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Annals of Oncology, ISSN 0923-7534, 5/2009, Volume 20, Issue 5, pp. 921 - 927
Background: Locally advanced laryngeal and hypopharyngeal cancers (LHC) represent a group of cancers for which surgery, laryngectomy-free survival (LFS),... 
Head and neck cancer | Chemotherapy | Hypopharynx cancer | Larynx cancer | Organ preservation | Chemoradiotherapy | larynx cancer | head and neck cancer | chemoradiotherapy | FLUOROURACIL | chemotherapy | ADVANCED HEAD | DOCETAXEL | hypopharynx cancer | NECK-CANCER | PHASE-III TRIAL | NEOADJUVANT CHEMOTHERAPY | CISPLATIN | ONCOLOGY | CONCURRENT CHEMOTHERAPY | RADIOTHERAPY | CARCINOMA | organ preservation | Laryngeal Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - surgery | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Male | Hypopharyngeal Neoplasms - mortality | Carcinoma, Squamous Cell - radiotherapy | Laryngectomy | Cisplatin - administration & dosage | Laryngeal Neoplasms - pathology | Laryngeal Neoplasms - therapy | Carcinoma, Squamous Cell - mortality | Fluorouracil - administration & dosage | Time Factors | Aged, 80 and over | Laryngeal Neoplasms - drug therapy | Adult | Female | Chemotherapy, Adjuvant | Radiotherapy, Adjuvant | Laryngeal Neoplasms - surgery | Risk Assessment | Docetaxel | Kaplan-Meier Estimate | Proportional Hazards Models | Carcinoma, Squamous Cell - therapy | Treatment Outcome | Hypopharyngeal Neoplasms - therapy | Disease-Free Survival | Hypopharyngeal Neoplasms - radiotherapy | Taxoids - administration & dosage | Carcinoma, Squamous Cell - drug therapy | Laryngeal Neoplasms - mortality | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Hypopharyngeal Neoplasms - pathology | Aged | Hypopharyngeal Neoplasms - drug therapy
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2013, Volume 87, Issue 5, pp. 1078 - 1085
Purpose To compare the temporal lymph node (LN) regression and regional control (RC) after primary chemoradiation therapy/radiation therapy in human... 
Radiology | Hematology, Oncology and Palliative Medicine | METASTASIS | ONCOLOGY | DISSECTION | OROPHARYNGEAL CANCER | LYMPH-NODES | SQUAMOUS-CELL CARCINOMA | CHEMORADIATION | CHEMORADIOTHERAPY | HUMAN-PAPILLOMAVIRUS | RADIOTHERAPY | ONCOLOGY GROUP | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Laryngeal Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - surgery | Multivariate Analysis | Head and Neck Neoplasms - virology | Lymph Nodes - pathology | Hypopharyngeal Neoplasms - virology | Humans | Middle Aged | Male | Oropharyngeal Neoplasms - pathology | Laryngeal Neoplasms - pathology | Lymph Nodes - radiation effects | Aged, 80 and over | Laryngeal Neoplasms - drug therapy | Adult | Female | Papillomavirus Infections - virology | Remission Induction - methods | Oropharyngeal Neoplasms - drug therapy | Laryngeal Neoplasms - surgery | Head and Neck Neoplasms - drug therapy | Organ Size | Oropharyngeal Neoplasms - radiotherapy | Treatment Outcome | Lymph Nodes - virology | Oropharyngeal Neoplasms - virology | Head and Neck Neoplasms - pathology | Head and Neck Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - radiotherapy | Oropharyngeal Neoplasms - surgery | Hypopharyngeal Neoplasms - pathology | Aged | Combined Modality Therapy - methods | Hypopharyngeal Neoplasms - drug therapy | Neoplasm Staging | Head and Neck Neoplasms - surgery | Cohort Studies | Laryngeal Neoplasms - virology | Neck Dissection | Sects | Care and treatment | Radiotherapy | Nuclear radiation | Papillomavirus infections | Cancer | HEAD | MULTIVARIATE ANALYSIS | NEOPLASMS | LYMPH NODES | POSITRON COMPUTED TOMOGRAPHY | CHARGES | RADIOLOGY AND NUCLEAR MEDICINE | NECK | LARYNX | HAZARDS
Journal Article
Cancer, ISSN 0008-543X, 06/2016, Volume 122, Issue 12, pp. 1853 - 1860
Journal Article
Oral Oncology, ISSN 1368-8375, 11/2018, Volume 86, pp. 165 - 170
•57 TORS procedures for pyriform sinus carcinoma have been included retrospectively.•Surgical complications were dominated by tumor-site hemorrhage, with 3... 
