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International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2016, Volume 96, Issue 5, pp. 967 - 975
Abstract Purpose To assess the impact of radiation treatment time (RTT) in head and neck cancers on overall survival (OS) in the era of chemoradiation.... 
Radiology | Hematology, Oncology and Palliative Medicine | ONCOLOGY | CONCURRENT CHEMOTHERAPY | LARYNGEAL-CANCER | THERAPY ONCOLOGY GROUP | SQUAMOUS-CELL CARCINOMA | RANDOMIZED-TRIAL | STANDARD FRACTIONATION | LOCALLY ADVANCED HEAD | 1ST REPORT | PROLONGATION | RADIOTHERAPY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Laryngeal Neoplasms - radiotherapy | Radiotherapy - mortality | Humans | Oropharyngeal Neoplasms - mortality | Chemoradiotherapy - mortality | Hypopharyngeal Neoplasms - mortality | Tongue Neoplasms - drug therapy | Time Factors | Laryngeal Neoplasms - drug therapy | Tongue Neoplasms - radiotherapy | Tongue Neoplasms - mortality | Chemoradiotherapy - methods | Oropharyngeal Neoplasms - drug therapy | Head and Neck Neoplasms - drug therapy | Kaplan-Meier Estimate | Oropharyngeal Neoplasms - radiotherapy | Chi-Square Distribution | Tonsillar Neoplasms - mortality | Head and Neck Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - radiotherapy | Analysis of Variance | Laryngeal Neoplasms - mortality | Tonsillar Neoplasms - radiotherapy | Survival Analysis | Tonsillar Neoplasms - drug therapy | Head and Neck Neoplasms - mortality | Hypopharyngeal Neoplasms - drug therapy | Care and treatment | Cancer patients | Radiotherapy | Patient outcomes | Radiation | Cancer | HEAD | PATIENTS | SURVIVAL TIME | NEOPLASMS | RADIOLOGY AND NUCLEAR MEDICINE | NECK | LYMPHATIC SYSTEM | CHEMOTHERAPY | Head and Neck Cancer | Treatment time | National Cancer Database | Squamous Cell
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2010, Volume 76, Issue 5, pp. 1360 - 1368
Purpose The aim of this study was to investigate prospectively the weekly volume changes in the target volumes and organs at risk and the resulting dosimetric... 
Radiology | Hematology, Oncology and Palliative Medicine | Head and neck cancer | Volume changes | Chemo-IMRT | Dosimetric changes | SYSTEM | DELINEATION | IMRT | ONCOLOGY | GUIDELINES | RADIOTHERAPY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Laryngeal Neoplasms - radiotherapy | Prospective Studies | Humans | Oropharyngeal Neoplasms - diagnostic imaging | Spinal Cord - radiation effects | Laryngeal Neoplasms - diagnostic imaging | Oropharyngeal Neoplasms - pathology | Cisplatin - administration & dosage | Laryngeal Neoplasms - pathology | Nasopharyngeal Neoplasms - pathology | Nasopharyngeal Neoplasms - radiotherapy | Fluorouracil - administration & dosage | Time Factors | Laryngeal Neoplasms - drug therapy | Nasopharyngeal Neoplasms - drug therapy | Brain Stem - radiation effects | Radiotherapy Dosage | Nasopharyngeal Neoplasms - diagnostic imaging | Oropharyngeal Neoplasms - drug therapy | Parotid Gland - diagnostic imaging | Head and Neck Neoplasms - diagnostic imaging | Radiotherapy, Intensity-Modulated - methods | Head and Neck Neoplasms - drug therapy | Oropharyngeal Neoplasms - radiotherapy | Tumor Burden | Head and Neck Neoplasms - pathology | Radiography | Head and Neck Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - radiotherapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Parotid Gland - radiation effects | Hypopharyngeal Neoplasms - pathology | Combined Modality Therapy - methods | Hypopharyngeal Neoplasms - drug therapy | Hypopharyngeal Neoplasms - diagnostic imaging | Care and treatment | Chemotherapy | Oncology, Experimental | Radiation | Research | Radiotherapy | Cancer | TOMOGRAPHY | HEAD | DIAGNOSTIC TECHNIQUES | NEOPLASMS | RADIATION DOSES | MEDICINE | COMPUTERIZED TOMOGRAPHY | CHEMOTHERAPY | NUCLEAR MEDICINE | CAT SCANNING | DISEASES | THERAPY | DOSES | RADIOLOGY AND NUCLEAR MEDICINE | NECK | BODY | COMBINED THERAPY | RADIOLOGY
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2013, Volume 87, Issue 5, pp. 1078 - 1085
Purpose To compare the temporal lymph node (LN) regression and regional control (RC) after primary chemoradiation therapy/radiation therapy in human... 
