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Gut, ISSN 0017-5749, 02/2016, Volume 65, Issue 2, pp. 225 - 237
Journal Article
Gut, ISSN 0017-5749, 06/2018, Volume 67, Issue 6, pp. 1052 - 1063
BackgroundNeutrophils are accumulated in inflamed mucosa of IBD and play an important role in the pathogenesis. CD177 is expressed in neutrophils specifically... 
INTERLEUKINS | CELLULAR IMMUNOLOGY | MUCOSAL IMMUNOLOGY | IBD BASIC RESEARCH | INTESTINAL INFLAMMATION | BACTERIAL PATHOGENS | INFLAMMATORY-BOWEL-DISEASE | IMMUNE CELLS | EXPERIMENTAL COLITIS | CROHNS-DISEASE | ULCERATIVE-COLITIS | CYTOKINE | GASTROENTEROLOGY & HEPATOLOGY | IL-22 | T-CELLS | Index Medicus | Abridged Index Medicus
Journal Article
Gut, ISSN 0017-5749, 08/2012, Volume 61, Issue 8, pp. 1146 - 1153
ObjectivesLoss of intestinal barrier function plays an important role in the pathogenesis of inflammatory bowel disease (IBD). Shedding of intestinal... 
CROHNS-DISEASE | RELATIVES | EPITHELIAL GAPS | JEJUNAL MUCOSA | SMALL-INTESTINAL PERMEABILITY | ULCERATIVE-COLITIS | IN-VIVO | MOUSE | FLUID TRANSPORT | GASTROENTEROLOGY & HEPATOLOGY | TIGHT | Fluorescent Dyes - pharmacokinetics | Predictive Value of Tests | Recurrence | Intestinal Mucosa - metabolism | Prognosis | Prospective Studies | Humans | Middle Aged | Male | Fluorescein - pharmacokinetics | Inflammatory Bowel Diseases - metabolism | Microscopy, Confocal - methods | Disease Progression | Pilot Projects | Inflammatory Bowel Diseases - pathology | Adult | Female | Endoscopy, Gastrointestinal - methods | Intestinal Mucosa - pathology | Inflammatory bowel diseases | Care and treatment | Usage | Epithelial cells | Microscope and microscopy | Physiological aspects | Research | Diagnosis | Health aspects | Inflammatory bowel disease | Small intestine | Rodents | Mucous membrane | Index Medicus | Abridged Index Medicus | IBD basic research | apoptosis | gastrin | cell shedding | ulcerative colitis | Inflammatory Bowel Disease | Confocal laser endomicroscopy | colonoscopy | tight junction | barrier function | mucosal healing | gut differentiation | fluorescein | colorectal cancer | Barrett's metaplasia | cell death | IBD models | endoscopy | colorectal metastases | gastrointestinal physiology | Crohn's Disease | Barrett's oesophagus | magnifying colonoscopy | tumour necrosis factor | 1506
Journal Article
Gut, ISSN 0017-5749, 08/2015, Volume 64, Issue 8, pp. 1236 - 1247
Journal Article
Gut, ISSN 0017-5749, 01/2014, Volume 63, Issue 1, pp. 116 - 124
Objective Western diet is a risk factor for Crohn's disease (CD). Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) is abnormally expressed... 
CROHNS-DISEASE | GUT INFLAMMATION | FECAL STREAM | MICROBIOTA | INTESTINAL BARRIER FUNCTION | INVASIVE E. COLI | PATHOGENESIS | DIETARY - GASTROINTESTINAL INFECTIONS | INFLAMMATORY-BOWEL-DISEASE | IBD BASIC RESEARCH | ILEAL MUCOSA | HUMAN GUT | GASTROENTEROLOGY & HEPATOLOGY | INDUCED OBESITY | INTESTINAL PERMEABILITY | Dysbiosis - etiology | Cell Adhesion Molecules - genetics | Intestinal Mucosa - metabolism | Diet, High-Fat - adverse effects | Homeostasis | Dysbiosis - microbiology | Microbiota | Female | Crohn Disease - etiology | Escherichia coli - physiology | Escherichia coli Infections - etiology | Biomarkers - metabolism | Genetic Predisposition to Disease | Cytokines - metabolism | Colon - pathology | Mice, Inbred C57BL | Mice, Transgenic | Intestinal Mucosa - microbiology | Cell Adhesion Molecules - metabolism | Colon - metabolism | Dysbiosis - metabolism | Host-Pathogen Interactions | Animals | Dietary Sucrose - adverse effects | Colon - microbiology | Mice | Dysbiosis - pathology | Intestinal Mucosa - pathology | Crohn's disease | Research | High-carbohydrate diet | Health aspects | Escherichia coli | Risk factors | Antigens | Pathogens | Cytokines | Laboratories | Inflammation | Permeability | Gene expression | Small intestine | Investigations | Crohns disease | Inflammatory bowel disease | Diet | E coli | Rodents | Bacteria | Tumor necrosis factor-TNF | Metabolic disorders | Index Medicus | Abridged Index Medicus | Life Sciences | Microbiology and Parasitology | Immunology | Biochemistry, Molecular Biology | Genomics | Food and Nutrition | Innate immunity | Cellular Biology | Molecular biology | Bacteriology | Cell Behavior
Journal Article
Gut, ISSN 0017-5749, 04/2016, Volume 65, Issue 4, pp. 584 - 594
Journal Article
Journal Article
Gut, ISSN 0017-5749, 01/2012, Volume 61, Issue 1, pp. 78 - 85
Objective Mesenteric fat hyperplasia is a hallmark of Crohn's disease (CD), and C reactive protein (CRP) is correlated with disease activity. The authors... 