Head and neck cancer | Organ preservation | Pyriform sinus cancer | Robotic hypopharyngectomy | Hypopharyngeal squamous cell carcinoma | Transoral robotic surgery | LASER MICROSURGERY | MULTICENTER | MANAGEMENT | FEASIBILITY | SAFETY | HYPOPHARYNGEAL CANCER | ONCOLOGY | DENTISTRY, ORAL SURGERY & MEDICINE | SQUAMOUS-CELL CARCINOMA | EXPERIENCE | TORS | Age Factors | Follow-Up Studies | Humans | Middle Aged | Pharyngectomy - methods | Squamous Cell Carcinoma of Head and Neck - pathology | Pharyngectomy - adverse effects | Male | Squamous Cell Carcinoma of Head and Neck - mortality | Conservative Treatment - methods | Hypopharyngeal Neoplasms - mortality | Feasibility Studies | Patient Selection | Organ Sparing Treatments - methods | Aged, 80 and over | Organ Sparing Treatments - adverse effects | Adult | Chemoradiotherapy, Adjuvant - statistics & numerical data | Female | Retrospective Studies | Conservative Treatment - adverse effects | Enteral Nutrition - statistics & numerical data | Robotic Surgical Procedures - methods | France - epidemiology | Pyriform Sinus - surgery | Chemoradiotherapy, Adjuvant - methods | Hypopharyngeal Neoplasms - therapy | Pyriform Sinus - pathology | Disease-Free Survival | Hypopharyngeal Neoplasms - pathology | Aged | Squamous Cell Carcinoma of Head and Neck - therapy | Robotic Surgical Procedures - adverse effects | Robotic surgery | Squamous cell carcinoma | Life Sciences
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2012, Volume 82, Issue 5, pp. 1823 - 1830
Purpose The tumor volume has been established as a significant predictor of outcomes among patients with head-and-neck cancer undergoing radiotherapy alone.... 
Radiology | Hematology, Oncology and Palliative Medicine | Primary tumor volume | Head and neck cancer | TNM staging | Tumor recurrence | Chemoradiotherapy | Survival | HYPOPHARYNGEAL CANCER | ONCOLOGY | POSITIVE HEAD | CARCINOMA | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Oropharyngeal Neoplasms - therapy | Prognosis | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Oropharyngeal Neoplasms - diagnostic imaging | Oropharyngeal Neoplasms - mortality | Laryngeal Neoplasms - diagnostic imaging | Male | Carcinoma, Squamous Cell - diagnostic imaging | Oropharyngeal Neoplasms - pathology | Hypopharyngeal Neoplasms - mortality | Laryngeal Neoplasms - pathology | Laryngeal Neoplasms - therapy | Squamous Cell Carcinoma of Head and Neck | Carcinoma, Squamous Cell - mortality | Aged, 80 and over | Adult | Female | Chemoradiotherapy - methods | Head and Neck Neoplasms - diagnostic imaging | Head and Neck Neoplasms - therapy | Neoplasm Recurrence, Local | Carcinoma, Squamous Cell - therapy | Survival Rate | Treatment Outcome | Tumor Burden | Head and Neck Neoplasms - pathology | Hypopharyngeal Neoplasms - therapy | Radiography | Disease-Free Survival | Analysis of Variance | Laryngeal Neoplasms - mortality | Hypopharyngeal Neoplasms - pathology | Aged | Head and Neck Neoplasms - mortality | Neoplasm Staging | Hypopharyngeal Neoplasms - diagnostic imaging | Medical colleges | Care and treatment | Nuclear radiation | Patient outcomes | Oncology, Experimental | Research | Radiotherapy | Tumors | Cancer | HEAD | PATIENTS | NEOPLASMS | FAILURES | METASTASES | LARYNX | COMPUTERIZED TOMOGRAPHY | PLANNING | MULTIVARIATE ANALYSIS | RADIOLOGY AND NUCLEAR MEDICINE | NECK | RADIOTHERAPY | COMBINED THERAPY | HAZARDS
Journal Article
Anticancer Research, ISSN 0250-7005, 09/2018, Volume 38, Issue 9, pp. 5321 - 5330
Background/Aim: The purpose of this study is to investigate the prognostic significance of the pretreatment F-NLR score, which is based on fibrinogen (F) and... 
