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PLoS Genetics, ISSN 1553-7390, 09/2010, Volume 6, Issue 9, pp. e1001116 - e1001116
Journal Article
Journal Article
Journal of Pathology, ISSN 0022-3417, 2005, Volume 206, Issue 3, pp. 291 - 304
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2007, Volume 117, Issue 12, pp. 3660 - 3663
in this issue of the JCI, two reports provide intriguing new information on the role of the inflammatory cytokine IL-6 in breast and lung cancer. The study by... 
BREAST-CANCER | MEDICINE, RESEARCH & EXPERIMENTAL | LUNG-CANCER | PATHWAY | STAT3 | NOTCH | STEM/PROGENITOR CELLS | GROWTH-FACTOR | INTERLEUKIN-6 | IDENTIFICATION | TUMORIGENESIS | Receptor, Epidermal Growth Factor - genetics | Transcription, Genetic - drug effects | Interleukin-6 - antagonists & inhibitors | Carbonic Anhydrases - biosynthesis | Cytokine Receptor gp130 - genetics | Receptors, Notch - metabolism | Humans | Lung Neoplasms - metabolism | Antigens, Neoplasm - biosynthesis | Spheroids, Cellular - pathology | Neoplasm Proteins - pharmacology | Receptors, Notch - genetics | Janus Kinases - metabolism | RNA, Messenger - metabolism | Serrate-Jagged Proteins | Phosphorylation - drug effects | Neoplasm Proteins - genetics | Interleukin-6 - metabolism | Gene Expression Regulation, Neoplastic - genetics | STAT3 Transcription Factor - genetics | Cytokine Receptor gp130 - metabolism | Interleukin-6 - genetics | Membrane Proteins - genetics | Spheroids, Cellular - metabolism | Enzyme Inhibitors - pharmacology | Mammary Glands, Human - pathology | Lung Neoplasms - therapy | Signal Transduction - genetics | Autocrine Communication - genetics | Breast Neoplasms - genetics | RNA, Neoplasm - biosynthesis | Signal Transduction - drug effects | Mice, Nude | Cell Line, Tumor | RNA, Neoplasm - genetics | Stem Cells - pathology | Carcinoma - genetics | Mice | Mutation | Transcription, Genetic - genetics | Cell Hypoxia - genetics | Calcium-Binding Proteins - genetics | Neoplasm Transplantation | Carbonic Anhydrases - genetics | Lung Neoplasms - pathology | Autocrine Communication - drug effects | Mammary Glands, Human - metabolism | Neoplasm Proteins - metabolism | Stem Cells - metabolism | Breast Neoplasms - metabolism | Breast Neoplasms - therapy | Intercellular Signaling Peptides and Proteins - metabolism | Receptor, Epidermal Growth Factor - metabolism | Female | Membrane Proteins - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Carcinoma - pathology | STAT3 Transcription Factor - metabolism | Carbonic Anhydrase IX | Calcium-Binding Proteins - metabolism | Lung Neoplasms - genetics | Antigens, Neoplasm - genetics | Cell Hypoxia - drug effects | Janus Kinases - genetics | Neoplasm Invasiveness | RNA, Messenger - genetics | RNA, Small Interfering - pharmacology | Intercellular Signaling Peptides and Proteins - genetics | Up-Regulation - genetics | Up-Regulation - drug effects | Animals | Interleukin-6 - pharmacology | Breast Neoplasms - pathology | Interleukin-6 - biosynthesis | Carcinoma - therapy | Receptor, Notch3 | Carcinoma - metabolism | Antagonists (Biochemistry) | Epithelial tumors | Dosage and administration | Diagnosis | Research | Drug therapy | Health aspects | Interleukin-6 | Index Medicus | Abridged Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2009, Volume 4, Issue 6, pp. e5767 - e5767
Journal Article
Carcinogenesis, ISSN 0143-3334, 05/2013, Volume 34, Issue 5, pp. 962 - 973
Journal Article
Oncogene, ISSN 0950-9232, 02/2015, Volume 34, Issue 7, pp. 826 - 837
Nucleolin (NCL) participates in DNA transcription, ribosomal biogenesis and the regulation of RNA stability. However, the contribution of NCL to tumor... 
