X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (907) 907
humans (742) 742
animals (702) 702
hypoxia (481) 481
hypoxia-inducible factor 1, alpha subunit - metabolism (419) 419
mice (313) 313
cell biology (245) 245
biochemistry & molecular biology (241) 241
signal transduction (233) 233
hypoxia-inducible factor 1, alpha subunit - genetics (218) 218
male (217) 217
angiogenesis (214) 214
expression (209) 209
cancer (200) 200
hypoxia-inducible factor (184) 184
article (175) 175
endothelial growth-factor (168) 168
inflammation (165) 165
gene expression (161) 161
gene-expression (160) 160
hypoxia-inducible factors (158) 158
vascular endothelial growth factor (156) 156
activation (154) 154
female (153) 153
apoptosis (150) 150
cell line, tumor (150) 150
rats (149) 149
physiological aspects (148) 148
proteins (148) 148
oncology (147) 147
hypoxia-inducible factor-1-alpha (144) 144
cells, cultured (141) 141
research (128) 128
oxidative stress (120) 120
hypoxia-inducible factor 1 (117) 117
hypoxia-inducible factor-1 (115) 115
rodents (111) 111
kinases (110) 110
transcription factors (110) 110
pharmacology & pharmacy (106) 106
medicine (105) 105
nf-kappa-b (102) 102
signal transduction - drug effects (102) 102
cell hypoxia (101) 101
vascular endothelial growth factor a - metabolism (100) 100
cell line (99) 99
research article (98) 98
hypoxia-inducible factor 1 - metabolism (97) 97
multidisciplinary sciences (97) 97
physiology (97) 97
analysis (96) 96
medicine, research & experimental (94) 94
ischemia (93) 93
metabolism (92) 92
immunology (91) 91
tumors (91) 91
cells (89) 89
mice, inbred c57bl (88) 88
endocrinology & metabolism (87) 87
up-regulation (86) 86
health aspects (85) 85
neurosciences (85) 85
disease models, animal (81) 81
genetic aspects (81) 81
hif-1α (81) 81
biology (79) 79
science (76) 76
phosphorylation (74) 74
cell proliferation (72) 72
development and progression (72) 72
blotting, western (71) 71
rna, messenger - metabolism (71) 71
macrophages (70) 70
factor-i (69) 69
reactive oxygen species - metabolism (68) 68
biomedicine (67) 67
gene expression regulation (66) 66
vegf (66) 66
hif-1 (65) 65
hif-1-alpha (65) 65
inhibition (65) 65
rats, sprague-dawley (65) 65
review (65) 65
in-vivo (64) 64
care and treatment (63) 63
hypoxia - metabolism (62) 62
vascular endothelial growth factor a - genetics (61) 61
hif-1 alpha (60) 60
mice, knockout (59) 59
genes (58) 58
in-vitro (58) 58
oxygen (58) 58
oxygen - metabolism (58) 58
inducible factor-i (57) 57
nitric-oxide synthase (57) 57
rna, messenger - genetics (57) 57
disease (55) 55
growth (55) 55
stem cells (55) 55
hypoxia-inducible factor 1, alpha subunit - antagonists & inhibitors (54) 54
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Journal Article
Journal of Molecular Medicine, ISSN 0946-2716, 9/2012, Volume 90, Issue 9, pp. 1079 - 1089
Hypoxia inducible factor-1 (HIF-1) is a transcription factor that is a major regulator of energy homeostasis and cellular adaptation to low oxygen stress.... 