Radiology | Hematology, Oncology and Palliative Medicine | METASTASIS | ONCOLOGY | DISSECTION | OROPHARYNGEAL CANCER | LYMPH-NODES | SQUAMOUS-CELL CARCINOMA | CHEMORADIATION | CHEMORADIOTHERAPY | HUMAN-PAPILLOMAVIRUS | RADIOTHERAPY | ONCOLOGY GROUP | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Laryngeal Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - surgery | Multivariate Analysis | Head and Neck Neoplasms - virology | Lymph Nodes - pathology | Hypopharyngeal Neoplasms - virology | Humans | Middle Aged | Male | Oropharyngeal Neoplasms - pathology | Laryngeal Neoplasms - pathology | Lymph Nodes - radiation effects | Aged, 80 and over | Laryngeal Neoplasms - drug therapy | Adult | Female | Papillomavirus Infections - virology | Remission Induction - methods | Oropharyngeal Neoplasms - drug therapy | Laryngeal Neoplasms - surgery | Head and Neck Neoplasms - drug therapy | Organ Size | Oropharyngeal Neoplasms - radiotherapy | Treatment Outcome | Lymph Nodes - virology | Oropharyngeal Neoplasms - virology | Head and Neck Neoplasms - pathology | Head and Neck Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - radiotherapy | Oropharyngeal Neoplasms - surgery | Hypopharyngeal Neoplasms - pathology | Aged | Combined Modality Therapy - methods | Hypopharyngeal Neoplasms - drug therapy | Neoplasm Staging | Head and Neck Neoplasms - surgery | Cohort Studies | Laryngeal Neoplasms - virology | Neck Dissection | Sects | Care and treatment | Radiotherapy | Nuclear radiation | Papillomavirus infections | Cancer | HEAD | MULTIVARIATE ANALYSIS | NEOPLASMS | LYMPH NODES | POSITRON COMPUTED TOMOGRAPHY | CHARGES | RADIOLOGY AND NUCLEAR MEDICINE | NECK | LARYNX | HAZARDS
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2011, Volume 81, Issue 1, pp. 126 - 134
Purpose To perform a comprehensive cognitive function (CF) assessment in patients who were relapse free after curative intent radiotherapy (RT) or... 
Radiology | Hematology, Oncology and Palliative Medicine | Squamous cell carcinoma of the head and neck | Chemotherapy | Neuropsychological testing | Radiotherapy | Cognitive dysfunction | PROPHYLACTIC CRANIAL IRRADIATION | ADJUVANT CHEMOTHERAPY | DRIVING PERFORMANCE | FOLLOW-UP | CELL LUNG-CANCER | BREAST-CANCER | NASOPHARYNGEAL CARCINOMA | ONCOLOGY | NEUROCOGNITIVE FUNCTION | LOW-GRADE GLIOMA | QUALITY-OF-LIFE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Laryngeal Neoplasms - radiotherapy | Pharyngeal Neoplasms - radiotherapy | Cerebellum - radiation effects | Prospective Studies | Humans | Middle Aged | Male | Pharyngeal Neoplasms - drug therapy | Antineoplastic Agents - administration & dosage | Cognition - physiology | Laryngeal Neoplasms - drug therapy | Neoplasms, Squamous Cell - pathology | Carcinoma - drug therapy | Carcinoma - blood | Affect - physiology | Head and Neck Neoplasms - drug therapy | Cognition - drug effects | Neoplasms, Squamous Cell - blood | Head and Neck Neoplasms - pathology | Carcinoma, Squamous Cell | Neuropsychological Tests | Cognition Disorders - diagnosis | Memory Disorders - etiology | Hypopharyngeal Neoplasms - pathology | Quality of Life | Pharyngeal Neoplasms - pathology | Hypopharyngeal Neoplasms - drug therapy | Temporal Lobe - drug