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Neuron, ISSN 0896-6273, 2009, Volume 62, Issue 4, pp. 479 - 493
Understanding the physiopathology of affective disorders and their treatment relies on the availability of experimental models that accurately mimic aspects of... 
STEMCELL | HUMDISEASE | MOLNEURO | SEROTONIN-1A RECEPTOR FUNCTION | MESSENGER-RNA | BETA-ARRESTINS | PROTEIN-COUPLED RECEPTORS | ANTIDEPRESSANT TREATMENT | CELL-PROLIFERATION | ADULT MICE | MAJOR DEPRESSION | DENTATE GYRUS | HIPPOCAMPAL NEUROGENESIS | NEUROSCIENCES | Depression - pathology | Microtubule-Associated Proteins - metabolism | Radiation | Arrestins - genetics | GTP-Binding Protein alpha Subunit, Gi2 - metabolism | Male | Hippocampus - drug effects | Antidepressive Agents, Second-Generation - therapeutic use | RNA, Messenger - metabolism | Arrestins - metabolism | Hypothalamus - radiation effects | Corticosterone - toxicity | Depression - drug therapy | GTP-Binding Protein alpha Subunit, Gi2 - genetics | Anxiety - diet therapy | Depression - chemically induced | Reaction Time - drug effects | Exploratory Behavior - drug effects | Neurogenesis - radiation effects | Neurogenesis - drug effects | Bromodeoxyuridine - metabolism | Fluoxetine - therapeutic use | Hypothalamus - drug effects | Disease Models, Animal | Cell Survival - drug effects | Drug Administration Schedule | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Neuropeptides - metabolism | Hippocampus - pathology | Cell Survival - radiation effects | Anxiety - pathology | Feeding Behavior - drug effects | Mice, Knockout | Gene Expression Regulation - drug effects | Animals | Hypothalamus - metabolism | Analysis of Variance | beta-Arrestin 2 | beta-Arrestins | Hippocampus - radiation effects | Gene Expression Regulation - radiation effects | Anxiety - chemically induced | Cell Proliferation - drug effects | Mice | Arrestins - deficiency | Cell Proliferation - radiation effects | Neurosciences | Corticosterone | Neurons | Fluoxetine | Analysis | Depression, Mental | Models | Survival analysis | Genotype & phenotype | Brain research | Antidepressants | Anxieties | Rodents | Behavior | Feeds | Neurogenesis | Index Medicus
Journal Article
Diabetologia, ISSN 0012-186X, 11/1997, Volume 40, Issue 11, pp. 1269 - 1277
Neuropeptide Y in the hypothalamus is a potent physiological stimulator of feeding, and may contribute to the characteristic metabolic defects of obesity when... 
hypothalamo-pituitary adrenal axis | proinsulin | vagus nerve | glucose utilisation | Medicine & Public Health | Human Physiology | Intracerebroventricular | insulin | Metabolic Diseases | neuropeptide Y | Internal Medicine | NERVOUS-SYSTEM | ACID | INVOLVEMENT | ENERGY-BALANCE | CUSHINGS-SYNDROME | OBESITY | CORTICOTROPIN-RELEASING FACTOR | INSULIN-RESISTANCE | ENDOCRINOLOGY & METABOLISM | intracerebroventricular | BETA-CELL | ADIPOSE-TISSUE | Injections, Intraventricular | Body Weight - drug effects | Neuropeptide Y - administration & dosage | Muscle, Skeletal - metabolism | Chromatography, High Pressure Liquid | Insulin - blood | Corticotropin-Releasing Hormone - analysis | Adipose Tissue - metabolism | Time Factors | Radioimmunoassay | Female | Corticosterone - blood | Hypothalamus - drug effects | Adrenocorticotropic Hormone - blood | Pituitary-Adrenal System - physiology | Pituitary-Adrenal System - drug effects | Hypothalamus - physiology | Rats | Glucose - pharmacology | Rats, Sprague-Dawley | Vagotomy | Eating - drug effects | Vagus Nerve - physiology | Organ Size - drug effects | Animals | Pancreas - anatomy & histology | Glucose - metabolism | Neuropeptide Y | Corticotropin releasing hormone | Glucose metabolism | Corticosterone | Physiological aspects | ACTH | Insulin resistance | Universities and colleges | Glucose | Dextrose | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 05/2012, Volume 485, Issue 7396, pp. 62 - 68
Journal Article
Diabetes, ISSN 0012-1797, 04/2017, Volume 66, Issue 4, pp. 908 - 919
Cell proliferation and neuroinflammation in the adult hypothalamus may contribute to the pathogenesis of obesity. We tested whether the intertwining of these... 
