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International journal of cancer, ISSN 1097-0215, 12/2009, Volume 125, Issue 12, pp. 2863 - 2870
...‐κB (NFκB) by inducing phosphorylation and subsequent degradation of inhibitor of κB (IκB). We show here that NF... 
IκB | IKK | oncogenic transformation | PI‐3 kinase | NF‐κB | Akt | NF-κB | PI-3 kinase | Oncogenic transformation | Life Sciences & Biomedicine | Oncology | Science & Technology
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 10/2010, Volume 107, Issue 42, pp. 18103 - 18108
Journal Article
The international journal of biochemistry & cell biology, ISSN 1357-2725, 02/2018, Volume 95, pp. 108 - 112
...B dimers have thus far prevented the development of any clinically useful NF-κB inhibitor.•Emerging therapeutic approaches aim to achieve the cancer-selective inhibition of the NF... 
NF-κB | DTP3 | IKKβ | GADD45β | Cancer | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasms - metabolism | Cell Survival - drug effects | Molecular Targeted Therapy - adverse effects | NF-kappa B - antagonists & inhibitors | Drugs, Investigational - adverse effects | Drugs, Investigational - pharmacology | Apoptosis - drug effects | Humans | Drugs, Investigational - therapeutic use | NF-kappa B - metabolism | Neoplasm Proteins - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - chemistry | Neoplasm Proteins - metabolism | Neoplasms - drug therapy | Drugs, Investigational - chemistry | Animals | Molecular Targeted Therapy - trends | Signal Transduction - drug effects | Antineoplastic Agents - adverse effects | Models, Biological | Drug Design | Antineoplastic Agents - pharmacology | Neoplasms - pathology | Index Medicus | GBM, glioblastoma multiforme | SCF, SKP1-Cullin 1-F-box protein | MCL1, myeloid cell leukaemia sequence 1 | JNK, c-Jun N-terminal kinase | IL-1β, interleukin-1β | IκBα, nuclear factor of κ light polypeptide gene enhancer in B-cells inhibitor α | GADD45β, growth arrest and DNA damage inducible β | cFLIP, cellular FLICE-inhibitory protein | DIABLO, direct inhibitor of apoptosis protein (IAP)-binding protein with low pI | NF-κB, nuclear factor κ B (nuclear factor binding to the κ-light-chain-enhancer B site) | BCL-XL, B-cell lymphoma-extra large | DLBCL, diffuse large B-cell lymphoma | RAS, rat sarcoma virus oncogene | MALT, mucosa-associated lymphoid tissue | FLICE, FADD-like IL-1β-converting enzyme | FDA, US Food and Drug Administration | βTrCPP, β-transducin repeat-containing proteint | IKK, IκBα kinase | XIAP, X chromosome-linked inhibitor of apoptosis protein | BCL-2, B-cell lymphoma 2 | MAP, mitogen activated protein | TME, tumour microenvironment | cIAP, cellular inhibitor of apoptosis | CLL, chronic lymphocytic leukaemia | SMAC, second mitochondria-derived activator of caspases | BFL-1, Bcl-2-related gene expressed in foetal liver | PTEN, phosphatase and tensin homolog
Journal Article
The EMBO journal, ISSN 1460-2075, 12/2005, Volume 25, Issue 1, pp. 129 - 138
Notch1 specifically upregulates expression of the cytokine interferon‐γ in peripheral T cells through activation of NF‐κB... 
NF‐κB | interferon‐γ | Notch1 | IκBα | NF-κB | Interferon-γ | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | interferon-γ
Journal Article
Inflammation research, ISSN 1023-3830, 2/2019, Volume 68, Issue 2, pp. 147 - 155
... attenuates complete Freund’ s adjuvant-induced arthritis in rats via modulation of MAPKs/NF-κB Hui Lin 1,2 · Zhe Wang 1 · Jinmei Shen 1 · Junmei Xu 1 · Hui Li 1 Received... 
Allergology | Neurology | NF-κB | Biomedicine | Immunology | Dermatology | Rheumatology | Pro-inflammatory cytokines | Arthritis | Inflammation | Pharmacology/Toxicology | IκBα | Arthritis, Experimental - drug therapy | Excitatory Amino Acid Antagonists - therapeutic use | Phosphorylation | Apoptosis - drug effects | Male | Ketamine - administration & dosage | Arthritis, Experimental - pathology | Arthritis, Experimental - chemically induced | Ketamine - therapeutic use | Cytokines - blood | Excitatory Amino Acid Antagonists - administration & dosage | Rats | Joints - pathology | Edema - drug therapy | I-kappa B Proteins - drug effects | Rats, Sprague-Dawley | Foot | Administration, Intravenous | Freund's Adjuvant - administration & dosage | Animals | Signal Transduction - drug effects | Cytokines - antagonists & inhibitors | Edema - pathology | Mitogen-Activated Protein Kinases - drug effects | NF-kappa B - drug effects | Cytochrome | Intravenous administration | Bax protein | Caspase-3 | Interleukin 6 | Proteins | Signal transduction | Mitochondria | Translocation | NF-κB protein | Swelling | Cytokines | Caspase | Chemiluminescence | Tumor necrosis factor-α | IL-1β | Joint diseases | Nuclear transport | Cytochrome c | Organic chemistry | Ketamine | Rheumatoid arthritis | Cytochromes | Apoptosis | Index Medicus
Journal Article
Journal Article
Journal Article
The EMBO Journal, ISSN 0261-4189, 12/2002, Volume 21, Issue 23, pp. 6539 - 6548
The nuclear function of the heterodimeric NF‐κB transcription factor is regulated in part through reversible acetylation of its RelA subunit... 
acetylation | p300 | deacetylation | RelA | IκBα | Acetylation | Deacetylation
Journal Article