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PloS one, ISSN 1932-6203, 2012, Volume 7, Issue 10, p. e46923
Current evidence suggests that ghrelin, a stomach derived peptide, exerts its orexigenic action through specific modulation of Sirtuin1 (SIRT1)/p53 and... 
MAMMALIAN TARGET | HORMONE | BSX | MULTIDISCIPLINARY SCIENCES | GROWTH | INCREASES | RESISTANCE | AMPK | APPETITE | AGOUTI-RELATED PEPTIDE | NEUROPEPTIDE-Y | Ghrelin - administration & dosage | TOR Serine-Threonine Kinases - metabolism | Arcuate Nucleus of Hypothalamus - cytology | Male | Neuropeptide Y - metabolism | Appetite Stimulants - administration & dosage | Time Factors | Arcuate Nucleus of Hypothalamus - drug effects | Hypothalamus - drug effects | Appetite Stimulants - pharmacology | Hypothalamus - physiology | Arcuate Nucleus of Hypothalamus - metabolism | Rats | Ghrelin - pharmacology | Arcuate Nucleus of Hypothalamus - physiology | Agouti-Related Protein - metabolism | Rats, Sprague-Dawley | Feeding Behavior - physiology | Feeding Behavior - drug effects | Transcription Factors - metabolism | Eating - drug effects | Animals | Hypothalamus - metabolism | Hypothalamus - cytology | Signal Transduction - drug effects | Neuropeptide Y | Brain | RNA | DNA binding proteins | Tumor proteins | Protein kinases | Protein binding | TOR protein | Transcription factors | Peptides | p53 Protein | Arcuate nucleus | Neuropeptides | Thyroid gland | Hypothalamus | Kinases | AMP-activated protein kinase | Experiments | Proteins | Signal transduction | Pathways | Energy | FOXO1 protein | Metabolites | Ghrelin | Rodents | Modulation | Forkhead protein | Physiology | Chronic illnesses | Stomach | AMP | Rapamycin | Metabolism | Gene expression | Fatty acids | SIRT1 protein | Medicine | Signaling | Agouti-related protein | Metabolic pathways | Diabetes | Endocrinology
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2010, Volume 107, Issue 33, pp. 14875 - 14880
The neuronal circuits involved in the regulation of feeding behavior and energy expenditure are soft-wired, reflecting the relative activity of the... 
Obesity | Gliosis | Neurons | Neuroglia | Arcuate nucleus | Body weight | Rats | Melanocortins | Mice | Synapses | Brain | Inflammation | Vulnerability | High-fat diet | Synaptic plasticity | DEFENSE | MECHANISM | FOOD-INTAKE | GHRELIN | MULTIDISCIPLINARY SCIENCES | NPY/AGRP NEURONS | RATS | vulnerability | brain | ARCUATE NUCLEUS | BODY-WEIGHT | inflammation | high-fat diet | synaptic plasticity | LEPTIN RESISTANCE | FEEDING CIRCUITS | Immunohistochemistry | Synaptic Transmission - physiology | Melanocortins - metabolism | Male | Neuropeptide Y - metabolism | Neurons - ultrastructure | Synapses - metabolism | Female | Obesity - etiology | Neurons - metabolism | Arcuate Nucleus of Hypothalamus - pathology | Gliosis - etiology | Dietary Fats - adverse effects | Arcuate Nucleus of Hypothalamus - metabolism | Gliosis - metabolism | Mice, Inbred C57BL | Mice, Transgenic | Arcuate Nucleus of Hypothalamus - physiopathology | Hypothalamus - pathology | Microscopy, Electron | Hypothalamus - physiopathology | Rats, Sprague-Dawley | Obesity - metabolism | Pro-Opiomelanocortin - metabolism | Animals | Hypothalamus - metabolism | Diet | Neuroplasticity | Physiological aspects | Hypothalamus | Research | Properties | Neuropeptide Y | Brain architecture | Feeding behavior | Circuits | Blood vessels | Energy expenditure | Melanocortin | Data processing | Proopiomelanocortin | Neuronal-glial interactions | High fat diet | Diets | Blood-brain barrier | Dendrites | Cell body | Biological Sciences
Journal Article
Diabetes (New York, N.Y.), ISSN 0012-1797, 2012, Volume 62, Issue 3, pp. 801 - 810
Hypothalamic glucose sensing is involved in the control of feeding behavior and peripheral glucose homeostasis, and glial cells are suggested to play an... 
