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Forensic Science International, ISSN 0379-0738, 2012, Volume 226, Issue 1, pp. 54 - 61
Abstract The aim of this study was to investigate the usefulness of postmortem biochemical investigations in the diagnosis of fatal hypothermia. 10 cases of... 
Pathology | Ketone bodies | Postmortem biochemistry | Blood | Hypothermia | Biochemical markers | C-REACTIVE PROTEIN | MEDICINE, LEGAL | FATTY DEGENERATION | ACCIDENTAL HYPOTHERMIA | MEDICOLEGAL AUTOPSY | CREATINE-KINASE MB | CORTICOTROPIN-RELEASING FACTOR | POSTMORTEM CHEMISTRY UPDATE | PERICARDIAL FLUID | CARDIAC TROPONIN-I | ACUTE COLD STRESS | Calcium - metabolism | Humans | Middle Aged | Hydrocortisone - metabolism | Male | Pericardium - metabolism | Case-Control Studies | Young Adult | Fatty Acids, Nonesterified - metabolism | 2-Propanol - metabolism | C-Reactive Protein - metabolism | Human Growth Hormone - metabolism | Vitreous Body - metabolism | Hypothermia - metabolism | Hypothermia - mortality | Adult | Female | Forensic Pathology | Hypothermia - diagnosis | Calcitonin - metabolism | Adrenocorticotropic Hormone - metabolism | Biomarkers - metabolism | Calcitonin Gene-Related Peptide | Acetone - metabolism | Magnesium - metabolism | Thyrotropin - metabolism | Protein Precursors - metabolism | Glucose - metabolism | Aged | Hydroxybutyrates - metabolism | Ketones - metabolism | Postmortem Changes | Epinephrine - metabolism | Diagnosis | Biological markers | Analysis | Legal medicine | Fluid | Histology | Forensic pathology | Glucose | Nitrogen | Studies | Rodents | Pituitary gland | Fatalities | Growth hormones | Females | Age
Journal Article
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology, ISSN 0363-6119, 04/2008, Volume 294, Issue 4, pp. 1185 - 1196
Two recent, large whole-genome association studies (GWAS) in European populations have associated a ∼47-kb region that contains part of the FTO gene with high... 
Obesity | Adipose tissue | Hypothalamus | CUTL1 | CCAAT DISPLACEMENT PROTEIN | DNA-BINDING | PHYSIOLOGY | DROSOPHILA-MELANOGASTER | CUT REPEATS | adipose tissue | FUSED-TOES FT | ADULT OBESITY | BARDET-BIEDL-SYNDROME | TRANSCRIPTION FACTOR | WING MARGIN | obesity | hypothalamus | GENOME-WIDE ASSOCIATION | Bardet-Biedl Syndrome - metabolism | Homeodomain Proteins - metabolism | Humans | Alpha-Ketoglutarate-Dependent Dioxygenase FTO | Male | RNA, Messenger - metabolism | Obesity - genetics | Embryo, Mammalian - metabolism | Mixed Function Oxygenases | Adipose Tissue - metabolism | Transfection | Gene Expression Regulation, Developmental | Oxo-Acid-Lyases - genetics | Bardet-Biedl Syndrome - genetics | Fasting - metabolism | Oxo-Acid-Lyases - metabolism | Energy Metabolism - genetics | Nuclear Proteins - genetics | Repressor Proteins - metabolism | Disease Models, Animal | Eating | Mice, Inbred C57BL | Stromal Cells - metabolism | Cells, Cultured | Gene Expression Regulation | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Leptin - genetics | Adiposity - genetics | Homeodomain Proteins - genetics | Obesity - metabolism | Proteins - genetics | Animals | Hypothalamus - metabolism | Proteins - metabolism | Adipocytes - metabolism | Adaptor Proteins, Signal Transducing - genetics | Hypothermia, Induced | Mice, Obese | Mice | Polymorphism, Single Nucleotide | Adaptor Proteins, Signal Transducing - metabolism
Journal Article
International Journal of Legal Medicine, ISSN 0937-9827, 3/2013, Volume 127, Issue 2, pp. 267 - 276
Journal Article
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN 0363-6119, 01/2016, Volume 310, Issue 1, pp. R41 - R54
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 12/2007, Volume 27, Issue 50, pp. 13635 - 13648
Hyperphosphorylated tau is the major component of paired helical filaments in neurofibrillary tangles found in Alzheimer's disease ( AD) brains, and tau... 
