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Circulation research, ISSN 1524-4571, 06/2015, Volume 117, Issue 1, pp. 65 - 79
.... The oxygen sensitive signal is generated by a series of iron and 2-oxoglutarate–dependent dioxygenases that catalyze post-translational hydroxylation of specific prolyl and asparaginyl residues in HIFα... 
hypoxia | dioxygenases | prolyl hydroxylases | hypoxia inducible factor | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Adaptation, Physiological | Polycythemia - genetics | Heart Defects, Congenital - embryology | Cardiovascular Diseases - drug therapy | Heart - embryology | Humans | Hypoxia-Inducible Factor-Proline Dioxygenases - antagonists & inhibitors | Cardiovascular Diseases - enzymology | Oxygen - metabolism | Hypoxia - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - deficiency | Hypoxia-Inducible Factor-Proline Dioxygenases - deficiency | Cell Hypoxia | Repressor Proteins - physiology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Heart Defects, Congenital - enzymology | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Mixed Function Oxygenases - physiology | Von Hippel-Lindau Tumor Suppressor Protein - metabolism | Basic Helix-Loop-Helix Transcription Factors - deficiency | Basic Helix-Loop-Helix Transcription Factors - genetics | Hypoxia-Inducible Factor-Proline Dioxygenases - physiology | Cardiovascular Diseases - metabolism | Hydroxylation | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Hypoxia-Inducible Factor-Proline Dioxygenases - genetics | Hypertension, Pulmonary - metabolism | Cardiovascular System - enzymology | Animals | Iron - physiology | Polycythemia - enzymology | Cardiovascular System - metabolism | Ischemic Preconditioning, Myocardial | Protein Isoforms | Mice | Protein Processing, Post-Translational | Altitude | Index Medicus | Hypoxia | oxygen sensing | HIF | 2-oxoglutarate oxygenase | hydroxylase
Journal Article
EMBO reports, ISSN 1469-221X, 10/2015, Volume 16, Issue 10, pp. 1394 - 1408
Journal Article
Nature (London), ISSN 1476-4687, 02/2012, Volume 483, Issue 7390, pp. 484 - 488
Journal Article
Journal of Applied Physiology, ISSN 8750-7587, 04/2014, Volume 116, Issue 7, pp. 893 - 904
Journal Article
Cancer cell, ISSN 1535-6108, 01/2011, Volume 19, Issue 1, pp. 17 - 30
...-KG-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases... 
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Dioxygenases - metabolism | Histone Demethylases - antagonists & inhibitors | Gene Expression - genetics | Caenorhabditis elegans Proteins - chemistry | Humans | Ketoglutaric Acids - chemistry | Glioma - genetics | F-Box Proteins | Oxidoreductases, N-Demethylating - antagonists & inhibitors | Ketoglutaric Acids - pharmacology | Cytosine - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Glutarates - chemistry | Oxidoreductases, N-Demethylating - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Glioma - enzymology | Endostatins - metabolism | Models, Molecular | Isocitrate Dehydrogenase - genetics | Histone Demethylases - metabolism | Dioxygenases - antagonists & inhibitors | Amino Acid Substitution - physiology | Procollagen-Proline Dioxygenase - genetics | Cell Line, Tumor | Isocitrate Dehydrogenase - metabolism | Glutarates - pharmacology | Histones - metabolism | Jumonji Domain-Containing Histone Demethylases - metabolism | Caenorhabditis elegans - enzymology | Cytosine - analogs & derivatives | Gene Expression - drug effects | Caenorhabditis elegans Proteins - metabolism | Isocitrate Dehydrogenase - antagonists & inhibitors | Glioma - metabolism | Procollagen-Proline Dioxygenase - metabolism | DNA-Binding Proteins - metabolism | Mixed Function Oxygenases | Biocatalysis - drug effects | Jumonji Domain-Containing Histone Demethylases - antagonists & inhibitors | Jumonji Domain-Containing Histone Demethylases - chemistry | Procollagen-Proline Dioxygenase - antagonists & inhibitors | Ketoglutaric Acids - metabolism | Oxalates - pharmacology | Binding, Competitive | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Catalytic Domain | Proto-Oncogene Proteins - genetics | Hypoxia-Inducible Factor-Proline Dioxygenases | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Animals | 5-Methylcytosine - metabolism | Caenorhabditis elegans Proteins - antagonists & inhibitors | Glutarates - metabolism | Index Medicus
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 05/2016, Volume 126, Issue 5, pp. 1926 - 1938
Journal Article