OCTADECANEUROPEPTIDE ODN | ENERGY-BALANCE | POMC NEURONS | CULTURED RAT ASTROCYTES | FOOD-INTAKE | IN-VIVO | ENDOCRINOLOGY & METABOLISM | DIAZEPAM-BINDING INHIBITOR | GLIAL-CELLS | ARCUATE NUCLEUS | NEUROPEPTIDE-Y | Hypothalamus - secretion | Nerve Tissue Proteins - secretion | Rats, Wistar | Injections, Intraventricular | Arcuate Nucleus of Hypothalamus - cytology | Male | Glucose - administration & dosage | Neuroglia - drug effects | Diazepam Binding Inhibitor - antagonists & inhibitors | Appetite Stimulants - administration & dosage | Arcuate Nucleus of Hypothalamus - secretion | Arcuate Nucleus of Hypothalamus - drug effects | Receptors, Melanocortin - metabolism | Appetite Depressants - administration & dosage | Synaptic Transmission - drug effects | Hypothalamus - drug effects | Neuropeptides - secretion | Appetite Stimulants - pharmacology | Nerve Tissue Proteins - antagonists & inhibitors | Peptide Fragments - metabolism | Receptors, Melanocortin - antagonists & inhibitors | Tissue Culture Techniques | Appetite Depressants - pharmacology | Arcuate Nucleus of Hypothalamus - metabolism | Nerve Tissue Proteins - agonists | Peptide Fragments - secretion | Appetite Regulation - drug effects | Rats | Neuropeptides - metabolism | Neuroglia - secretion | Diazepam Binding Inhibitor - secretion | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Diazepam Binding Inhibitor - agonists | Diazepam Binding Inhibitor - metabolism | Animals | Hypothalamus - metabolism | Hypothalamus - cytology | Peptide Fragments - antagonists & inhibitors | Glucose - metabolism | Feedback, Physiological - drug effects | Neuroglia - metabolism | Protein Processing, Post-Translational | Appetitive Behavior - drug effects | Neuropeptides - antagonists & inhibitors | Physiological aspects | Brain | Research | Blood sugar | Analysis | Ligands (Biochemistry) | Life Sciences | Biochemistry, Molecular Biology | Signal Transduction
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2017, Volume 95, Issue 1, pp. 123 - 137.e8
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2004, Volume 24, Issue 11, pp. 2797 - 2805
The arcuate nucleus of the hypothalamus (ARH) is a critical component of forebrain pathways that regulate a variety of neuroendocrine functions, including an... 
POMC | Obesity | Neuroendocrine | Leptin | NPY | Arcuate | Development | Axon | cFos | Projection | Hypothalamus | Feeding | arcuate | development | neuroendocrine | MEDIOBASAL HYPOTHALAMUS | CONTAINING NEURONS | FOOD-INTAKE | leptin | NEUROSCIENCES | NEUROPEPTIDE-Y | GOLD-THIOGLUCOSE | INDUCED SUPPRESSION | PARAVENTRICULAR NUCLEUS | MESSENGER-RNA | feeding | POSTNATAL-DEVELOPMENT | axon | projection | hypothalamus | obesity | Hypothalamus - growth & development | Proto-Oncogene Proteins c-fos - biosynthesis | Hypothalamic Area, Lateral - cytology | Arcuate Nucleus of Hypothalamus - cytology | Male | Neurons - cytology | Arcuate Nucleus of Hypothalamus - growth & development | Paraventricular Hypothalamic Nucleus - cytology | Arcuate Nucleus of Hypothalamus - drug effects | Female | Leptin - pharmacology | Neurons - metabolism | Hypothalamus - drug effects | Neurons - drug effects | Animals, Newborn | Dorsomedial Hypothalamic Nucleus - drug effects | Dorsomedial Hypothalamic Nucleus - cytology | Hypothalamic Area, Lateral - growth & development | Mice, Inbred C57BL | Neural Pathways - growth & development | Feeding Behavior - physiology | Gene Expression Regulation - drug effects | Paraventricular Hypothalamic Nucleus - drug effects | Animals | Hypothalamus - cytology | Neural Pathways - cytology | Pro-Opiomelanocortin - biosynthesis | Hypothalamic Area, Lateral - drug effects | Dorsomedial Hypothalamic Nucleus - growth & development | Mice | Appetite Regulation - physiology | Paraventricular Hypothalamic Nucleus - growth & development | Fluorescent Dyes | Aging - metabolism | Plasticity | Repair
Journal Article
Journal Article
Journal Article
Nature neuroscience, ISSN 1546-1726, 2010, Volume 13, Issue 6, pp. 767 - 775
Journal Article