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1. Full Text Targeting metabolic transformation for cancer therapy
by Tennant, Daniel A and Durán, Raúl V and Gottlieb, Eyal
Nature reviews. Cancer, ISSN 1474-175X, 04/2010, Volume 10, Issue 4, pp. 267 - 277
Life Sciences & Biomedicine | Oncology | Science & Technology | Neoplasms - metabolism | Cell Hypoxia - drug effects | DNA Replication - drug effects | Humans | Survivors | DNA, Neoplasm - drug effects | Glycolysis - drug effects | Cell Division - drug effects | Drug Delivery Systems | Neoplasms - drug therapy | Neoplasms - genetics | Sensitivity and Specificity | Drug Design | Neoplasms - pathology | Care and treatment | Cancer cells | Physiological aspects | Cell metabolism | Research | Health aspects | Methods | Cancer | Index Medicus
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2. Full Text Clinical development of new drug-radiotherapy combinations
by Sharma, Ricky A and Plummer, Ruth and Stock, Julie K and Greenhalgh, Tessa A and Ataman, Ozlem and Kelly, Stephen and Clay, Robert and Adams, Richard A and Baird, Richard D and Billingham, Lucinda and Brown, Sarah R and Buckland, Sean and Bulbeck, Helen and Chalmers, Anthony J and Clack, Glen and Cranston, Aaron N and Damstrup, Lars and Ferraldeschi, Roberta and Forster, Martin D and Golec, Julian and Hagan, Russell M and Hall, Emma and Hanauske, Axel-R and Harrington, Kevin J and Haswell, Tom and Hawkins, Maria A and Illidge, Tim and Jones, Hazel and Kennedy, Andrew S and Mcdonald, Fiona and Melcher, Thorsten and O'Connor, James P. B and Pollard, John R and Saunders, Mark P and Sebag-Montefiore, David and Smitt, Melanie and Staffurth, John and Stratford, Ian J and Wedge, Stephen R and NCRI CTRad Acad-Pharma Joint Worki and NCRI CTRad Academia-Pharma Joint Working Group and on behalf of the NCRI CTRad Academia-Pharma Joint Working Group
Nature reviews. Clinical oncology, ISSN 1759-4774, 10/2016, Volume 13, Issue 10, pp. 627 - 642
Life Sciences & Biomedicine | Oncology | Science & Technology | Cell Hypoxia - radiation effects | Humans | Patient Participation | Treatment Outcome | Combined Modality Therapy | Drug Approval | Radiation Dosage | Quality Assurance, Health Care | Neoplasms - drug therapy | Radiation Tolerance - radiation effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Neoplasms - radiotherapy | Clinical Trials as Topic - methods | Quality of Health Care | Patient Education as Topic | Evaluation | Chemotherapy | Care and treatment | Innovations | Drug therapy, Combination | Radiotherapy | Cancer | Index Medicus
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3. Full Text Light‐Activated Hypoxia‐Responsive Nanocarriers for Enhanced Anticancer Therapy
by Qian, Chenggen and Yu, Jicheng and Chen, Yulei and Hu, Quanyin and Xiao, Xuanzhong and Sun, Wujin and Wang, Chao and Feng, Peijian and Shen, Qun‐Dong and Gu, Zhen
Advanced materials (Weinheim), ISSN 0935-9648, 05/2016, Volume 28, Issue 17, pp. 3313 - 3320
hypoxia‐responsive | nanomedicine | drug delivery | photodynamic therapy | conjugated polymers | hypoxia-responsive | Materials Science | Materials Science, Multidisciplinary | Physics, Condensed Matter | Science & Technology - Other Topics | Chemistry, Physical | Physics | Science & Technology | Physics, Applied | Physical Sciences | Chemistry | Nanoscience & Nanotechnology | Technology | Chemistry, Multidisciplinary | Doxorubicin - therapeutic use | Optical Imaging | Polyvinyl Alcohol - chemistry | Nanoparticles - chemistry | Humans | Transplantation, Heterologous | Antineoplastic Agents - therapeutic use | Doxorubicin - chemistry | Drug Carriers - chemistry | Cell Hypoxia | Singlet Oxygen - metabolism | Light | Antineoplastic Agents - pharmacology | Cell Survival - drug effects | Microscopy, Electron, Transmission | Antineoplastic Agents - chemistry | Neoplasms - diagnostic imaging | Neoplasms - drug therapy | Microscopy, Confocal | Animals | Singlet Oxygen - chemistry | Mice, Nude | Mice | HeLa Cells | Neoplasms - pathology | Doxorubicin - pharmacology | Hydrogen-Ion Concentration | Drugs | Antimitotic agents | Care and treatment | Drug delivery systems | Antineoplastic agents | Vehicles | Cancer | Index Medicus | Therapy | Singlet oxygen | Effectiveness | Hypoxia | Nanostructure | Guidelines | Tumors | Anticancer properties | conjugated polymer
