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Drug Development Research, ISSN 0272-4391, 05/2013, Volume 74, Issue 3, pp. 173 - 185
Journal Article
中国药理学报:英文版, ISSN 1671-4083, 2012, Volume 33, Issue 6, pp. 728 - 736
Aim: This study was conducted to test the selectivity of DC031050 on cardiac and neuronal potassium channels. Methods: Human ether-a-go-go related gene (hERG),... 
延迟整流钾电流 | 钾离子通道 | 钾通道 | 电压依赖性 | 锥体神经元 | | 药物治疗 | 抗心律失常 | hERG | DC031050 | KCNQ | dofetilide | delayed rectifier potassium current | Kv1.2 | class III antiarrhythmic agent | BIOLOGICAL ASSAY | MYOCARDIAL-INFARCTION | FLUTTER | METHYLSULFONAMIDO PHENYLETHYLAMINE ANALOGS | HIPPOCAMPAL-NEURONS | CHEMISTRY, MULTIDISCIPLINARY | ATRIAL-FIBRILLATION | IN-VIVO | DRUGS | PHARMACOLOGY & PHARMACY | K+ CHANNELS | Potassium - metabolism | Kv1.2 Potassium Channel - antagonists & inhibitors | Pyramidal Cells - metabolism | Anti-Arrhythmia Agents - pharmacology | Humans | Ether-A-Go-Go Potassium Channels - metabolism | Hippocampus - drug effects | KCNQ Potassium Channels - antagonists & inhibitors | Pyramidal Cells - drug effects | CHO Cells | Cricetinae | Gene Expression | Phenethylamines - pharmacology | Sulfonamides - chemistry | Phenethylamines - chemistry | Rats | Anti-Arrhythmia Agents - chemistry | Ether-A-Go-Go Potassium Channels - genetics | Hippocampus - cytology | Sulfonamides - pharmacology | Rats, Sprague-Dawley | Ether-A-Go-Go Potassium Channels - antagonists & inhibitors | Kv1.2 Potassium Channel - genetics | Patch-Clamp Techniques | Animals | KCNQ Potassium Channels - metabolism | Kv1.2 Potassium Channel - metabolism | KCNQ Potassium Channels - genetics | Heart | Neonates | HERG protein | Pyramidal cells | Therapeutic applications | Potassium channels (voltage-gated) | Hippocampus | KCNQ2 protein | Antiarrhythmic agents | Original
Journal Article
Journal Article
Eksperimental'naya i Klinicheskaya Farmakologiya, ISSN 0869-2092, 2016, Volume 79, Issue 11, pp. 26 - 34
Journal Article
KARDIOLOGIYA, ISSN 0022-9040, 2011, Volume 51, Issue 1, pp. 55 - 64
Journal Article
JOURNAL OF GENERAL PHYSIOLOGY, ISSN 0022-1295, 02/2019, Volume 151, Issue 2, pp. 214 - 230
Drug-induced block of the cardiac rapid delayed rectifying potassium current (l(Kr)), carried by the human ether-a-go-gorelated gene (hERG) channel, is the... 
ACTION-POTENTIALS | QT PROLONGATION | DRUG | III ANTIARRHYTHMIC AGENT | TORSADES-DE-POINTES | PHYSIOLOGY | LEFT-VENTRICULAR WALL | POTASSIUM CHANNELS | RECTIFIER K+-CURRENT | CARDIAC MYOCYTES | HEART-FAILURE
Journal Article
Journal Article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, ISSN 0022-3565, 02/2017, Volume 360, Issue 2, pp. 378 - 387
Free intracellular calcium ([Ca2+]i), in addition to being an important second messenger, is a key regulator of many cellular processes including cell membrane... 
ACTION-POTENTIALS | BREAST-CANCER | III ANTIARRHYTHMIC AGENT | SKELETAL-MUSCLE | BETA-ADRENOCEPTOR | MINOXIDIL SULFATE | PHARMACOLOGY & PHARMACY | SARCOPLASMIC-RETICULUM | SULFONYLUREA RECEPTOR 2B | K+ CHANNEL | VASCULAR SMOOTH-MUSCLE
Journal Article
Journal of Cardiovascular Pharmacology, ISSN 0160-2446, 1992, Volume 20, Issue 2, pp. S96 - S105
Journal Article
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