effects | Laryngeal Neoplasms - blood | Cerebellum - drug effects | Hypopharyngeal Neoplasms - blood | Cisplatin - administration & dosage | Feasibility Studies | Laryngeal Neoplasms - pathology | Squamous Cell Carcinoma of Head and Neck | Head and Neck Neoplasms - blood | Antineoplastic Agents - adverse effects | Cognition Disorders - etiology | Neoplasms, Squamous Cell - drug therapy | Neoplasms, Squamous Cell - radiotherapy | Female | Carcinoma - pathology | Cognition - radiation effects | Affect - drug effects | Pharyngeal Neoplasms - blood | Affect - radiation effects | Carcinoma - radiotherapy | Combined Modality Therapy - adverse effects | Head and Neck Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - radiotherapy | Cisplatin - adverse effects | Aged | Combined Modality Therapy - methods | Temporal Lobe - radiation effects | Care and treatment | Squamous cell carcinoma | Cancer | BODY FLUIDS | HEAD | NERVOUS SYSTEM | RADIATION DOSES | MEDICINE | THERAPY | CEREBELLUM | RADIOLOGY AND NUCLEAR MEDICINE | RADIOTHERAPY | COMBINED THERAPY | BRAIN | RADIOLOGY | BLOOD | NEOPLASMS | BIOLOGICAL MATERIALS | CENTRAL NERVOUS SYSTEM | STANDARD OF LIVING | CHEMOTHERAPY | NUCLEAR MEDICINE | ORGANS | DISEASES | DOSES | CARCINOMAS | NECK | DOSIMETRY | BODY | MATERIALS
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 03/2013, Volume 31, Issue 7, pp. 853 - 859
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2011, Volume 79, Issue 2, pp. 429 - 435
Purpose Volumetric modulated arc therapy (RapidArc, Varian Medical Systems) permits the delivery of highly conformal dose distributions. We studied planning... 
Radiology | Hematology, Oncology and Palliative Medicine | Head-and-neck cancer | Locally advanced disease | Volumetric modulated arc therapy | RapidArc | Dose distribution | DYSPHAGIA | IMRT | OROPHARYNGEAL CARCINOMA | VOLUME RESPONSE ANALYSIS | PAROTID-GLAND FUNCTION | MODULATED RADIATION-THERAPY | DELINEATION | ARC | IMPACT | ONCOLOGY | RADIOTHERAPY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Laryngeal Neoplasms - radiotherapy | Radiotherapy Dosage | Organs at Risk - radiation effects | Oropharyngeal Neoplasms - drug therapy | Radiotherapy Planning, Computer-Assisted - methods | Humans | Radiotherapy, Intensity-Modulated - methods | Head and Neck Neoplasms - drug therapy | Oropharyngeal Neoplasms - radiotherapy | Antineoplastic Agents - therapeutic use | Oropharyngeal Neoplasms - pathology | Tumor Burden | Head and Neck Neoplasms - pathology | Laryngeal Neoplasms - pathology | Head and Neck Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - pathology | Laryngeal Neoplasms - drug therapy | Combined Modality Therapy - methods | Hypopharyngeal Neoplasms - drug therapy | Phantoms, Imaging | Film Dosimetry | Care and treatment | Cancer patients | Cancer | HEAD | RADIATION DOSE DISTRIBUTIONS | DISEASES | THERAPY | NEOPLASMS | RADIOLOGY AND NUCLEAR MEDICINE | NECK | MEDICINE | BODY | COMBINED THERAPY | DELIVERY | PLANNING
Journal Article
Annals of Oncology, ISSN 0923-7534, 5/2009, Volume 20, Issue 5, pp. 921 - 927
Background: Locally advanced laryngeal and hypopharyngeal cancers (LHC) represent a group of cancers for which surgery, laryngectomy-free survival (LFS),... 