Insulin deficiency | Tau hyperphosphorylation | Diabetes mellitus | JNK | GSK-3 | PP2A | MAPK | CaMKII | Cdk5 | Kinase | β-amyloid precursor protein | Serine/threonine protein phosphatase | Alzheimer's disease | Streptozotocin | Hypothermia | diabetes mellitus | ABNORMALLY PHOSPHORYLATED-TAU | PROTEIN PHOSPHATASE 2A | DIABETES-MELLITUS | serine/threonine protein phosphatase | GROWTH-FACTOR-I | SPORADIC ALZHEIMER-DISEASE | cdk5 | insulin deficiency | AMYLOID PRECURSOR PROTEIN | BLOOD-BRAIN-BARRIER | NEUROSCIENCES | GLYCOGEN-SYNTHASE KINASE-3-BETA | tau hyperphosphorylation | kinase | streptozotocin | hypothermia | RECEPTOR SIGNAL-TRANSDUCTION | PAIRED HELICAL FILAMENTS | beta-amyloid precursor protein | Epitopes - metabolism | Body Temperature - drug effects | Hippocampus - chemistry | tau Proteins - metabolism | Male | Hypothermia - chemically induced | tau Proteins - chemistry | Dose-Response Relationship, Drug | Neocortex - metabolism | Microtubules - metabolism | Time Factors | Hypothermia - metabolism | Protein Binding - drug effects | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | Female | Microtubules - chemistry | Diabetes Mellitus, Experimental - chemically induced | Phosphorylation - drug effects | Diabetes Mellitus, Experimental - metabolism | Disease Models, Animal | Insulin - pharmacology | Protein Phosphatase 2 - antagonists & inhibitors | Mice, Inbred C57BL | Neocortex - chemistry | Solubility | Axons - metabolism | Enzyme Activation - drug effects | Hippocampus - metabolism | Insulin - metabolism | Neuropil - metabolism | Animals | Epitopes - drug effects | Protein Phosphatase 2 - metabolism | Mice | Streptozocin - toxicity | serine | threonine protein phosphatase
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2004, Volume 24, Issue 10, pp. 2401 - 2411
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, p. e57380
Background: Autism spectrum disorders (ASDs) are caused by both genetic and environmental factors. Mitochondria act to connect genes and environment by... 
RESPONSES | ACTIVATION | SURAMIN | PROTEIN | NEUROTRANSMISSION | MULTIDISCIPLINARY SCIENCES | IN-VIVO | RECEPTOR | STRESS | BRAIN | CHILDREN | Autistic Disorder - chemically induced | Electron Transport | Autistic Disorder - metabolism | Immunoglobulins - immunology | Autistic Disorder - immunology | Male | Fragile X Mental Retardation Protein - metabolism | Synaptosomes - metabolism | Suramin - administration & dosage | Behavior, Animal | Brain - metabolism | Hypothermia - metabolism | Social Behavior | Immunoglobulins - blood | Female | Poly I-C - adverse effects | Corticosterone - blood | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | Disease Models, Animal | Psychomotor Performance | Receptors, Nicotinic - metabolism | Purkinje Cells - metabolism | Signal Transduction | Mitochondria - metabolism | Synaptosomes - ultrastructure | Animals | Energy Metabolism | Hypothermia - drug therapy | Mitogen-Activated Protein Kinase 3 - metabolism | Mice | Autistic Disorder - drug therapy | Mitogen-Activated Protein Kinase 1 - metabolism | Autism | Cellular signal transduction | Metabolites | Analysis | Genes | Cerebellum | Suramin | Therapy | Pediatrics | Neurosciences | Pathogenesis | Disorders | Metabolic networks | Drug development | Kinases | Proteins | Signal transduction | Mitochondria | Rodents | Sensorimotor system | Immune response | Abnormalities | Extracellular signal-regulated kinase | Hazards | Environmental factors | Permeability | Medicine | Signaling | Polychlorinated biphenyls--PCB | Transduction | Psychiatry | Metabolic disorders | Ca2+/calmodulin-dependent protein kinase II | Hypothermia | PCB | Polychlorinated biphenyls
Journal Article
Nature, ISSN 0028-0836, 04/2016, Volume 532, Issue 7597, pp. 112 - 116
Journal Article
Chest, ISSN 0012-3692, 10/2007, Volume 132, Issue 4, pp. 1368 - 1378
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2017, Volume 12, Issue 3, p. e0174596
Mild hypothermia improves survival and neurological recovery after cardiac arrest (CA) and cardiopulmonary resuscitation (CPR). However, the mechanism... 
