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Journal of Neuroscience, ISSN 0270-6474, 04/2003, Volume 23, Issue 7, pp. 2549 - 2556
Synaptic responses of interneurons in the rat lateral amygdala (LA) to electrical microstimulation of putative cortical and thalamic afferents were studied in... 
ifenprodil
Journal Article
Trends in Pharmacological Sciences, ISSN 0165-6147, 12/2001, Volume 22, Issue 12, pp. 636 - 642
Ifenprodil and a group of related compounds are selective antagonists of NR2B-containing NMDA receptors. These compounds are antinociceptive in a variety of... 
Ifenprodil
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 09/2001, Volume 21, Issue 17, pp. 6889 - 6896
The lateral nucleus of the amygdala (LA) is an essential component of the neural circuitry underlying Pavlovian fear conditioning. Although blockade of NMDA... 
ifenprodil
Journal Article
Neuropharmacology, ISSN 0028-3908, 01/2001, Volume 40, Issue 2, pp. 212 - 220
The N-methyl-D-aspartate (NMDA) antagonist ifenprodil and several structurally related compounds are highly selective for the NR2B-containing receptor subtype.... 
ifenprodil
Journal Article
Neuropharmacology, ISSN 0028-3908, 2011, Volume 61, Issue 7, pp. 1172 - 1181
Studies have shown that anabolic androgenic steroids (AASs) can induce profound changes to mental health. Commonly reported psychiatric side effects among AAS... 
(+)-SKF 10,047 | Neurosteroids | Anabolic androgenic steroids (AAS) | NMDA ( N-methyl- d-aspartyl) receptor | Nandrolone | Sigma receptor | Pregnenolone sulphate (PS) | Pregnanolone sulphate (3α5βS) | NR2B subunit | [ 3H]ifenprodil | Rat brain | H]ifenprodil | NMDA (N-methyl-d-aspartyl) receptor | MALE NORMAL VOLUNTEERS | DEHYDROEPIANDROSTERONE-SULFATE | NR28 subunit | [H-3]ifenprodil | FORCED SWIMMING TEST | GUINEA-PIG BRAIN | NEUROSCIENCES | MALE-RAT BRAIN | NEUROACTIVE STEROIDS | PHARMACOLOGY & PHARMACY | NMDA (N-methyl-D-aspartyl) receptor | CENTRAL-NERVOUS-SYSTEM | Pregnanolone sulphate (3 alpha 5 beta S) | H-3 IFENPRODIL | BINDING-SITES | METHYL-D-ASPARTATE | Frontal Lobe - metabolism | Receptors, N-Methyl-D-Aspartate - metabolism | Dehydroepiandrosterone Sulfate - metabolism | Male | Pregnanolone - metabolism | Pregnenolone - metabolism | Anabolic Agents - pharmacology | Neurons - metabolism | Androgens - adverse effects | Nandrolone - adverse effects | Neurons - drug effects | Pregnanolone - analogs & derivatives | Receptors, sigma - metabolism | Allosteric Regulation - drug effects | Nandrolone - administration & dosage | Anabolic Agents - adverse effects | Nandrolone - analogs & derivatives | Neurotransmitter Agents - metabolism | Rats | Random Allocation | Androgens - administration & dosage | Rats, Sprague-Dawley | Nerve Tissue Proteins - metabolism | Animals | Anabolic Agents - administration & dosage | Androgens - pharmacology | Nandrolone - pharmacology | Frontal Lobe - drug effects | Kinetics | Anabolic steroids | Methyl aspartate | Dehydroepiandrosterone | Cognition disorders | Progesterone | Depression, Mental | Medical and Health Sciences | Medicin och hälsovetenskap | [H]ifenprodil | 047 | (+)-SKF 10
Journal Article
Neuropharmacology, ISSN 0028-3908, 04/2000, Volume 39, Issue 6, pp. 943 - 951
Hippocampal CA3 pyramidal neurons receive synaptic inputs from commissural and associational fibers on both apical and basal dendrites. NMDA receptors at these... 
ifenprodil
Journal Article
Analytical Chemistry, ISSN 0003-2700, 08/2018, Volume 90, Issue 15, pp. 9347 - 9352
In this study, we developed a two-photon fluorescent probe for detection of peroxynitrite (ONOO–) near the N-methyl-d-aspartate (NMDA) receptor. This... 
CHEMISTRY, ANALYTICAL | SUPEROXIDE | PEROXYNITRITE | DISEASE | NITRIC-OXIDE | IFENPRODIL | GENERATION | SELECTIVE DETECTION | ANTAGONISTS | LIVING CELLS
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 11/2011, Volume 119, Issue 4, pp. 686 - 696
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 08/2019, Volume 27, Issue 16, pp. 3559 - 3567
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 11/2019, Volume 62, Issue 21, pp. 9450 - 9470
Aspiring to develop a positron emission tomography (PET) imaging agent for the GluN2B subunits of the N-methyl-D-aspartate receptor (NMDAR), a key therapeutic... 
NR2B | DESIGN | POTENT | CHEMISTRY, MEDICINAL | ANTAGONIST | CP-101,606 | NMDA RECEPTORS | BIOLOGICAL EVALUATION | IFENPRODIL | PHARMACOLOGICAL EVALUATION | BINDING
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 12/2019, Volume 108, Issue 12, pp. 3823 - 3830
Although N-methyl- -aspartate receptor antagonists are hopeful therapeutic agents against cerebral ischemia/reperfusion (I/R) injury, effective approaches are... 
cerebral ischemia/reperfusion injury | blood-brain barrier | N-methyl-d-aspartate receptors | ifenprodil | liposomes | middle cerebral artery occlusion
Journal Article
Diabetes and Metabolism Journal (DMJ), ISSN 2233-6079, 2019, Volume 43, Issue 2, p. 222
Background: This study investigated the role of NR2B in a modulated pain process in the painful diabetic neuropathy (PDN) rat using various pain... 
Diabetic neuropathies | Ifenprodil | NR2B NMDA receptor | Pain measurement | Hyperalgesia
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 08/2019, Volume 60, Issue 8, pp. 1167 - 1173
The study aims to investigate the performance characteristics of the enantiomers of C-11-Me-NB1, a recently reported PET imaging probe that targets the GluN2B... 
NMDA RECEPTOR | CP-101,606 | ANTAGONIST | PET imaging | sigma-receptor | receptor occupancy | neurodegeneration | IFENPRODIL | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | GluN2B | MOLECULAR-MECHANISMS
Journal Article
Journal Article
Nature, ISSN 0028-0836, 07/2011, Volume 475, Issue 7355, pp. 249 - 253
Journal Article
Experimental Neurology, ISSN 0014-4886, 03/2018, Volume 301, pp. 13 - 25
Excessive glutamate in cerebrospinal fluid after subarachnoid hemorrhage (SAH) causes excitotoxic damage through calcium overloading and a subsequent apoptotic... 
Ca2 + overloading | Ifenprodil | Subarachnoid hemorrhage | JNJ16259685 | Glutamate excitotoxicity | overloading | ACTIVATION | ANTAGONIST | STIMULATION | VASOSPASM | POSITIVE FEEDBACK | MECHANISMS | Ca2+ overloading | NEUROSCIENCES | EXCITOTOXICITY | INTRACEREBRAL HEMORRHAGE | EARLY BRAIN-INJURY | EXPRESSION
Journal Article
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