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Endocrinology, ISSN 0013-7227, 05/2014, Volume 155, Issue 5, pp. 1887 - 1898
Traumatic brain injury is a leading cause of hypopituitarism, which compromises patients' recovery, quality of life, and life span. To date, there are no means... 
TRAUMATIC BRAIN-INJURY | CONTROLLED CORTICAL IMPACT | PROTEIN TRANSGENIC MICE | IN-VIVO | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | GROWTH-HORMONE-SECRETION | QUALITY-OF-LIFE | ARCUATE NUCLEUS | INFLAMMATORY RESPONSE | GHRH NEURONS | Neurons - pathology | Median Eminence - pathology | Ependymoglial Cells - metabolism | Male | Green Fluorescent Proteins - genetics | Brain Injuries - physiopathology | Recombinant Fusion Proteins - metabolism | Third Ventricle - pathology | Hypopituitarism - immunology | Hypopituitarism - pathology | Neurons - metabolism | Third Ventricle - metabolism | Ependymoglial Cells - pathology | Median Eminence - metabolism | Arcuate Nucleus of Hypothalamus - pathology | Disease Models, Animal | Biomarkers - metabolism | Hypothalamus - immunology | Tight Junctions - metabolism | Green Fluorescent Proteins - metabolism | Arcuate Nucleus of Hypothalamus - metabolism | Gene Expression Regulation | Neurons - immunology | Hypopituitarism - etiology | Mice, Transgenic | Hypothalamus - pathology | Permeability | Ependymoglial Cells - immunology | Growth Hormone-Releasing Hormone - genetics | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Growth Hormone-Releasing Hormone - metabolism | Animals | Hypothalamus - metabolism | Tight Junctions - immunology | Third Ventricle - immunology | Median Eminence - immunology | Arcuate Nucleus of Hypothalamus - immunology | Mice | Tight Junctions - pathology | Hypopituitarism - metabolism | Immunoglobulin G - metabolism
Journal Article
European Journal of Endocrinology, ISSN 0804-4643, 01/2008, Volume 158, Issue 1, pp. 3 - 9
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 04/2012, Volume 97, Issue 4, pp. E694 - E699
Journal Article
Stem Cell Reports, ISSN 2213-6711, 06/2016, Volume 6, Issue 6, pp. 858 - 872
Human pluripotent stem cells (hPSCs) provide an unlimited cell source for regenerative medicine. Hormone-producing cells are particularly suitable for cell... 
MOUSE ANTERIOR-PITUITARY | IN-VITRO | HYPOPITUITARISM | GENERATION | DIFFERENTIATION | SPECIFICATION | BMP SIGNALING CONTROLS | CULTURE | GLAND | TRANSPLANTATION | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Embryonic Stem Cells - cytology | Homeodomain Proteins - metabolism | Humans | Protein Tyrosine Phosphatases - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Transcription Factor AP-2 - metabolism | Protein Tyrosine Phosphatases - genetics | Dioxoles - pharmacology | Hypopituitarism - pathology | Cell Culture Techniques | Hypopituitarism - genetics | Corticotrophs - metabolism | GATA3 Transcription Factor - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Disease Models, Animal | Biomarkers - metabolism | Gene Expression | Fibroblast Growth Factors - pharmacology | Cell- and Tissue-Based Therapy | Adrenocorticotropic Hormone - biosynthesis | Adrenocorticotropic Hormone - secretion | Pluripotent Stem Cells - metabolism | Transcription Factor AP-2 - genetics | Thyrotrophs - cytology | Mice | Hypopituitarism - therapy | GATA3 Transcription Factor - genetics | Corticotrophs - drug effects | Embryonic Stem Cells - metabolism | Pituitary Gland - metabolism | Thyrotrophs - metabolism | Growth Hormone - biosynthesis | Benzamides - pharmacology | Growth Hormone - secretion | Nuclear Proteins - genetics | Pluripotent Stem Cells - cytology | Pituitary Gland - pathology | Corticotrophs - cytology | Nuclear Proteins - metabolism | Transcription Factors - genetics | Follicle Stimulating Hormone - biosynthesis | Bone Morphogenetic Protein 4 - pharmacology | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Animals | Follicle Stimulating Hormone - secretion | Embryonic Stem Cells - drug effects | Cell Differentiation - drug effects | Pluripotent Stem Cells - drug effects | Thyrotrophs - drug effects | Hypopituitarism - metabolism
Journal Article
Pituitary, ISSN 1386-341X, 8/2016, Volume 19, Issue 4, pp. 399 - 406
Journal Article
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, ISSN 1530-891X, 10/2018, Volume 24, Issue 10, pp. 875 - 881
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2009, Volume 4, Issue 3, p. e4815
Background: The adult endocrine pituitary is known to host several hormone-producing cells regulating major physiological processes during life. Some... 