Human Genetics | Bacterial infection | Biomedicine | Internal Medicine | Innate immunity | Molecular Medicine | Antibiotic-resistant bacteria | Hypoxia inducible factor-1 (HIF-1) | Staphylococcus aureus | MEDICINE, RESEARCH & EXPERIMENTAL | OXIDATIVE STRESS | SERIES | PROLYL HYDROXYLASE INHIBITORS | TISSUE | RESISTANT STAPHYLOCOCCUS-AUREUS | ENDOTHELIAL-CELLS | GENETICS & HEREDITY | HIF-1-ALPHA | DIFFERENTIATION | OXYGEN HOMEOSTASIS | EXPRESSION | Skin - microbiology | Skin Diseases, Bacterial - immunology | Humans | Anti-Bacterial Agents - therapeutic use | Hypoxia-Inducible Factor 1 - agonists | Female | Keratinocytes - microbiology | Skin - immunology | Cell Line | Immunity, Innate - drug effects | Staphylococcal Infections - immunology | Phagocytes - drug effects | Hypoxia-Inducible Factor 1 - immunology | Piperazines - therapeutic use | Phagocytes - immunology | Piperazines - pharmacology | Keratinocytes - immunology | Skin Diseases, Bacterial - prevention & control | Animals | Keratinocytes - drug effects | Phagocytes - microbiology | Staphylococcal Infections - prevention & control | Staphylococcus aureus - immunology | Mice | Pyridones - therapeutic use | Staphylococcus aureus - drug effects | Pyridones - pharmacology | Skin - drug effects | Adaptations | Pathogens | Animal models | Antimicrobial activity | Hypoxia-inducible factor 1 | Oxygen | Transcription factors | Immune response | Keratinocytes | Drug resistance | Stress | Infection | Energy balance | Phagocytes | Abscesses | Antibacterial activity | Skin
Journal Article
Journal Article
Inflammatory Bowel Diseases, ISSN 1078-0998, 2015, Volume 21, Issue 2, pp. 267 - 275
Journal Article
Journal of Antibiotics, ISSN 0021-8820, 10/2016, Volume 69, Issue 10, pp. 747 - 753
In the course of our screening for activators of hypoxia-inducible factor (HIF), A-503451 A and virantmycin were isolated from the cultured broth of an... 
Streptomyces - metabolism | Streptomyces - genetics | Humans | Quinolines - chemistry | Hypoxia-Inducible Factor 1 - agonists | Molecular Structure | Fermentation | Genes, Reporter | Hep G2 Cells
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 09/2016, Volume 6, Issue 1, pp. 33274 - 33274
Bacterial resistance against classical antibiotics is a growing problem and the development of new antibiotics is limited. Thus, novel alternatives to... 
MACROPHAGES | RELEVANCE | MULTIDISCIPLINARY SCIENCES | VITAMIN-D-RECEPTOR | DEFENSINS | ANTIMICROBIAL PEPTIDES | MUTATIONS | INDUCTION | EXPRESSION | CATHELICIDIN LL-37 | INNATE IMMUNITY | Job Syndrome - immunology | RNA, Small Interfering - genetics | Job Syndrome - genetics | Luciferases - metabolism | Humans | STAT3 Transcription Factor - agonists | Transcriptional Activation | Hypoxia-Inducible Factor 1, alpha Subunit - antagonists & inhibitors | Cathelicidins - genetics | Luciferases - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Leukocytes, Mononuclear - immunology | HEK293 Cells | Benzamides - pharmacology | Hypoxia-Inducible Factor 1, alpha Subunit - agonists | Genes, Reporter | Macrophages - immunology | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Promoter Regions, Genetic | Leukocytes, Mononuclear - drug effects | Macrophages - pathology | Signal Transduction | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Antimicrobial Cationic Peptides | HT29 Cells | Cathelicidins - metabolism | Cathelicidins - agonists | Protein Binding | Histone Deacetylase Inhibitors - pharmacology | Leukocytes, Mononuclear - cytology | Macrophages - drug effects | Job Syndrome - pathology | Pyridines - pharmacology | Primary Cell Culture | STAT3 Transcription Factor - antagonists & inhibitors | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 10/2016, Volume 99, pp. 498 - 507
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 10, pp. 3562 - 3587
Multidrug resistance (MDR) is a major obstacle in cancer treatment due to the ability of tumor cells to efflux chemotherapeutics via drug transporters (e.g.... 
