type 2 - complications | Adamantane - adverse effects | Adamantane - analogs & derivatives | Hypoglycemic Agents - therapeutic use | Cardiovascular Diseases - etiology | Dipeptides - therapeutic use | Double-Blind Method | Pancreatitis - epidemiology | Dipeptides - adverse effects | Kaplan-Meier Estimate | Pancreatitis - chemically induced | Aged | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Type 2 diabetes | Complications and side effects | Patient outcomes | Dosage and administration | Drug therapy | Heart diseases | Risk factors | Saxagliptin | Myocardial infarction | Cerebral infarction | Heart attacks | Peptidase | Diabetes mellitus | Pancreatitis | Cardiovascular disease | Angina | Patients | Heart rate | Ischemia | Diabetes | Cardiovascular diseases | Diabetes mellitus (non-insulin dependent) | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2012, Volume 122, Issue 4, pp. 1339 - 1353
Defective brain insulin signaling has been suggested to contribute to the cognitive deficits in patients with Alzheimer's disease (AD). Although a connection... 
MAMMALIAN TARGET | MEDICINE, RESEARCH & EXPERIMENTAL | INTRANASAL INSULIN | RECEPTOR-DEPENDENT MECHANISM | AMYLOID-BETA | AXONAL-TRANSPORT | TNF-ALPHA | SYNAPTIC PLASTICITY | CULTURED HIPPOCAMPAL-NEURONS | PEPTIDE OLIGOMERS | TRANSGENIC MICE | Phosphorylation | Insulin - physiology | Humans | Middle Aged | Macaca fascicularis | Memory Disorders - metabolism | Male | Hippocampus - drug effects | Insulin Receptor Substrate Proteins - metabolism | Infliximab | Alzheimer Disease - prevention & control | Aged, 80 and over | Female | Neurons - metabolism | Neurons - drug effects | Alzheimer Disease - psychology | Hypoglycemic Agents - therapeutic use | Cells, Cultured - drug effects | Amyloid beta-Peptides - toxicity | Antibodies, Monoclonal - pharmacology | Mice, Inbred C57BL | Insulin Resistance | Rats | Mice, Transgenic | Hippocampus - pathology | Hippocampus - cytology | Maze Learning - drug effects | Hypoglycemic Agents - pharmacology | Peptides - pharmacology | Hippocampus - metabolism | Memory Disorders - prevention & control | Animals | MAP Kinase Signaling System - drug effects | Memory Disorders - etiology | Alzheimer Disease - metabolism | Venoms - therapeutic use | Aged | Cells, Cultured - metabolism | Mice | Protein Processing, Post-Translational | Venoms - pharmacology | Alzheimer Disease - genetics | Peptides - therapeutic use | Index Medicus | Abridged Index Medicus
Journal Article
Diabetes Care, ISSN 0149-5992, 02/2012, Volume 35, Issue 2, pp. 252 - 258
Journal Article