INFLAMMATORY-BOWEL-DISEASE | ADIPONECTIN | TOLL-LIKE RECEPTOR | ENDOSCOPIC SEVERITY | PREADIPOCYTES | INTERLEUKIN-6 | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | ADIPOSE-TISSUE | HUMAN ADIPOCYTES | INNATE IMMUNITY | Mesentery - metabolism | Tumor Necrosis Factor-alpha - metabolism | Prospective Studies | Abdominal Fat - microbiology | Humans | Crohn Disease - metabolism | Lipopolysaccharides - metabolism | Male | C-Reactive Protein - metabolism | Escherichia coli - metabolism | Adult | Crohn Disease - microbiology | Female | Ileitis - metabolism | Escherichia coli - physiology | Interleukin-6 - metabolism | Cell Line | Mesentery - microbiology | Colitis, Ulcerative - metabolism | Bacterial Translocation | Abdominal Fat - metabolism | Animals | Colitis, Ulcerative - microbiology | Ileitis - microbiology | Mice | Lymph Nodes - microbiology | Adipose tissues | C-reactive protein | Causes of | Development and progression | Crohn's disease | Genetic aspects | Research | Gene expression | Health aspects | Lymphatic system | Cytokines | Biosynthesis | Inflammation | Adipocytes | Crohns disease | Streptococcus infections | Proteins | Studies | Inflammatory bowel disease | Body mass index | Genotype & phenotype | Biopsy | Rodents | Surgery | Bacteria | Tumor necrosis factor-TNF | Gram-negative bacteria | Index Medicus | Abridged Index Medicus | IBD basic research | antibiotic therapy | bacterial adherence | 2,4,6-trinitrobenzene sulfonic acid | TNF-alpha | IBD clinical | IBD | bacterial overgrowth | anti-bacterial peptide | Helicobacter pylori | acute hepatitis | bacterial translocation | antibiotics: clinical trials | ulcerative colitis | cytokines | Inflammatory Bowel Disease | gut inflammation | mucosal immunology | IBD models | bacteraemia | azathioprine | anti-bacterial mucosal immunity | bacterial infection | genetic polymorphisms | C Reactive protein | thiopurine methyltransferase | alcoholic liver disease | antibacterial peptide | cell biology | 6-mercaptopurine | mesenteric fat | non-ulcer dyspepsia | small intestine | bacterial pathogenesis | gastric neoplasia | 1506 | non-alcoholic steatohepatitis
Journal Article
Gut, ISSN 0017-5749, 08/2013, Volume 62, Issue 8, pp. 1122 - 1130
Objective Etrolizumab (rhuMAb β7, anti-β7, PRO145223) is a humanised monoclonal antibody targeting the β7 subunit of the heterodimeric integrins α4β7 and αEβ7,... 
IBD basic research | IBD clinical | Etrolizumab | apoptosis | IBD | MONOCLONAL-ANTIBODY | antibody targeted therapy | HUMANIZED ANTIBODY | CELL-ADHESION MOLECULE-1 | integrins | dendritic cells | genetics | safety | rhuMAb 7 | pharmacokinetics | inflammatory bowel disorders | LAMINA PROPRIA LYMPHOCYTES | ulcerative colitis | cytokines | immunology | T-CELLS | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | CROHNS-DISEASE | cell cycle | signal transduction | IBD models | drug development | Crohn's disease | E-CADHERIN | IBD-genetics | autoimmune disease | INFLAMMATORY-BOWEL-DISEASE | arthritis | CD103(+) DENDRITIC CELLS | GASTROENTEROLOGY & HEPATOLOGY | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Gastrointestinal Agents - administration & dosage | Antibodies, Monoclonal - therapeutic use | Male | Antibodies, Monoclonal - blood | Dose-Response Relationship, Drug | Young Adult | Antibodies, Monoclonal, Humanized | Injections, Subcutaneous | Adult | Female | Colitis, Ulcerative - drug therapy | Severity of Illness Index | Double-Blind Method | Treatment Outcome | Colitis, Ulcerative - blood | Antibodies, Monoclonal - administration & dosage | Adolescent | Gastrointestinal Agents - therapeutic use | Aged | Gastrointestinal Agents - adverse effects | Gastrointestinal Agents - blood | Infusions, Intravenous | Headache | Immunoglobulins | Intravenous administration | Wound healing | Dendritic cells | Migration | Inflammation | Injection | Retention | Crohns disease | Cell adhesion & migration | Inflammatory bowel disease | Studies | Lymphocytes | Monoclonal antibodies | Remission | Pharmacokinetics | Chronic illnesses | Ulcerative colitis | Integrins | Index Medicus | Abridged Index Medicus | rhuMAb β7 | Inflammatory Bowel Disease | IBD–genetics | 1506
Journal Article