DI-2-PYRIDYLKETONE | ISONICOTINOYL HYDRAZONE CLASS | IRON CHELATORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG-RESISTANCE | MULTIDRUG-RESISTANCE | ANTITUMOR-ACTIVITY | HYPOXIA | CANCER | MODULATION | MEMBRANE PERMEABILIZATION | Neoplasms - metabolism | Apoptosis - drug effects | Drug Resistance, Multiple - drug effects | Humans | Hypoxia-Inducible Factor 1, alpha Subunit - antagonists & inhibitors | Neoplasm Proteins - antagonists & inhibitors | ATP Binding Cassette Transporter, Subfamily B - agonists | Protein Transport - drug effects | Neoplasm Proteins - metabolism | Antineoplastic Agents - metabolism | Cell Hypoxia | Organelle Biogenesis | Lysosomes - metabolism | RNA Interference | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | ATP Binding Cassette Transporter, Subfamily B - genetics | Antineoplastic Agents - pharmacology | Biological Transport - drug effects | Doxorubicin - metabolism | Thiosemicarbazones - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - agonists | Lysosomes - drug effects | Tumor Microenvironment - drug effects | Tetrahydroisoquinolines - pharmacology | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Hydrogen Peroxide - pharmacology | ATP Binding Cassette Transporter, Subfamily B - metabolism | Neoplasms - drug therapy | Neoplasm Proteins - agonists | ATP Binding Cassette Transporter, Subfamily B - antagonists & inhibitors | Models, Biological | Acridines - pharmacology | Cell Line, Tumor | Cell Proliferation - drug effects | Neoplasms - pathology | Doxorubicin - pharmacology | Drug Resistance, Neoplasm - drug effects | P-glycoprotein | ABCB1 | drug transport | tumor micro-environment | drug delivery | drug resistance | tumor micro-environmental stress | lysosome | Cell Biology
Journal Article
The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 12/2017, Volume 363, Issue 3, pp. 336 - 347
Decreased erythropoietin (EPO) production, shortened erythrocyte survival, and other factors reducing the response to EPO contribute to anemia in patients who... 
Humans | Male | Hypoxia-Inducible Factor-Proline Dioxygenases - antagonists & inhibitors | Enzyme Inhibitors - administration & dosage | Toxicity Tests, Chronic | Basic Helix-Loop-Helix Transcription Factors - metabolism | Barbiturates - pharmacology | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - chemistry | Erythropoietin - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - agonists | Glycine - administration & dosage | Barbiturates - administration & dosage | Enzyme Inhibitors - adverse effects | Glycine - pharmacokinetics | Basic Helix-Loop-Helix Transcription Factors - agonists | Isoenzymes - genetics | Enzyme Inhibitors - pharmacology | Hypoxia-Inducible Factor-Proline Dioxygenases - genetics | Recombinant Proteins - chemistry | Hematinics - adverse effects | Rats, Sprague-Dawley | Erythropoietin - genetics | Glycine - pharmacology | Protein Stability - drug effects | Cell Line, Tumor | Mice | Barbiturates - pharmacokinetics | Glycine - analogs & derivatives | Drugs, Investigational - adverse effects | Drugs, Investigational - pharmacology | Glycine - adverse effects | Drugs, Investigational - pharmacokinetics | Erythropoiesis - drug effects | Dose-Response Relationship, Drug | Enzyme Inhibitors - pharmacokinetics | Isoenzymes - metabolism | Female | Hematinics - pharmacokinetics | Barbiturates - adverse effects | Recombinant Proteins - metabolism | Hematinics - pharmacology | Hematinics - administration & dosage | Erythropoietin - agonists | Animals | Hypoxia-Inducible Factor-Proline Dioxygenases - metabolism | Dogs | Drugs, Investigational - administration & dosage | Isoenzymes - antagonists & inhibitors | Basic Helix-Loop-Helix Transcription Factors - chemistry | Index Medicus
Journal Article