BIOLOGY | Gene Expression | Cell Proliferation | Pituitary Gland - metabolism | Telomere - ultrastructure | Homeodomain Proteins - metabolism | Humans | Glial Cell Line-Derived Neurotrophic Factor Receptors - metabolism | Rats | Stem Cells - cytology | Transcription Factors - genetics | Stem Cells - metabolism | Glial Cell Line-Derived Neurotrophic Factor Receptors - genetics | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Stage-Specific Embryonic Antigens - metabolism | Animals | Bromodeoxyuridine - pharmacology | Octamer Transcription Factor-3 - metabolism | Pituitary Hormones - metabolism | Stem Cell Niche - metabolism | Mice | Pituitary Gland - cytology | Hypopituitarism - metabolism | Physiological aspects | Telomeres | Hormones | Intermediate filament proteins | Stem cells | Global Positioning System | Vimentin | Cell proliferation | Cell culture | Sox9 protein | Oct-4 protein | Genes | Homeostasis | Stem cell transplantation | Nervous system | Kinases | E-cadherin | Cyclin-dependent kinase 4 | Cyclin-dependent kinase | β-catenin | Allografts | Hypopituitarism | Neuroectoderm | Rodents | Cell cycle | Polarity | Pituitary gland | Physiology | Tumorigenesis | Telomerase | Elongation | Puberty | Cyclin-dependent kinases | Cell division | Abundance | Spheroids | Pregnancy | Medicine | Pathology | Lymphocytes B | Pituitary | Relative abundance | Biomarkers | Nuclei (cytology) | Tumors | Prophet of pit-1 protein
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, p. e0135502
The Nestin-Cre driver mouse line has mild hypopituitarism, reduced body weight, a metabolic phenotype and reduced anxiety. Although several causes have been... 
NERVOUS-SYSTEM | PROLACTIN RECEPTOR | DEFECTS | DISRUPTION | GENE | TRANSGENIC MOUSE | MEDIATED RECOMBINATION | MULTIDISCIPLINARY SCIENCES | RECEPTOR MESSENGER-RNA | BRAIN | Humans | Liver - metabolism | RNA, Messenger - genetics | Receptors, LDL - metabolism | Male | Mice, Transgenic | Nestin - metabolism | Growth Hormone-Releasing Hormone - metabolism | STAT5 Transcription Factor - metabolism | Animals | Human Growth Hormone - metabolism | Hypothalamus - metabolism | Integrases - metabolism | Mice | Insulin-Like Growth Factor I - metabolism | Somatotropin | Brain | Somatotropin releasing hormone | RNA | Low density lipoproteins | Liver | Body weight | Genetic aspects | Gene expression | Intermediate filament proteins | Neurosciences | Phosphorylation | Nestin | Growth rate | Transcription | Insulin-like growth factor I | Paracrine signalling | Fuel consumption | Nervous system | Insulin-like growth factors | Activation | Recombinase | Hypothalamus | Fatty liver | Hypopituitarism | Prolactin | Rodents | Pituitary gland | Physiology | Anxiety | Phenotypes | Stat5 protein | CD36 antigen | Metabolism | Insulin | Cre recombinase | Molecular chains | Steatosis | Brain research | Molecular modelling | Growth hormone-releasing hormone | Human growth hormone | Weight reduction | Receptor density | Growth hormones | Growth hormone | Laboratory animals | Endocrinology
Journal Article
Endocrinology, ISSN 0013-7227, 02/2016, Volume 157, Issue 2, pp. 705 - 721
Journal Article
Molecular Endocrinology, ISSN 0888-8809, 06/2012, Volume 26, Issue 6, pp. 1014 - 1027
The pituitary is a complex gland comprising different cell types each secreting specific hormones. The extensive network of signaling molecules and... 
ADENOHYPOPHYSIS FORMATION | DOMAIN | EMBRYONIC-DEVELOPMENT | HYPOPITUITARISM | BETA-GENE | MOUSE | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | LENS INDUCTION | ALPHA | DIFFERENTIATION | Thyrotropin, beta Subunit - genetics | Thyrotrophs - metabolism | Glycoprotein Hormones, alpha Subunit - genetics | Gonadotrophs - metabolism | Zebrafish - embryology | Pituitary Gland, Anterior - metabolism | Gene Knockdown Techniques | Thyrotrophs - physiology | Gene Expression Regulation, Developmental | Follicle Stimulating Hormone, beta Subunit - metabolism | HMGB Proteins - genetics | HMGB Proteins - physiology | Pituitary Gland, Anterior - embryology | HMGB Proteins - metabolism | Transcription, Genetic | GATA2 Transcription Factor - genetics | Morpholinos - genetics | Zebrafish Proteins - metabolism | Luteinizing Hormone, beta Subunit - metabolism | Gonadotrophs - physiology | Zebrafish - genetics | Zebrafish Proteins - physiology | Organogenesis | Glycoprotein Hormones, alpha Subunit - metabolism | Thyrotropin, beta Subunit - metabolism | Animals | Analysis of Variance | Luteinizing Hormone, beta Subunit - genetics | Mucolipidoses | Pituitary Gland, Anterior - cytology | Zebrafish - metabolism | GATA2 Transcription Factor - metabolism | Follicle Stimulating Hormone, beta Subunit - genetics | Zebrafish Proteins - genetics | Original Research
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 7, p. e11443
Nestin-Cre mice express Cre recombinase under control of the rat nestin promoter and central nervous system (CNS) enhancer. While endogenous Nestin is... 
RECOMBINATION | STEM-CELLS | ACTIVATION | HORMONE | GENE | MOUSE | GROWTH |