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index medicus (668) 668
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interferon-induced helicase, ifih1 (485) 485
animals (282) 282
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rig-i (254) 254
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melanoma (95) 95
genetic aspects (91) 91
interferon-induced helicase, ifih1 - immunology (91) 91
proteins (89) 89
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dermatomyositis - immunology (88) 88
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article (82) 82
gene expression (82) 82
cells, cultured (81) 81
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health aspects (80) 80
research (77) 77
autoantibodies (74) 74
interferon-induced helicase, ifih1 - genetics (74) 74
rheumatology (72) 72
abridged index medicus (70) 70
biological response modifiers (70) 70
antiviral responses (67) 67
expression (67) 67
interferon-induced helicase, ifih1 - metabolism (67) 67
toll-like receptors (65) 65
genes (64) 64
poly i-c - pharmacology (64) 64
adapter protein (63) 63
autoantibodies - blood (63) 63
mice, knockout (63) 63
rna, double-stranded - metabolism (63) 63
autoimmunity (62) 62
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research article (62) 62
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dermatomyositis - complications (59) 59
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toll-like receptor 3 - metabolism (57) 57
infections (55) 55
interferon-beta - genetics (55) 55
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diabetes mellitus, type 1 - genetics (49) 49
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Journal Article
Molecular Cell, ISSN 1097-2765, 05/2016, Volume 62, Issue 4, pp. 586 - 602
RIG-I and MDA5 sense virus-derived short 5′ppp blunt-ended or long dsRNA, respectively, causing interferon production. Non-signaling LGP2 appears to positively... 
ASSEMBLES | RNA HELICASE LGP2 | DETERMINANTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | FILAMENT | CHICKEN | RIG-I | SIGNAL-ACTIVATION | INNATE IMMUNE SENSOR | PARAMYXOVIRUS V PROTEINS | INSIGHTS | CELL BIOLOGY | Interferon-Induced Helicase, IFIH1 - chemistry | RNA-Binding Proteins - genetics | DEAD Box Protein 58 - metabolism | Interferon-Induced Helicase, IFIH1 - genetics | Humans | Structure-Activity Relationship | Avian Proteins - chemistry | Receptors, Pattern Recognition - metabolism | Transfection | DEAD Box Protein 58 - genetics | Adenosine Triphosphate - metabolism | Protein Interaction Domains and Motifs | RNA, Double-Stranded - metabolism | Nucleic Acid Conformation | Binding Sites | RNA, Double-Stranded - chemistry | Cell Line | DEAD Box Protein 58 - chemistry | Avian Proteins - metabolism | Receptors, Pattern Recognition - chemistry | RNA-Binding Proteins - chemistry | Adenosine Triphosphatases - metabolism | Interferon-Induced Helicase, IFIH1 - metabolism | Models, Molecular | Hydrolysis | Animals | Chickens | RNA, Double-Stranded - genetics | Protein Binding | Receptors, Pattern Recognition - genetics | Adenosine Triphosphatases - chemistry | Adenosine Triphosphatases - genetics | Adenosine Diphosphate - metabolism | RNA-Binding Proteins - metabolism | Avian Proteins - genetics | Oligomers | RNA | Crystals | Interferon | Structure | Biological response modifiers | Molecular biology | Index Medicus | Life Sciences | Immunology
Journal Article
eLife, ISSN 2050-084X, 03/2016, Volume 5, Issue 2016, pp. e11275 - e11275
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 07/2017, Volume 214, Issue 7, pp. 1949 - 1972
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2016, Volume 11, Issue 4, pp. e0154285 - e0154285
Objective Autoantibodies to melanoma differentiation-associated gene 5 (MDA5) are specifically expressed in patients with dermatomyositis (DM) and are... 