Pretreatment biomarker | Radiotherapy | Neutrophil-to-lymphocyte ratio | F-NLR score | Hypopharyngeal squamous cell carcinoma | SURGERY | HEAD | METAANALYSIS | TUMOR PROGRESSION | NECK-CANCER | hypopharyngeal squamous cell carcinoma | neutrophil-to-lymphocyte ratio | ONCOLOGY | GASTRIC-CANCER | PLATELETS | radiotherapy | PROGNOSTIC NUTRITIONAL INDEX | MONOCYTE RATIO | CONCURRENT CHEMORADIOTHERAPY | Carcinoma, Squamous Cell - blood | Multivariate Analysis | Predictive Value of Tests | Area Under Curve | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Male | Hypopharyngeal Neoplasms - mortality | Hypopharyngeal Neoplasms - blood | Squamous Cell Carcinoma of Head and Neck | Carcinoma, Squamous Cell - mortality | Head and Neck Neoplasms - blood | Time Factors | Lymphocytes | Aged, 80 and over | Female | Retrospective Studies | Reproducibility of Results | Risk Factors | Decision Support Techniques | Head and Neck Neoplasms - therapy | Kaplan-Meier Estimate | Neutrophils | Proportional Hazards Models | Carcinoma, Squamous Cell - therapy | Treatment Outcome | Disease Progression | Head and Neck Neoplasms - pathology | Biomarkers, Tumor - blood | Hypopharyngeal Neoplasms - therapy | Disease-Free Survival | Fibrinogen - analysis | Hypopharyngeal Neoplasms - pathology | Lymphocyte Count | ROC Curve | Aged | Head and Neck Neoplasms - mortality
Journal Article
Head & Neck, ISSN 1043-3074, 04/2018, Volume 40, Issue 4, pp. 770 - 777
Background The purpose of this research was to investigate the association between alcohol dehydrogenase 1B (ADH1B) and aldehyde dehydrogenase 2 (ALDH2)... 
hypopharyngeal cancers | alcohol dehydrogenase‐aldehyde dehydrogenase (ADH‐ALDH) polymorphism | head and neck cancers | prognosis | alcohol dehydrogenase-aldehyde dehydrogenase (ADH-ALDH) polymorphism | SURGERY | HEAD | DRINKING | RISK | SMOKING | ESOPHAGEAL | NECK-CANCER | LESIONS | OTORHINOLARYNGOLOGY | SQUAMOUS-CELL CARCINOMA | JAPANESE | Hypopharyngeal Neoplasms - surgery | Hypopharyngeal Neoplasms - genetics | Prognosis | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Carcinoma, Squamous Cell - surgery | Male | Hypopharyngeal Neoplasms - mortality | Carcinoma, Squamous Cell - mortality | Adult | Retrospective Studies | Risk Assessment | Japan | Kaplan-Meier Estimate | Proportional Hazards Models | Aldehyde Dehydrogenase - genetics | Alcohol Drinking - adverse effects | Disease-Free Survival | Hypopharyngeal Neoplasms - pathology | Alcohol Dehydrogenase - genetics | Alleles | Survival Analysis | Aged | Polymorphism, Single Nucleotide | Cohort Studies | Cancer patients | Care and treatment | Squamous cell carcinoma | Patient outcomes | Genetic aspects | Single nucleotide polymorphisms | Aldehydes | Statistical analysis | Dehydrogenases | Cell survival | Alcohol | Single-nucleotide polymorphism | Alcohol dehydrogenase | Multivariate analysis | Gene polymorphism | Aldehyde dehydrogenase | Risk factors
Journal Article
Head & Neck, ISSN 1043-3074, 08/2016, Volume 38, Issue 8, pp. 1164 - 1169
Journal Article
Radiotherapy and Oncology, ISSN 0167-8140, 01/2018, Volume 126, Issue 1, pp. 3 - 24
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 08/2017, Volume 98, Issue 5, pp. 1002 - 1011
To present the long-term and final report of a phase 3 trial designed to assess dose-response relationship for postoperative radiation therapy (PORT) and... 
