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The lancet oncology, ISSN 1470-2045, 07/2014, Volume 15, Issue 8, pp. 862 - 873
Summary Background Since the 1990s, fluorouracil-based adjuvant chemotherapy has significantly reduced the risk of tumour recurrence in patients with stage III colon cancer... 
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | ras Proteins - genetics | Colonic Neoplasms - genetics | Proto-Oncogene Proteins p21(ras) | Adenocarcinoma - pathology | Colonic Neoplasms - drug therapy | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Diarrhea - chemically induced | Colonic Neoplasms - surgery | Fluorouracil - therapeutic use | Antibodies, Monoclonal, Humanized - administration & dosage | Leucovorin - adverse effects | Fluorouracil - adverse effects | Infusions, Intravenous - adverse effects | Adult | Female | Leucovorin - therapeutic use | Adenocarcinoma - genetics | Chemotherapy, Adjuvant | Cetuximab | Antibodies, Monoclonal, Humanized - adverse effects | Drug Eruptions - etiology | Exons - genetics | Proto-Oncogene Proteins - genetics | Adenocarcinoma - drug therapy | Mucositis - chemically induced | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Colonic Neoplasms - pathology | Intention to Treat Analysis | Aged | Neoplasm Staging | Organoplatinum Compounds - therapeutic use | Organoplatinum Compounds - adverse effects | Adenocarcinoma - surgery | Prevention | Care and treatment | Chemotherapy | Colon cancer | Hospitals | Leucovorin | Product development | Cancer | Index Medicus | Life Sciences
Journal Article
Journal Article
Clinical Colorectal Cancer, ISSN 1533-0028, 2016, Volume 16, Issue 3, pp. e165 - e170
... which patients with stage II or stage III colorectal cancer will develop metastatic disease. Patients and Methods We used a targeted next-generation sequencing approach to analyze the mutational spectra in stage II and III colon cancer patient samples... 
Hematology, Oncology and Palliative Medicine | Gastroenterology and Hepatology | Tumor evolution | Stage III | Biomarker | Sequencing | Stage II | Life Sciences & Biomedicine | Oncology | Science & Technology | Colonic Neoplasms - genetics | DNA Mutational Analysis | Neoplasm Invasiveness - pathology | Colonic Neoplasms - pathology | Humans | Risk Factors | Alleles | Neoplasm Invasiveness - genetics | Complications and side effects | Colon cancer | Gene mutations | Genetic aspects | Research | Metastasis | Risk factors | Index Medicus
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 10/2015, Volume 149, Issue 4, pp. 1006 - 1016.e9
.... In the past 50 years, the mortality rate from colon cancer has changed relatively little, until recently. This emphasizes the need for new therapies based on a greater... 
Gastroenterology and Hepatology | Metastatic | Tumor Progression | Colon Cancer | ROS | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Colonic Neoplasms - genetics | Reactive Oxygen Species - metabolism | Calcium - metabolism | Neoplastic Stem Cells - drug effects | Humans | Middle Aged | Peptides - genetics | Drug Resistance, Neoplasm | Antigens, CD - genetics | Colonic Neoplasms - metabolism | Antigens, CD - metabolism | Adenocarcinoma - metabolism | Peptides - metabolism | Neoplastic Stem Cells - metabolism | RNA Interference | Time Factors | Forkhead Transcription Factors - metabolism | Adenosine Triphosphate - metabolism | Neoplastic Stem Cells - pathology | Transcription, Genetic | Colonic Neoplasms - therapy | Glycoproteins - genetics | Signal Transduction | HCT116 Cells | Oxygen Consumption | Mitochondria - pathology | Adenocarcinoma - secondary | Peroxiredoxin III - genetics | Adenocarcinoma - therapy | Energy Metabolism | Mice, Inbred NOD | Peroxiredoxin III - metabolism | RNAi Therapeutics | Gene Expression Regulation, Neoplastic | Glycoproteins - metabolism | Dose-Response Relationship, Drug | Transfection | Membrane Potential, Mitochondrial | Adult | Female | Adenocarcinoma - genetics | Antineoplastic Agents - pharmacology | Cell Survival | Mitochondria - metabolism | Mitochondria - drug effects | Forkhead Transcription Factors - genetics | Mice, SCID | AC133 Antigen | HT29 Cells | Xenograft Model Antitumor Assays | Animals | Colonic Neoplasms - pathology | Aged | Forkhead Box Protein M1 | Colon cancer | Stem cells | Index Medicus | Abridged Index Medicus
Journal Article