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Haematologica (Roma), ISSN 1592-8721, 05/2010, Volume 95, Issue 10, pp. 1668 - 1674
Journal Article
Pharmacology & therapeutics (Oxford), ISSN 0163-7258, 08/2015, Volume 152, pp. 54 - 62
Journal Article
Nature (London), ISSN 1476-4687, 06/2018, Volume 559, Issue 7712, pp. 125 - 129
Somatic mutations in the isocitrate dehydrogenase 2 gene (IDH2) contribute to the pathogenesis of acute myeloid leukaemia (AML... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Triazines - therapeutic use | Humans | Glutarates - blood | Isocitrate Dehydrogenase - antagonists & inhibitors | Aminopyridines - chemistry | Aminopyridines - therapeutic use | Enzyme Inhibitors - chemistry | HEK293 Cells | Protein Multimerization - genetics | Leukemia, Myeloid, Acute - drug therapy | Female | Triazines - chemistry | Mutant Proteins - antagonists & inhibitors | Allosteric Site - genetics | Triazines - pharmacology | Allosteric Site - drug effects | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Mutant Proteins - genetics | Models, Molecular | Isocitrate Dehydrogenase - genetics | Leukemia, Myeloid, Acute - blood | Enzyme Inhibitors - therapeutic use | Disease Progression | Isoleucine - genetics | Drug Resistance, Neoplasm - genetics | Animals | Aminopyridines - pharmacology | Alleles | Glutamine - genetics | Glutarates - metabolism | Mice | Mutation | Clinical Trials, Phase I as Topic | Clinical Trials, Phase II as Topic | Drug Resistance, Neoplasm - drug effects | Leukemia, Myeloid, Acute - genetics | Antimitotic agents | Pharmaceutical research | Research | Drug resistance | Antineoplastic agents | Glutamine | Plasma | Pathogenesis | Leukemia | Lung cancer | Cloning | Neutrophils | Kinases | Cancer therapies | Patients | Proteins | Disease resistance | Allosteric properties | Inhibitors | Bone marrow | Dimers | Inhibition | Target acquisition | Isocitrate dehydrogenase | Isoleucine | Neutropenia | Index Medicus | AG-120 | cancer metabolism | leukemia | AG-221 | metabolite | enasidenib | epigenetic | IDH1 | IDH2 | glioma | ivosidenib
Journal Article
Oncotarget, ISSN 1949-2553, 08/2012, Volume 3, Issue 7, pp. 709 - 722
Journal Article
Journal Article