SQUAMOUS-CELL-CARCINOMA | SURGERY | IRRADIATION | ONCOLOGY | PHASE-III | LOCALLY ADVANCED HEAD | TIME | RADIOTHERAPY | COMBINATION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | CHEMOTHERAPY | CLAVICLES | Laryngeal Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - surgery | Prospective Studies | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Oropharyngeal Neoplasms - mortality | Carcinoma, Squamous Cell - surgery | Male | Oropharyngeal Neoplasms - pathology | Radiotherapy - adverse effects | Hypopharyngeal Neoplasms - mortality | Carcinoma, Squamous Cell - radiotherapy | Laryngeal Neoplasms - pathology | Carcinoma, Squamous Cell - mortality | Postoperative Care | Time Factors | Aged, 80 and over | Adult | Female | Mouth Neoplasms - radiotherapy | Radiotherapy Dosage | Laryngeal Neoplasms - surgery | Kaplan-Meier Estimate | Margins of Excision | Oropharyngeal Neoplasms - radiotherapy | Survival Rate | Mouth Neoplasms - mortality | Head and Neck Neoplasms - pathology | Head and Neck Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - radiotherapy | Oropharyngeal Neoplasms - surgery | Analysis of Variance | Laryngeal Neoplasms - mortality | Hypopharyngeal Neoplasms - pathology | Mouth Neoplasms - surgery | Mouth Neoplasms - pathology | Aged | Head and Neck Neoplasms - mortality | Dose-Response Relationship, Radiation | Head and Neck Neoplasms - surgery | Cancer patients | Care and treatment | Squamous cell carcinoma | Oncology, Experimental | Radiation | Clinical trials | Head and neck cancer | Research | Radiotherapy | Cancer
Journal Article
Radiotherapy and Oncology, ISSN 0167-8140, 2017, Volume 123, Issue 1, pp. 63 - 70
Abstract Background and purpose The goal of this study was to improve target definition by deriving modality-specific margins for clinical target volumes (CTV)... 
Hematology, Oncology and Palliative Medicine | GTV | Pathology | Head and neck cancer | CTV | Imaging | Larynx/diagnostic imaging | Tomography, X-Ray Computed/methods | Imaging, Three-Dimensional/methods | Humans | Middle Aged | Magnetic Resonance Imaging/methods | Male | Laryngectomy | Hypopharyngeal Neoplasms/diagnostic imaging | Hypopharynx/diagnostic imaging | Preoperative Care/methods | Female | Fluorodeoxyglucose F18 | Aged | Radiopharmaceuticals | Positron-Emission Tomography/methods | Laryngeal Neoplasms/diagnostic imaging | HEAD | INVASION | ONCOLOGY | TUMOR DELINEATION | VOLUME | RADIOTHERAPY | Pathology Head and neck cancer | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | ACCURACY | Hypopharyngeal Neoplasms - surgery | Hypopharynx - diagnostic imaging | Imaging, Three-Dimensional - methods | Magnetic Resonance Imaging - methods | Tomography, X-Ray Computed - methods | Laryngeal Neoplasms - diagnostic imaging | Hypopharynx - surgery | Laryngeal Neoplasms - pathology | Larynx - surgery | Larynx - diagnostic imaging | Laryngeal Neoplasms - surgery | Hypopharynx - pathology | Positron-Emission Tomography - methods | Larynx - pathology | Hypopharyngeal Neoplasms - pathology | Hypopharyngeal Neoplasms - diagnostic imaging | Preoperative Care - methods | Pets | PET imaging | Magnetic resonance imaging | Throat cancer | CT imaging
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, p. e78718
Background: High-risk human papillomavirus (HPV) is an oncogenic virus that causes oropharyngeal cancers, and it has a favorable outcome after the treatment.... 
PRESERVATION | SURGERY | HEAD | MULTIDISCIPLINARY SCIENCES | POSTOPERATIVE RADIOTHERAPY | OROPHARYNGEAL CANCER | SQUAMOUS-CELL CARCINOMA | HUMAN-PAPILLOMAVIRUS | NECK | EXPRESSION | Follow-Up Studies | Hypopharyngeal Neoplasms - virology | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Carcinoma, Squamous Cell - virology | Humans | Middle Aged | Male | Hypopharyngeal Neoplasms - mortality | Papillomavirus Infections - therapy | Papillomavirus Infections - pathology | Carcinoma, Squamous Cell - mortality | Adult | Female | Papillomavirus Infections - virology | Risk Factors | Carcinoma, Squamous Cell - therapy | Survival Rate | Papillomavirus Infections - mortality | Hypopharyngeal Neoplasms - therapy | Alphapapillomavirus - metabolism | Disease-Free Survival | Hypopharyngeal Neoplasms - metabolism | Papillomavirus Infections - metabolism | Hypopharyngeal Neoplasms - pathology | Aged | Medical research | Care and treatment | Squamous cell carcinoma | Adjuvant treatment | Medicine, Experimental | Development and progression | Papillomavirus infections | Health aspects | Cancer | Radiation | Otolaryngology | Viruses | Infections | Metastasis | Hybridization | Cancer therapies | Risk factors | Human papillomavirus | Etiology | Sinus | Oropharyngeal cancer | Surgery | Cell cycle | Dissection | Lymphatic system | Medical instruments | Health risks | Radiation therapy | Patients | Survival | Pharynx | Medicine | Pathology | Medical prognosis | Biomarkers | Head & neck cancer | Smoking
Journal Article