Head and neck cancer | Chemotherapy | Hypopharynx cancer | Larynx cancer | Organ preservation | Chemoradiotherapy | larynx cancer | head and neck cancer | chemoradiotherapy | FLUOROURACIL | chemotherapy | ADVANCED HEAD | RADIATION | DOCETAXEL | hypopharynx cancer | NECK-CANCER | PHASE-III TRIAL | NEOADJUVANT CHEMOTHERAPY | CISPLATIN | ONCOLOGY | CONCURRENT CHEMOTHERAPY | CARCINOMA | organ preservation | Laryngeal Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - surgery | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Male | Hypopharyngeal Neoplasms - mortality | Carcinoma, Squamous Cell - radiotherapy | Laryngectomy | Cisplatin - administration & dosage | Laryngeal Neoplasms - pathology | Laryngeal Neoplasms - therapy | Carcinoma, Squamous Cell - mortality | Fluorouracil - administration & dosage | Time Factors | Aged, 80 and over | Laryngeal Neoplasms - drug therapy | Adult | Female | Chemotherapy, Adjuvant | Radiotherapy, Adjuvant | Laryngeal Neoplasms - surgery | Risk Assessment | Kaplan-Meier Estimate | Proportional Hazards Models | Carcinoma, Squamous Cell - therapy | Treatment Outcome | Hypopharyngeal Neoplasms - therapy | Disease-Free Survival | Hypopharyngeal Neoplasms - radiotherapy | Taxoids - administration & dosage | Carcinoma, Squamous Cell - drug therapy | Laryngeal Neoplasms - mortality | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Hypopharyngeal Neoplasms - pathology | Aged | Hypopharyngeal Neoplasms - drug therapy
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2010, Volume 78, Issue 3, pp. 696 - 702
Purpose Erlotinib, an oral tyrosine kinase inhibitor, is active against head-and-neck squamous cell carcinoma (HNSCC) and possibly has a synergistic... 
Radiology | Hematology, Oncology and Palliative Medicine | Chemotherapy | Squamous cell carcinoma | Erlotinib | Radiotherapy | Epidermal growth factor receptor | PROSPECTIVE RANDOMIZED-TRIAL | PRIMARY LARYNGEAL-CANCER | CHEMORADIOTHERAPY | STAGE-III | RADIATION-THERAPY | GROWTH-FACTOR RECEPTOR | ONCOLOGY | CONCURRENT CHEMOTHERAPY | TGF-ALPHA | AERODIGESTIVE TRACT CANCER | EXPRESSION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Erlotinib Hydrochloride | Laryngeal Neoplasms - radiotherapy | Confidence Intervals | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Oropharyngeal Neoplasms - mortality | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Carcinoma, Squamous Cell - surgery | Male | Oropharyngeal Neoplasms - pathology | Hypopharyngeal Neoplasms - mortality | Carcinoma, Squamous Cell - radiotherapy | Cisplatin - administration & dosage | Laryngeal Neoplasms - pathology | Carcinoma, Squamous Cell - mortality | Brazil | Laryngeal Neoplasms - drug therapy | Adult | Female | Quinazolines - administration & dosage | Radiotherapy Dosage | Drug Eruptions - etiology | Oropharyngeal Neoplasms - drug therapy | Drug Administration Schedule | Head and Neck Neoplasms - drug therapy | Oropharyngeal Neoplasms - radiotherapy | Survival Rate | Combined Modality Therapy - adverse effects | Head and Neck Neoplasms - pathology | Head and Neck Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - radiotherapy | Carcinoma, Squamous Cell - drug therapy | Laryngeal Neoplasms - mortality | Hypopharyngeal Neoplasms - pathology | Quinazolines - adverse effects | Cisplatin - adverse effects | Aged | Combined Modality Therapy - methods | Head and Neck Neoplasms - mortality | Hypopharyngeal Neoplasms - drug therapy | Head and Neck Neoplasms - surgery | Salvage Therapy - methods | Tyrosine | Medical research | Care and treatment | Medicine, Experimental | Clinical trials | Cisplatin | Cancer | Index Medicus | HEAD | MITOGENS | RADIATION DOSES | MEDICINE | THERAPY | TYROSINE | AMINO ACIDS | DRUGS | RADIOLOGY AND NUCLEAR MEDICINE | RADIOTHERAPY | RADIOLOGY | MEMBRANE PROTEINS | NEOPLASMS | ORGANIC COMPOUNDS | HYDROXY ACIDS | ORGANIC ACIDS | TOXICITY | ANTINEOPLASTIC DRUGS | CHEMOTHERAPY | NUCLEAR MEDICINE | GROWTH FACTORS | DISEASES | DOSES | CARCINOMAS | CARBOXYLIC ACIDS | NECK | RECEPTORS | PROTEINS | BODY
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2010, Volume 78, Issue 5, pp. 1373 - 1380
Purpose To review outcome and toxicity of Stage IVa and IVb head-and-neck squamous cell carcinoma patients treated with concomitant chemotherapy and... 
