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icariin (842) 842
index medicus (397) 397
animals (290) 290
flavonoids - pharmacology (243) 243
pharmacology & pharmacy (203) 203
rats (189) 189
male (156) 156
expression (143) 143
mice (137) 137
in-vitro (130) 130
flavonoids (128) 128
apoptosis (126) 126
humans (116) 116
rats, sprague-dawley (100) 100
differentiation (99) 99
cells (97) 97
osteoporosis (95) 95
medicine, research & experimental (90) 90
biochemistry & molecular biology (84) 84
female (79) 79
chemistry, medicinal (74) 74
oxidative stress (74) 74
analysis (73) 73
epimedium - chemistry (72) 72
proliferation (67) 67
drugs, chinese herbal - pharmacology (65) 65
inflammation (64) 64
osteogenic differentiation (64) 64
activation (63) 63
gene expression (62) 62
flavonoids - therapeutic use (61) 61
proteins (60) 60
health aspects (59) 59
epimedium (57) 57
cell proliferation - drug effects (55) 55
inhibition (55) 55
cell biology (54) 54
cells, cultured (53) 53
plant sciences (53) 53
chemistry, analytical (50) 50
flavonoids - chemistry (50) 50
cell differentiation - drug effects (49) 49
integrative & complementary medicine (49) 49
apoptosis - drug effects (48) 48
oncology (48) 48
rodents (45) 45
signal transduction - drug effects (45) 45
stem cells (45) 45
cell line (44) 44
flavones (44) 44
care and treatment (43) 43
chemistry, multidisciplinary (43) 43
disease models, animal (43) 43
research (43) 43
bioflavonoids (42) 42
pathway (42) 42
dose-response relationship, drug (38) 38
model (37) 37
alzheimer's disease (36) 36
glycosides (36) 36
mesenchymal stem-cells (36) 36
neurosciences (36) 36
osteogenesis - drug effects (36) 36
herba epimedii (35) 35
kinases (35) 35
estrogen (34) 34
nf-kappa-b (34) 34
flavonoids - administration & dosage (33) 33
signal transduction (33) 33
studies (33) 33
tissue engineering (33) 33
cell line, tumor (31) 31
icaritin (31) 31
cell proliferation (30) 30
extract (30) 30
icariside ii (30) 30
postmenopausal women (30) 30
cell survival - drug effects (29) 29
growth (29) 29
isoflavones (29) 29
rats, wistar (29) 29
gene-expression (28) 28
alzheimers-disease (27) 27
biochemical research methods (27) 27
bone loss (27) 27
cancer (27) 27
disease (27) 27
osteoblasts (27) 27
pharmacology (27) 27
plant extracts - pharmacology (27) 27
regeneration (27) 27
biotechnology (26) 26
chemistry (26) 26
collagen (26) 26
flavonoids - isolation & purification (26) 26
marrow stromal cells (26) 26
physiological aspects (26) 26
biocompatibility (25) 25
biology (25) 25
bone (25) 25
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Planta Medica, ISSN 0032-0943, 08/2008, Volume 74, Issue 9
The pharmacological treatment of erectile dysfunction relies mostly on the use of sildenafil (Viagra®) and other sildenafil-type selective inhibitors of... 
Conference Proceeding
Journal of Pharmaceutical and Biomedical Analysis, ISSN 0731-7085, 02/2018, Volume 149, pp. 525 - 531
[Display omitted] •The reason of icariin increase in Herba Epimedii by heating is demonstrated.•The increased icariin was from CQICA via deglycosylation.•The... 
3′′′-carbonyl-2′′-β-l-quinovosyl icariin | Icariin | Herba Epimedii | Heating process | Conversion | 3′′′-carbonyl-2′′-β-L-quinovosyl icariin | CHEMISTRY, ANALYTICAL | EXTRACTION | MECHANISM | Icarlin | 3 '''-carbonyl-2 ''-beta-L-quinovosyl icariin | PHARMACOLOGY & PHARMACY | FLAVONOL GLYCOSIDES | Flavonoids | Flavones | Bioflavonoids | Analysis
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2018, Volume 16, Issue 3, pp. 452 - 458
Epimedium is used in traditional Chinese medicine and contains flavonol glycosides that exhibit multiple biological activities. These bioactive flavonol... 