ENERGY-BALANCE | DEPRESSIVE-LIKE BEHAVIOR | RESIDENT MICROGLIA | INSULIN-RESISTANCE | INDOLEAMINE 2,3-DIOXYGENASE | ENDOCRINOLOGY & METABOLISM | CELL-PROLIFERATION | SATURATED FAT | NF-KAPPA-B | INDUCED OBESITY | MELANOCORTIN SYSTEM | Adiposity - immunology | Interleukin-1beta - drug effects | Cytarabine - pharmacology | Weight Gain - immunology | Obesity - immunology | NF-kappa B - immunology | Body Weight - drug effects | Cytidine - pharmacology | Male | Body Weight - immunology | Microglia - immunology | Arcuate Nucleus of Hypothalamus - drug effects | Diet, High-Fat | Tumor Necrosis Factor-alpha - immunology | Weight Gain - drug effects | Leptin - immunology | Hypothalamus - drug effects | Macrophages, Peritoneal - drug effects | Eating - immunology | Hypothalamus - immunology | Adiposity - drug effects | Microglia - drug effects | Interleukin-1beta - immunology | Macrophages, Peritoneal - immunology | Arabinonucleosides - pharmacology | Inflammation | Eating - drug effects | Animals | Tumor Necrosis Factor-alpha - drug effects | Antimitotic Agents - pharmacology | Arcuate Nucleus of Hypothalamus - immunology | Cell Proliferation - drug effects | Mice | NF-kappa B - drug effects | Insulin resistance | Research | Brain | Obesity | Diet | Cytokines | Rodents | Index Medicus | Abridged Index Medicus | Life Sciences
Journal Article
Cell Metabolism, ISSN 1550-4131, 05/2016, Volume 23, Issue 5, pp. 797 - 810
Journal Article
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 507, Issue 7491, pp. 238 - 242
Hunger is a hard-wired motivational state essential for survival. Agouti-related peptide (AgRP)-expressing neurons in the arcuate nucleus (ARC) at the base of... 
POMC NEURONS | LEPTIN | ENERGY-EXPENDITURE | PROTEIN | FOOD-INTAKE | NPY | MULTIDISCIPLINARY SCIENCES | FEEDING-BEHAVIOR | RECEPTORS | CELL-TYPES | HYPOTHALAMUS | Dependovirus - genetics | Paraventricular Hypothalamic Nucleus - physiology | Neural Pathways - drug effects | Neuronal Plasticity - drug effects | Arcuate Nucleus of Hypothalamus - cytology | Male | Neural Pathways - physiology | Cell Tracking | Eating - physiology | Satiety Response - physiology | Hunger - drug effects | Paraventricular Hypothalamic Nucleus - cytology | Clozapine - pharmacology | Thyrotropin-Releasing Hormone - metabolism | Neuronal Plasticity - physiology | Female | Food Deprivation | Integrases - metabolism | Agouti-Related Protein - deficiency | Appetite - physiology | Neurons - metabolism | Neurons - drug effects | Neurons, Afferent - drug effects | Peptide Fragments - metabolism | Arcuate Nucleus of Hypothalamus - metabolism | Appetite - drug effects | Clozapine - analogs & derivatives | Agouti-Related Protein - metabolism | Eating - drug effects | Rabies virus - genetics | Animals | Pituitary Adenylate Cyclase-Activating Polypeptide - metabolism | Brain Mapping | Mice | Neurons, Afferent - metabolism | Peptide Fragments - deficiency | Hunger - physiology | Physiological aspects | Electrophysiology | Neuropeptides | Physiological research | Hunger | Research | Studies | Brain | Neurons | Experiments | Light | Food | Index Medicus
Journal Article
Journal of Experimental Biology, ISSN 0022-0949, 06/2016, Volume 219, Issue 11, pp. 1659 - 1674
Fluctuations in oxygen (O-2) concentrations represent a major challenge to aerobic organisms and can be extremely damaging to their mitochondria. Marine... 
Hypoxia | Mitochondria | Phosphorylation | Proton leak | Substrate oxidation | Metabolic control analysis | POTATO-TUBER MITOCHONDRIA | OXIDATIVE-PHOSPHORYLATION | CADMIUM EXPOSURE | WHITE SEA LITTORINA | METABOLIC DEPRESSION | DOWN ELASTICITY ANALYSIS | BIOLOGY | OYSTERS CRASSOSTREA-VIRGINICA | ANAEROBIC METABOLISM | FRESH-WATER EXPOSURE | Aconitate Hydratase - metabolism | Protons | Oxygen - pharmacology | Pectinidae - drug effects | Aquatic Organisms - physiology | Membrane Potential, Mitochondrial - drug effects | RNA, Messenger - metabolism | Rest - physiology | Aquatic Organisms - drug effects | Hepatopancreas - physiopathology | Oxidation-Reduction - drug effects | Aconitate Hydratase - genetics | Stress, Physiological - drug effects | Homeostasis - drug effects | Phosphorylation - drug effects | Biomarkers - metabolism | Protease La - genetics | Hepatopancreas - drug effects | Anaerobiosis - drug effects | Pectinidae - physiology | RNA, Messenger - genetics | Mitochondria - metabolism | Mitochondria - drug effects | Aerobiosis - drug effects | Adenosine Diphosphate - pharmacology | Sodium-Potassium-Exchanging ATPase - metabolism | Animals | Hypoxia - physiopathology | Kinetics | Mercenaria - drug effects | Oxidative Stress - drug effects | Proteasome Endopeptidase Complex - metabolism | Mercenaria - physiology | Protease La - metabolism | Energy Metabolism - drug effects | Analysis | Rainbow trout | Physiological aspects | Hypothalamus | Research | Behavior | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 2016, Volume 537, Issue 7618, pp. 97 - 101
Journal Article