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4. Full Text Is there a future for andrographolide to be an anti-inflammatory drug? Deciphering its major mechanisms of action
by Tan, W.S. Daniel and Liao, Wupeng and Zhou, Shuo and Wong, W.S. Fred
Biochemical pharmacology, ISSN 0006-2952, 09/2017, Volume 139, pp. 71 - 81
Hepatitis | NF-κB | Autoimmune | Neurodegeneration | Nrf2 | Asthma | Liver Cirrhosis - immunology | Humans | Drugs, Investigational - therapeutic use | NF-E2-Related Factor 2 - agonists | Protective Agents - chemistry | Neurodegenerative Diseases - drug therapy | Hepatitis - drug therapy | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Hepatitis - metabolism | Pneumonia - immunology | Autoimmune Diseases - metabolism | Autoimmune Diseases - drug therapy | Diterpenes - pharmacology | Chemical and Drug Induced Liver Injury - prevention & control | NF-kappa B p50 Subunit - antagonists & inhibitors | NF-kappa B p50 Subunit - metabolism | Autoimmune Diseases - prevention & control | Chemical and Drug Induced Liver Injury - immunology | Signal Transduction - drug effects | Chemical and Drug Induced Liver Injury - metabolism | Models, Biological | NF-E2-Related Factor 2 - metabolism | Oxidative Stress - drug effects | Pneumonia - metabolism | Drugs, Investigational - adverse effects | Drugs, Investigational - pharmacology | Dermatitis - immunology | Neurodegenerative Diseases - prevention & control | Protective Agents - metabolism | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Hypoxia-Inducible Factor 1, alpha Subunit - antagonists & inhibitors | Protective Agents - therapeutic use | Neurodegenerative Diseases - immunology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Drugs, Investigational - chemistry | Hepatitis - prevention & control | Drug Design | Liver Cirrhosis - metabolism | Diterpenes - chemistry | Liver Cirrhosis - drug therapy | Diterpenes - therapeutic use | Liver Cirrhosis - prevention & control | Autoimmune Diseases - immunology | Dermatitis - prevention & control | Neurodegenerative Diseases - metabolism | Animals | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Pneumonia - drug therapy | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | NF-kappa B p50 Subunit - chemistry | Hepatitis - immunology | Diterpenes - adverse effects | Dermatitis - drug therapy | Dermatitis - metabolism | Antioxidants | Medical colleges | Lead compounds | Drug discovery | Anti-inflammatory drugs | Analysis | Index Medicus
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5. Full Text Nanoparticles for modulating tumor microenvironment to improve drug delivery and tumor therapy
by Yang, Shu and Gao, Huile
Pharmacological research, ISSN 1043-6618, 12/2017, Volume 126, pp. 97 - 108
Nanoparticles | Hypoxia | Drug delivery | Tumor microenvironment | Tumor associated fibroblasts | Tumor-associated macrophages | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Carcinogenesis - drug effects | Tumor Microenvironment - drug effects | Animals | Nanoparticles - chemistry | Fibroblasts - drug effects | Humans | Macrophages - drug effects | Nanoparticles - administration & dosage | Drug Delivery Systems - methods | Neoplasms - drug therapy | Drugs | Drug delivery systems | Development and progression | Metastasis | Permeability | Drug therapy | Macrophages | Vehicles | Index Medicus
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