TARGET | APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | LUNG-CANCER | IN-VITRO | ONCOLOGY | GASTRIC-CARCINOMA | PROSTATE-CANCER CELLS | GENETICS & HEREDITY | PROTEINS | BINDING | PROGRESSION | MATRILYSIN MMP-7 | Kruppel-Like Factor 6 | Proto-Oncogene Proteins c-cbl - metabolism | Humans | Lung Neoplasms - metabolism | Male | RNA, Messenger - metabolism | Autoantigens - genetics | RNA, Neoplasm - metabolism | Neoplasm Metastasis | Matrix Metalloproteinase 7 - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Matrix Metalloproteinase 9 - genetics | Proteolysis | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Cell Cycle Proteins - metabolism | Receptor Protein-Tyrosine Kinases - metabolism | RNA Stability - genetics | Mice, Nude | RNA, Neoplasm - genetics | Mice | Kruppel-Like Transcription Factors - genetics | RNA-Binding Proteins - metabolism | RNA-Binding Proteins - genetics | Autoantigens - metabolism | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Phosphoproteins - metabolism | Kruppel-Like Transcription Factors - metabolism | Cell Cycle Proteins - genetics | Female | Nuclear Proteins - genetics | Lung Neoplasms - genetics | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins c-cbl - genetics | Matrix Metalloproteinase 9 - biosynthesis | RNA, Messenger - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Phosphoproteins - genetics | Transcription Factors - genetics | Gene Expression Regulation, Enzymologic | Proteins - genetics | Transcription Factors - metabolism | Matrix Metalloproteinase 7 - genetics | Animals | Proteins - metabolism | Receptor Protein-Tyrosine Kinases - genetics | Adaptor Proteins, Signal Transducing - genetics | Aged | Adaptor Proteins, Signal Transducing - metabolism | RNA | Phosphoproteins | Physiological aspects | Development and progression | Genetic aspects | Health aspects | Metalloproteins | Tumors | Signal transduction | Protein expression | Tumorigenesis | Lung cancer | Index Medicus
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 08/2010, Volume 19, Issue 15, pp. 3011 - 3020
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2012, Volume 287, Issue 51, pp. 42695 - 42707
Development of metastatic disease accounts for the vast majority of cancer-related deaths. Nevertheless, few treatments exist that are designed to specifically... 
ACTIVATION | ZEB1 | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENES | ATM | REGULATORS | HYPOXIA | MIR-200 FAMILY | CANCER | EXPRESSION | Carcinoma, Ductal, Breast - genetics | Cell Proliferation | Epithelial Cells - metabolism | Cadherins - metabolism | Polycomb Repressive Complex 1 - metabolism | Humans | Gene Expression Regulation, Neoplastic | Genetic Loci - genetics | Molecular Sequence Data | MicroRNAs - metabolism | Cell Shape - genetics | Epithelial-Mesenchymal Transition - genetics | Breast - metabolism | DNA-Binding Proteins - metabolism | Base Sequence | Tumor Suppressor Proteins - genetics | Cell Cycle Proteins - genetics | Carcinoma, Ductal, Breast - pathology | Female | Cadherins - genetics | Nuclear Proteins - genetics | Breast - pathology | Protein-Serine-Threonine Kinases - metabolism | Multigene Family - genetics | Tumor Suppressor Proteins - metabolism | Neoplasm Invasiveness | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Nuclear Proteins - metabolism | Signal Transduction - genetics | Ataxia Telangiectasia Mutated Proteins | DNA-Binding Proteins - genetics | Genomic Imprinting - genetics | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Models, Biological | Twist-Related Protein 1 - genetics | Cell Line, Tumor | MicroRNAs - genetics | Twist-Related Protein 1 - metabolism | Index Medicus | Molecular Bases of Disease | MicroRNA | Ataxia Telangiectasia Mutated | DLKI-DIO3 | Tumor Metastases | Epithelial to Mesenchymal Transition | Breast Cancer | EMT | TWIST
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 2007, Volume 117, Issue 12, pp. 3988 - 4002
High serum levels of IL-6 correlate with poor outcome in breast cancer patients. However, no data are available on the relationship between IL-6 and mammary... 
CANCER-CELLS | INITIATING CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | GENE SIGNATURE | CARBONIC-ANHYDRASE-IX | STEM-CELLS | STEM/PROGENITOR CELLS | SELF-RENEWAL | GROWTH-FACTOR | EXTRACELLULAR PH | IN-VITRO PROPAGATION | Carbonic Anhydrases - biosynthesis | Carcinoma, Ductal - genetics | Receptors, Notch - metabolism | Carbonic Anhydrases - genetics | Carcinoma, Ductal - pathology | Humans | Antigens, Neoplasm - biosynthesis | Spheroids, Cellular - pathology | Neoplasm Proteins - pharmacology | Receptors, Notch - genetics | Autocrine Communication - drug effects | Mammary Glands, Human - metabolism | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | Stem Cells - metabolism | Breast Neoplasms - metabolism | Serrate-Jagged Proteins | Female | Carcinoma, Ductal - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Interleukin-6 - metabolism | Gene Expression Regulation, Neoplastic - genetics | Carbonic Anhydrase IX | Jagged-1 Protein | Antigens, Neoplasm - genetics | Cell Hypoxia - drug effects | Calcium-Binding Proteins | Interleukin-6 - genetics | Neoplasm Invasiveness | Intercellular Signaling Peptides and Proteins | RNA, Messenger - genetics | Spheroids, Cellular - metabolism | Mammary Glands, Human - pathology | Up-Regulation - genetics | Autocrine Communication - genetics | Membrane Proteins | Up-Regulation - drug effects | Breast Neoplasms - genetics | RNA, Neoplasm - biosynthesis | Interleukin-6 - pharmacology | Breast Neoplasms - pathology | Cell Line, Tumor | RNA, Neoplasm - genetics | Stem Cells - pathology | Receptor, Notch3 | Cell Hypoxia - genetics | Breast cancer | Genetic aspects | Research | Gene expression | Health aspects | Interleukin-6 | Index Medicus | Abridged Index Medicus
Journal Article