CHEMISTRY, ORGANIC | CELLS | ARABIDOPSIS-THALIANA | ICARIIN | BIOSYNTHESIS
Journal Article
The FASEB Journal, ISSN 0892-6638, 01/2020, Volume 34, Issue 1, pp. 1783 - 1801
The natural product icariin (ICA) and its phosphorylated derivatives (pICA) have been shown to have outstanding anti‐inflammatory and antioxidant properties.... 
icariin | enterotoxigenic Escherichia coli K88 | phosphorylated icariin | intestinal barrier function | p38 MAPK | CELLS | OXIDATIVE STRESS | PROTECTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ZINC-OXIDE | TIGHT JUNCTION DISRUPTION | K88 | WEANED PIGS | CELL BIOLOGY | SUPPLEMENTATION | PIGLETS | BIOLOGY | INFLAMMATORY RESPONSE
Journal Article
Chinese Journal of Cardiology, ISSN 0253-3758, 08/2016, Volume 44, Issue 8, pp. 707 - 713
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 12/2011, Volume 138, Issue 3, pp. 731 - 736
Ethnopharmacological relevance: Icariin is a major constituent of flavonoid isolated from the plant Herba epimedii, which is used as a traditional Chinese... 
Icariin | Collagen IV | Transforming growth factor-β | Diabetic nephropathy
Journal Article
Phytomedicine, ISSN 0944-7113, 01/2011, Volume 18, Issue 2-3, pp. 176 - 185
Icariin has been reported to enhance bone healing and treat osteoporosis. In this study, we examined the detail molecular mechanisms of icariin on... 
Icariin | NF-κB | Epimedium pubescens | Osteoclast | HIF-1α | Gene expression | LPS | MAPKs
Journal Article
Molecular Medicine Reports, ISSN 1791-2997, 09/2018, Volume 18, Issue 3, pp. 3445 - 3450
Journal Article
Yiyong Shengwu Lixue/Journal of Medical Biomechanics, ISSN 1004-7220, 08/2017, Volume 32, Issue 4, pp. 325 - 330
Journal Article
Yaoxue Xuebao, ISSN 0513-4870, 07/2018, Volume 53, Issue 7, pp. 1100 - 1106
Journal Article
The American Journal of Sports Medicine, ISSN 0363-5465, 7/2019, Volume 47, Issue 8, pp. 1964 - 1974
Background: Tendon-bone interface (TBI) injuries are common in sports activities. Owing to the limited regenerative ability of the TBI, its functional healing... 
icariin | partial patellectomy | tendon-bone healing | platelet-rich plasma | tendon-bone interface
Journal Article
by Feng, KP and Chen, RD and Xie, KB and Chen, DW and Liu, JM and Du, WY and Yang, L and Dai, JG
ORGANIC & BIOMOLECULAR CHEMISTRY, ISSN 1477-0520, 09/2019, Volume 17, Issue 35, pp. 8106 - 8114
Icariin (1a), a 7-O-glycosylated flavonoid glycoside, is recognized as the major pharmacologically active ingredient of Epimedium plants, which have been used... 
GLYCOSIDES | CHEMISTRY, ORGANIC | CELLS | OSTEOGENIC DIFFERENTIATION | OXIDATIVE STRESS | ICARIIN
Journal Article
Yiyong Shengwu Lixue/Journal of Medical Biomechanics, ISSN 1004-7220, 10/2016, Volume 31, Issue 5, pp. 456 - 466
Journal Article
BioTechnology: An Indian Journal, ISSN 0974-7435, 11/2014, Volume 10, Issue 9, pp. 4151 - 4155
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2010, Volume 642, Issue 1, pp. 146 - 153
This study aimed to investigate the mechanism underlying the attenuation of LPS-induced lung inflammation by icariin in vivo and in vitro. The... 
Icariin | NF-κB p65 | RAW 264.7 macrophages cells | Phosphatidylinositol 3-kinase/amino kinase terminal (PI3K/Akt) | ACTIVATION | MECHANISM | PHOSPHORYLATION | ENDOTOXIN | ACUTE LUNG INJURY | AKT | NF-kappa B p65 | RESPIRATORY-DISTRESS-SYNDROME | TOLL-LIKE RECEPTOR-2 | 3-KINASE PATHWAY | ANIMAL-MODELS | PHARMACOLOGY & PHARMACY
Journal Article
생약학회지, ISSN 0253-3073, 2019, Volume 50, Issue 4, p. 312
In order to obtain basic data on the shelf life of Epimedii Herba (EH), a physicochemical characteristics including weight loss rate, loss on drying, ash,... 
Icariin | Packaging method | Epimedii Herba | Storage period
Journal Article
International Journal of Biological Macromolecules, ISSN 0141-8130, 10/2019, Volume 139, pp. 1063 - 1073
Achyranthes bidentata has been traditionally used in China as a nature remedy for osteoporosis; however, little is known about the osteoprotective effects of... 
Achyranthes bidentata | Osteoporosis | Polysaccharides | POLYMER SCIENCE | ICARIIN | BLUME | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, APPLIED | ROOT EXTRACT
Journal Article
Yaoxue Xuebao, ISSN 0513-4870, 12/2015, Volume 50, Issue 12, pp. 1652 - 1659
Journal Article
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