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Journal Article
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 03/2012, Volume 11, Issue 3, pp. 649 - 659
Previously, we reported that a predominant action of a type-1 insulin-like growth factor receptor (IGF-1R)targeted antibody was through inhibiting... 
CANCER-CELL-MIGRATION | EWINGS-SARCOMA | INSULIN-RECEPTOR | SOLID TUMORS | ADULT BRAIN | ONCOLOGY | HUMAN RHABDOMYOSARCOMA | MONOCLONAL-ANTIBODY | ANTITUMOR-ACTIVITY | EXPRESSION | GROWTH-FACTOR-I | Angiogenesis Inhibitors - immunology | Neovascularization, Physiologic - drug effects | Receptor, IGF Type 1 - metabolism | Receptor, IGF Type 1 - antagonists & inhibitors | Human Umbilical Vein Endothelial Cells - metabolism | Blood Vessels - metabolism | Humans | Molecular Sequence Data | Immunoblotting | Sarcoma - blood supply | Human Umbilical Vein Endothelial Cells - physiology | Base Sequence | Insulin-Like Growth Factor II - pharmacology | Female | Neovascularization, Pathologic - prevention & control | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Receptor, Insulin - immunology | Vascular Endothelial Growth Factor A - pharmacology | Antibodies, Monoclonal - immunology | Human Umbilical Vein Endothelial Cells - drug effects | Antibodies, Monoclonal - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Angiogenesis Inhibitors - pharmacology | Mice, SCID | Receptor, Insulin - antagonists & inhibitors | Sarcoma - pathology | Animals | Blood Vessels - drug effects | Receptor, IGF Type 1 - immunology | Cell Line, Tumor | Receptor, Insulin - metabolism | Cell Proliferation - drug effects | Mice | Neovascularization, Pathologic - metabolism | IGF-1R-targeted antibodies | insulin-like growth factors | sarcomas | angiogenesis
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2016, Volume 478, Issue 4, pp. 1575 - 1581
The insulin-like growth factor 1 receptor (IGF-1R) has been suggested to be involved in hepatocyte differentiation. Human hepatocyte cancer cells and stem... 
Hepatocyte | IGF-1R | Differentiation | Cell Line | Cell Lineage | Human Embryonic Stem Cells - metabolism | Receptor, IGF Type 1 - metabolism | Hepatocytes - cytology | Down-Regulation | Human Embryonic Stem Cells - cytology | Humans | Cell Differentiation | Hepatocytes - metabolism | Proteins | Embryonic stem cells | Medical colleges
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 2009, Volume 387, Issue 1, pp. 36 - 41
Journal Article
Frontiers in Endocrinology, ISSN 1664-2392, 2015, Volume 6
IGF-1R expression and activation levels generally cannot be correlated in cancer cells, suggesting that cellular proteins may modulate IGF-1R activity. Strong... 
Resistance | Pdlim2 | Signaling | Phenotype | Igf-1r | Adhesion | Emt | phenotype | BREAST EPITHELIAL-CELLS | signaling | AKT ACTIVATION | adhesion | E-CADHERIN | BETA-CATENIN | EMT | resistance | TO-MESENCHYMAL TRANSITION | PDLIM2 | INSULIN-LIKE-GROWTH | ENDOCRINOLOGY & METABOLISM | DOMAIN-CONTAINING PROTEIN-2 | ANCHORAGE-INDEPENDENT GROWTH | IGF-1R | FACTOR-I RECEPTOR | NF-KAPPA-B | differentiation | Integrins | therapy resistance
Journal Article