Radiology | Hematology, Oncology and Palliative Medicine | Head-and-neck cancer | Altered fractionation | Chemotherapy | IMRT | Head-and neck cancer | ACCELERATED RADIOTHERAPY | TOXICITY | OROPHARYNGEAL CARCINOMA | CANCER | RADIATION-THERAPY | PRESERVATION | DELINEATION | ONCOLOGY | CONCURRENT CHEMOTHERAPY | CHEMORADIATION | LOCALLY ADVANCED HEAD | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Laryngeal Neoplasms - radiotherapy | Mouth Neoplasms - drug therapy | Radiotherapy Planning, Computer-Assisted - methods | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Oropharyngeal Neoplasms - mortality | Male | Antineoplastic Agents - therapeutic use | Oropharyngeal Neoplasms - pathology | Hypopharyngeal Neoplasms - mortality | Carcinoma, Squamous Cell - radiotherapy | Radiotherapy, Intensity-Modulated - adverse effects | Laryngeal Neoplasms - pathology | Carcinoma, Squamous Cell - mortality | Laryngeal Neoplasms - drug therapy | Adult | Dose Fractionation | Female | Mouth Neoplasms - radiotherapy | Retrospective Studies | Oropharyngeal Neoplasms - drug therapy | Radiotherapy, Intensity-Modulated - methods | Head and Neck Neoplasms - drug therapy | Oropharyngeal Neoplasms - radiotherapy | Treatment Outcome | Combined Modality Therapy - adverse effects | Mouth Neoplasms - mortality | Head and Neck Neoplasms - pathology | Radiography | Xerostomia - prevention & control | Head and Neck Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - radiotherapy | Carcinoma, Squamous Cell - drug therapy | Cisplatin - therapeutic use | Laryngeal Neoplasms - mortality | Hypopharyngeal Neoplasms - pathology | Organs at Risk - diagnostic imaging | Survival Analysis | Mouth Neoplasms - pathology | Aged | Combined Modality Therapy - methods | Head and Neck Neoplasms - mortality | Hypopharyngeal Neoplasms - drug therapy | Neoplasm Staging | Index Medicus | HEAD | NEOPLASMS | MEDICINE | IRRADIATION | FRACTIONATED IRRADIATION | DISEASES | THERAPY | CARCINOMAS | RADIOLOGY AND NUCLEAR MEDICINE | NECK | BODY | COMBINED THERAPY
Journal Article
Radiotherapy and Oncology, ISSN 0167-8140, 2013, Volume 110, Issue 1, pp. 16 - 24
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 4/2009, Volume 101, Issue 7, pp. 498 - 506
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 2016, Volume 108, Issue 4
Journal Article
Cancer Research, ISSN 0008-5472, 07/2011, Volume 71, Issue 13, pp. 4598 - 4607
RECQL1 and WRN proteins are RecQ DNA helicases that participate in suppression of DNA hyper-recombination and repair. In this study, we report evidence... 
CANCER-CELLS | REPAIR | CISPLATIN | ONCOLOGY | MITOTIC CATASTROPHE | DNA HELICASES | RESISTANCE | SENESCENCE | SYNDROME GENE | WERNER-SYNDROME PROTEIN | FAMILY HELICASES | RNA, Small Interfering - genetics | Hypopharyngeal Neoplasms - genetics | Hypopharyngeal Neoplasms - enzymology | Humans | Werner Syndrome Helicase | Exodeoxyribonucleases - antagonists & inhibitors | RecQ Helicases - genetics | Squamous Cell Carcinoma of Head and Neck | Cell Death - genetics | Carcinoma - enzymology | Neoplasms, Squamous Cell - drug therapy | Cell Death - drug effects | Exodeoxyribonucleases - genetics | Head and Neck Neoplasms - enzymology | Molecular Targeted Therapy - methods | Carcinoma - drug therapy | Neoplasms, Squamous Cell - enzymology | Gene Silencing | Head and Neck Neoplasms - drug therapy | Head and Neck Neoplasms - therapy | RecQ Helicases - biosynthesis | Combined Modality Therapy | Exodeoxyribonucleases - biosynthesis | Neoplasms, Squamous Cell - therapy | Cisplatin - pharmacology | Random Allocation | Carcinoma, Squamous Cell | Hypopharyngeal Neoplasms - therapy | Xenograft Model Antitumor Assays | Animals | Neoplasms, Squamous Cell - genetics | RecQ Helicases - antagonists & inhibitors | Cell Line, Tumor | Carcinoma - genetics | Carcinoma - therapy | Head and Neck Neoplasms - genetics | Mice | Mice, Inbred BALB C | HeLa Cells | Hypopharyngeal Neoplasms - drug therapy | RNA, Small Interfering - administration & dosage
Journal Article