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oxygen - metabolism (141) 141
hypoxia - metabolism (140) 140
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cell proliferation (139) 139
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gene expression regulation (129) 129
vascular endothelial growth factor a - metabolism (129) 129
health aspects (128) 128
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hypoxia-inducible factor 1, alpha subunit - deficiency (122) 122
phosphorylation (120) 120
basic helix-loop-helix transcription factors - metabolism (114) 114
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hypoxia-inducible factor 1, alpha subunit - physiology (102) 102
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Cancer Research, ISSN 0008-5472, 10/2010, Volume 70, Issue 19, pp. 7465 - 7475
Journal Article
Nature Immunology, ISSN 1529-2908, 2013, Volume 14, Issue 11, pp. 1173 - 1182
Cytolytic activity by CD8(+) cytotoxic T lymphocytes (CTLs) is a powerful strategy for the elimination of intracellular pathogens and tumor cells. The... 
SELECTIVE EXPRESSION | GENE | MEMORY | INFLAMMATION | DISEASE | TUMOR-SUPPRESSOR | CHUVASH POLYCYTHEMIA | IMMUNOLOGY | CHRONIC VIRAL-INFECTION | CANCER | EXHAUSTION | Lymphocytic choriomeningitis virus - immunology | Oxygen - pharmacology | Transcription, Genetic - drug effects | Cell Hypoxia - immunology | Humans | Lymphocytic Choriomeningitis - immunology | Hypoxia-Inducible Factor 1, alpha Subunit - deficiency | T-Lymphocytes, Cytotoxic - pathology | Melanoma, Experimental - immunology | Skin Neoplasms - mortality | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Basic Helix-Loop-Helix Transcription Factors - deficiency | Melanoma, Experimental - virology | Hypoxia-Inducible Factor 1, alpha Subunit - immunology | Skin Neoplasms - pathology | T-Lymphocytes, Cytotoxic - immunology | Lymphocytic Choriomeningitis - virology | Basic Helix-Loop-Helix Transcription Factors - genetics | Melanoma, Experimental - mortality | Skin Neoplasms - immunology | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Lymphocytic Choriomeningitis - pathology | Melanoma, Experimental - pathology | Mice, Knockout | Gene Expression Regulation - drug effects | Von Hippel-Lindau Tumor Suppressor Protein - immunology | Animals | Signal Transduction - drug effects | Skin Neoplasms - virology | Survival Analysis | Basic Helix-Loop-Helix Transcription Factors - immunology | Mice | Immunologi inom det medicinska området | Klinisk medicin | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Cancer och onkologi
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2012, Volume 122, Issue 4, pp. 1427 - 1443
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 2015, Volume 35, Issue 11, pp. 2316 - 2325
Although immune responses drive the pathogenesis of atherosclerosis, mechanisms that control antigen-presenting cell (APC)-mediated immune activation in... 
atherosclerosis | leukocytes | antigen-presenting cells | diet | high-fat | inflammation | ACTIVATION | DENDRITIC CELLS | INDUCIBLE FACTOR 1-ALPHA | MACROPHAGES | MURINE ATHEROSCLEROSIS | HYPOXIA | NEGATIVE REGULATOR | IMMUNE-RESPONSES | IN-VIVO | LIPOPOLYSACCHARIDE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Atherosclerosis - genetics | Coculture Techniques | Humans | Male | Aorta - metabolism | Aortic Diseases - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - deficiency | CD11c Antigen - metabolism | CD11c Antigen - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | T-Lymphocytes, Helper-Inducer - immunology | Diet, High-Fat | Receptors, LDL - deficiency | Carotid Artery Diseases - metabolism | Macrophages - immunology | STAT3 Transcription Factor - metabolism | Aortic Diseases - pathology | Disease Models, Animal | Receptors, LDL - genetics | Antigen-Presenting Cells - metabolism | Atherosclerosis - pathology | Atherosclerosis - immunology | T-Lymphocytes, Helper-Inducer - metabolism | Signal Transduction | Aortic Diseases - immunology | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Lymphocyte Activation | Mice, Inbred C57BL | Cells, Cultured | Aorta - immunology | Interleukin-12 - metabolism | Plaque, Atherosclerotic | Antigen-Presenting Cells - immunology | Atherosclerosis - metabolism | Mice, Knockout | Aorta - pathology | Aortic Diseases - genetics | Macrophages - metabolism | Phenotype | Animals
Journal Article
Circulation Research, ISSN 0009-7330, 06/2015, Volume 117, Issue 1, pp. 65 - 79
Hypoxia inducible factors (HIFs) are α/β heterodimeric transcription factors that direct multiple cellular and systemic responses in response to changes in... 
hypoxia | dioxygenases | prolyl hydroxylases | hypoxia inducible factor | CARDIAC OUTFLOW TRACT | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | PULMONARY ARTERIAL-HYPERTENSION | HYPOXIA-INDUCIBLE-FACTOR | FACTOR-I | ISCHEMIA-REPERFUSION INJURY | GENE-ENVIRONMENT INTERACTION | HIGH-ALTITUDE ADAPTATION | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | CAROTID-BODY | HEMATOLOGY | Adaptation, Physiological | Polycythemia - genetics | Heart Defects, Congenital - embryology | Cardiovascular Diseases - drug therapy | Heart - embryology | Humans | Hypoxia-Inducible Factor-Proline Dioxygenases - antagonists & inhibitors | Cardiovascular Diseases - enzymology | Oxygen - metabolism | Hypoxia - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - deficiency | Hypoxia-Inducible Factor-Proline Dioxygenases - deficiency | Cell Hypoxia | Repressor Proteins - physiology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Heart Defects, Congenital - enzymology | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Mixed Function Oxygenases - physiology | Von Hippel-Lindau Tumor Suppressor Protein - metabolism | Basic Helix-Loop-Helix Transcription Factors - deficiency | Basic Helix-Loop-Helix Transcription Factors - genetics | Hypoxia-Inducible Factor-Proline Dioxygenases - physiology | Cardiovascular Diseases - metabolism | Hydroxylation | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Hypoxia-Inducible Factor-Proline Dioxygenases - genetics | Hypertension, Pulmonary - metabolism | Cardiovascular System - enzymology | Animals | Iron - physiology | Polycythemia - enzymology | Cardiovascular System - metabolism | Ischemic Preconditioning, Myocardial | Protein Isoforms | Mice | Protein Processing, Post-Translational | Altitude | Hypoxia | oxygen sensing | HIF | 2-oxoglutarate oxygenase | hydroxylase
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 02/2014, Volume 189, Issue 3, pp. 314 - 324
Journal Article
Journal Article
Journal Article
Journal Article