SURVIVAL | PATHOGENESIS | MULTIDISCIPLINARY SCIENCES | RATS | INJURY | GLOBAL CEREBRAL-ISCHEMIA | HOSPITAL CARDIAC-ARREST | VASCULAR-PERMEABILITY | EXPRESSION | NEUROPROTECTION | NEUROLOGICAL FUNCTION | Cardiopulmonary Resuscitation - methods | Cadherins - metabolism | Claudin-5 - metabolism | Heart Arrest - metabolism | Male | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Antigens, CD - genetics | Adherens Junctions - metabolism | Occludin - metabolism | Antigens, CD - metabolism | Brain - metabolism | Brain Edema - genetics | Occludin - genetics | Brain - blood supply | Matrix Metalloproteinase 9 - metabolism | Matrix Metalloproteinase 9 - genetics | Swine | Hypothermia, Induced - methods | Brain - ultrastructure | Zonula Occludens-1 Protein - metabolism | Cadherins - genetics | Disease Models, Animal | Tight Junctions - metabolism | Zonula Occludens-1 Protein - genetics | Microscopy, Electron, Transmission | Gene Expression | Brain Edema - metabolism | Ribonuclease, Pancreatic - genetics | Heart Arrest - genetics | Claudin-5 - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Blood-Brain Barrier - metabolism | Tight Junctions - ultrastructure | Animals | Ribonuclease, Pancreatic - metabolism | Adherens Junctions - ultrastructure | Heart Arrest - therapy | Care and treatment | Usage | Cardiac arrest | Physiological aspects | CPR (First aid) | Genetic aspects | Research | Vascular endothelial growth factor | Hypothermia | Membrane permeability | Emergency medical care | Matrix metalloproteinase | Angiogenin | Cardiopulmonary resuscitation--CPR | Ventricular fibrillation | Fibrillation | Blood-brain barrier | Moisture content | Temperature effects | Rodents | Water content | Breakdown | Attenuation | Metalloproteinase | Heart diseases | Resuscitation | Edema | Tight junctions | Cortex | Adherens junctions | Permeability | Gene expression | Cadherin | Survival | Catheters | Zonula occludens-1 protein | Gelatinase B | Livestock | Disruption | Ventricle | CPR | Cardiopulmonary resuscitation
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 02/2008, Volume 35, Issue 2, pp. 223 - 228
SUMMARY • Hydrogen sulphide (H2S) acts as a gaseous cellular messenger and has recently been reported to induce a suspended animation-like state in mice. The... 
rats | stress gastric ulcer | hydrogen sulphide | induced hypothermia | endoplasmic reticulum stress | Hydrogen sulphide | Rats | Stress gastric ulcer | Induced hypothermia | Endoplasmic reticulum stress | APOPTOSIS | PHYSIOLOGY | ASSAY | LIPID-PEROXIDATION | H2S | INJURY | ENDOPLASMIC-RETICULUM STRESS | ANIMATION-LIKE STATE | LIVER | PHARMACOLOGY & PHARMACY | PITUITARY-ADRENAL AXIS | BRAIN | Molecular Chaperones - metabolism | Body Temperature - drug effects | Endoplasmic Reticulum - metabolism | Stomach Ulcer - pathology | Gastric Mucosa - pathology | Male | Gastric Mucosa - metabolism | Stomach Ulcer - etiology | Endoplasmic Reticulum - drug effects | Hypothermia, Induced - methods | Stress, Psychological - metabolism | Gastric Mucosa - drug effects | Lipid Peroxidation - drug effects | Corticosterone - blood | Adrenocorticotropic Hormone - blood | Stomach Ulcer - prevention & control | Disease Models, Animal | Malondialdehyde - metabolism | Hydrogen Sulfide - pharmacology | Stomach Ulcer - metabolism | Heat-Shock Proteins - metabolism | Caspase 12 - metabolism | Rats, Sprague-Dawley | Stress, Psychological - pathology | Hydrogen Sulfide - therapeutic use | Animals | Oxygen Consumption - drug effects | Stress, Psychological - complications | Peroxidase - metabolism | Hypothermia, Induced, methods | Stress, Psychological, metabolism | Molecular Chaperones, metabolism | Hydrogen Sulfide, pharmacology | Endoplasmic Reticulum, drug effects | Heat-Shock Proteins, metabolism | Oxygen Consumption, drug effects | Caspase 12, metabolism | Stomach Ulcer, metabolism | Corticosterone, blood | Gastric Mucosa, pathology | Hydrogen Sulfide, therapeutic use | Lipid Peroxidation, drug effects | Gastric Mucosa, drug effects | Stress, Psychological, complications | Body Temperature, drug effects | Endoplasmic Reticulum, metabolism | Adrenocorticotropic Hormone, blood | Stomach Ulcer, etiology | Peroxidase, metabolism | Stress, Psychological, pathology | Malondialdehyde, metabolism | Gastric Mucosa, metabolism | Stomach Ulcer, prevention and control | Stomach Ulcer, pathology | Hypothermia
Journal Article