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by Jiang, LL and Lin, CY and Song, LB and Wu, JH and Chen, BX and Ying, Z and Fang, LS and Yan, X and He, M and Li, J and Li, MF
JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 01/2012, Volume 122, Issue 1, pp. 33 - 47
Constitutive activation of NF-kappa B is a frequent event in human cancers, playing important roles in cancer development and progression. In nontransformed... 
MALIGNANT GLIOMA | MEDICINE, RESEARCH & EXPERIMENTAL | STEM-CELLS | GLIOBLASTOMA | ANGIOGENESIS | GENES | NUCLEAR EXPORT SIGNAL | MICRORNA EXPRESSION | PATIENT SURVIVAL | CANCER | BRAIN-TUMORS
Journal Article
by Lei, XF and Bai, ZQ and Ye, FC and Xie, JP and Kim, CG and Huang, YF and Gao, SJ
NATURE CELL BIOLOGY, ISSN 1465-7392, 02/2010, Volume 12, Issue 2, pp. 193 - U232
Kaposi's sarcoma-associated herpesvirus (KSHV) is causally linked to several acquired immune deficiency syndrome-related malignancies, including Kaposi's... 
KAPOSIS-SARCOMA | PATHWAY | SARCOMA-ASSOCIATED HERPESVIRUS | LATENT | GENE-EXPRESSION | TARGETS | INFECTION | TRANSCRIPTIONAL PROGRAM | IDENTIFICATION | EPSTEIN-BARR-VIRUS | CELL BIOLOGY | viral latency and replication | NF-κB | microRNA | reverse genetics | KSHV
Journal Article
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 11/2017, Volume 92, p. 134
Journal Article
INTERNATIONAL IMMUNOPHARMACOLOGY, ISSN 1567-5769, 06/2017, Volume 47, pp. 126 - 133
Quercetin, a natural flavonoid, has been used as a nutritional supplement for its anti-inflammatory and antioxi-dative properties. Quercetin was reported to... 
TRANSCRIPTIONAL ACTIVATION | OXIDATIVE STRESS | KINASE | INJURY | Liver fibrosis | IMMUNOLOGY | RAT MODEL | FUZHENG HUAYU RECIPE | NF-kappa B | HEPATIC STELLATE CELLS | PATHWAY | Quercetin | IN-VIVO | PHARMACOLOGY & PHARMACY | p38 MAPK, apoptosis pathway | EXPRESSION
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 04/2017, Volume 429, Issue 7, p. 999
We recently discovered that I[kappa]B[alpha] enhances the rate of release of nuclear factor kappa B (NF[kappa]B) from DNA target sites in a process we have... 
Molecular dynamics | DNA
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2018, Volume 503, Issue 3, p. 1322
Ischemic stroke is an acute cerebrovascular disease due to poor blood flow to the brain. Nevertheless, there is still no effective therapy for it and the... 
Stroke (Disease) | Brain | COX-2 inhibitors | Enzymes | Interleukins | Inflammation | Mitogens | Protein kinases | Injuries
Journal Article
Life Sciences, ISSN 0024-3205, 02/2019, Volume 218, p. 147
Osteoarthritis (OA) is an inflammatory joint disease. USP14, a deubiquitinating enzyme critical for ubiquitin-mediated proteasomal protein degradation, is... 
Ubiquitin | Enzymes | Proteolysis
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 08/2015, Volume 427, Issue 17, p. 2748
Whereas ubiquitin-dependent degrons have been characterized in some detail, how proteins may be targeted to ubiquitin-independent proteasomal degradation... 
Ubiquitin
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 11/2009, Volume 106, Issue 46, pp. 19328 - 19333
A hallmark of the NF-kappa B transcription response to inflammatory cytokines is the remarkably rapid rate of robust activation and subsequent signal... 
COMPLEX | disordered proteins | transcription | MECHANISM | TEMPORAL CONTROL | binding kinetics | MULTIDISCIPLINARY SCIENCES | protein-DNA interaction | RAY CRYSTAL-STRUCTURE | NUCLEAR-LOCALIZATION | surface plasmon resonance | GENE-EXPRESSION | INHIBITOR | PROTEINS | TRANSCRIPTION FACTOR | BINDING
Journal Article
Journal of Theoretical Biology, ISSN 0022-5193, 02/2019, Volume 462, p. 479
The transcription factor NF-[kappa]B performs various cell functions, such as regulating proliferation and differentiation and blocking apoptosis, by inducing... 
Journal Article
Turkish journal of obstetrics and gynecology, ISSN 2149-9322, 12/2018, Volume 15, Issue 4, pp. 277 - 278
The rational of this study is based on evidence of the critical role of NF-кB, which mediates gene transcription of several protein involved in inflammation,... 
Endometriosis | Tumor necrosis factor-TNF | Phosphorylation | Cytokines | endometriotic implants | Letter to the Editor | deep infiltrating endometriosis | inhibitory kappa B
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 05/2017, Volume 802, pp. 7 - 19
Journal Article
Oncogene, ISSN 0950-9232, 06/2005, Volume 24, Issue 28, pp. 4486 - 4495
Recent studies indicate that natural isothiocyanates, such as sulforaphane (SFN) and phenethyl isothiocyanate ( PEITC) possess strong antitumor activities in... 
IKK | NF-κB | Phenethyl isothiocyanate | Sulforaphane | IκBα | sulforaphane | ACTIVATION | TYROSINE PHOSPHORYLATION | INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INFLAMMATORY STIMULI | DOWN-REGULATION | TERMINAL KINASE | CELL BIOLOGY | POTENT INDUCTION | phenethyl isothiocyanate | NF-kappa B | ONCOLOGY | I kappa B alpha | SIGNALING PATHWAY | GENETICS & HEREDITY | UP-REGULATION
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 04/2012, Volume 40, Issue 8, pp. 3548 - 3562
Journal Article
Nephrology Dialysis Transplantation, ISSN 0931-0509, 04/2006, Volume 21, Issue 4, pp. 889 - 897
Background. In a previous study we demonstrated the inhibitory effect of 1,25-dihydroxyvitamin D (1,25(OH)(2)D-3) and its less calcaemic analog 1,24(OH)(2)D-2... 
Tumour necrosis factor alpha | NFκB | Vitamin D | Macrophages | IκBα | ANALOG | vitamin D | TRANSCRIPTIONAL REPRESSION | NECROSIS-FACTOR-ALPHA | D-3 | INDUCTION | TRANSPLANTATION | macrophages | INHIBITION | I kappa B alpha | GENE-EXPRESSION | UROLOGY & NEPHROLOGY | C-JUN | PROMOTER | tumour necrosis factor alpha | NF kappa B
Journal Article