INTERSTITIAL LUNG-DISEASE | AMYOPATHIC DERMATOMYOSITIS | ANTI-MDA5 | MULTIDISCIPLINARY SCIENCES | CADM-140 | AUTOANTIGEN | SPECTRUM | JAPANESE PATIENTS | ANTI-CADM-140 ANTIBODY | CLASSIFICATION CRITERIA | MYOSITIS | Interferon-Induced Helicase, IFIH1 - genetics | Immunoprecipitation | Dermatomyositis - blood | Autoantibodies - blood | Humans | Middle Aged | Idiopathic Interstitial Pneumonias - diagnosis | Idiopathic Interstitial Pneumonias - blood | Male | Case-Control Studies | Enzyme-Linked Immunosorbent Assay - standards | Dermatomyositis - immunology | Interferon-Induced Helicase, IFIH1 - antagonists & inhibitors | Sensitivity and Specificity | Polymyositis - diagnosis | Adult | Female | Polymyositis - immunology | Diagnosis, Differential | Gene Expression | Connective Tissue Diseases - diagnosis | Dermatomyositis - diagnosis | Interferon-Induced Helicase, IFIH1 - immunology | Connective Tissue Diseases - immunology | Polymyositis - blood | Aged | Connective Tissue Diseases - blood | Idiopathic Interstitial Pneumonias - immunology | Care and treatment | Autoantibodies | Health aspects | Enzyme-linked immunosorbent assay | Methods | Dermatomyositis | Pneumonia | Laboratories | Lung | Antibodies | Arthritis | Assaying | Proteins | Connective tissues | Immunology | Classification | Scleroderma | Lupus | Antigens | Enzymes | Immunoglobulins | Sensitivity analysis | Internal medicine | Dermatology | Lung diseases | Melanoma | Rheumatology | Disease control | Patients | Fever | Medicine | Medical centres | Polymyositis | Medical prognosis | Differentiation | Index Medicus
Journal Article
Journal of Virology, ISSN 0022-538X, 06/2017, Volume 91, Issue 11
Journal Article
Journal Article
CANCER SCIENCE, ISSN 1349-7006, 01/2018, Volume 109, pp. 977 - 977
Conference Proceeding
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 50, pp. 20472 - 20480
Self/non-self-discrimination by the innate immune system relies on germline-encoded, non-rearranging receptors expressed by innate immune cells recognizing... 
cellular immune response | dsRNA | PATHWAYS | CELLS | HELICASE LGP2 | BIOCHEMISTRY & MOLECULAR BIOLOGY | double-stranded RNA (dsRNA) | HUMAN CYTOMEGALOVIRUS | RIG-I | PARAMYXOVIRUS V-PROTEINS | VIRULENCE | virus | non-self-discrimination | virus infection | NATURAL CYTOTOXICITY RECEPTORS | NKG2D | NKG2D ligands | self | HUMAN FIBROBLASTS | TARGETS | natural killer cells (NK cells) | pattern recognition receptor (PRR) | Interferon-Induced Helicase, IFIH1 - chemistry | RNA-Binding Proteins - genetics | DEAD Box Protein 58 - metabolism | Interferon-Induced Helicase, IFIH1 - genetics | Lentivirus - immunology | Humans | Lentivirus - physiology | Viral Proteins - metabolism | NK Cell Lectin-Like Receptor Subfamily K - metabolism | DEAD Box Protein 58 - genetics | Killer Cells, Natural - immunology | RNA, Viral - metabolism | Genes, Reporter | RNA - metabolism | Recombinant Proteins - metabolism | Cell Line | DEAD Box Protein 58 - chemistry | Cricetinae | Killer Cells, Natural - virology | Cells, Cultured | Gene Expression Regulation | Interferon-Induced Helicase, IFIH1 - metabolism | Viral Proteins - genetics | Immunity, Innate | NK Cell Lectin-Like Receptor Subfamily K - genetics | Animals | NK Cell Lectin-Like Receptor Subfamily K - agonists | Gene Expression Regulation, Viral | Ligands | Killer Cells, Natural - metabolism | Mutation | RNA-Binding Proteins - metabolism | Amino Acid Substitution | Index Medicus | Immunology
Journal Article
Fish and Shellfish Immunology, ISSN 1050-4648, 08/2016, Volume 55, pp. 535 - 549
Journal Article
Journal Article