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European Journal of Immunology, ISSN 0014-2980, 01/2016, Volume 46, Issue 1, pp. 70 - 80
The intestinal immune system is complex and displays unique anatomic and functional characteristics. Numerous immune cell subsets are located beneath the... 
Colitis | Homing receptor | T cell | Gut | Systemic IL‐12 | Systemic IL-12
Journal Article
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 09/2019, Volume 106, Issue 3, pp. 733 - 747
Host‐pathogen interactions in tuberculosis (TB) should be studied at the disease sites because Mycobacterium tuberculosis ( M.tb ) is predominantly contained... 
IL‐12 | M.tb | PD‐1 | T‐cell immune response | PD‐L1 | PD-L1 | IL-12 | PD-1 | T-cell immune response | Index Medicus
Journal Article
Viruses, 08/2019, Volume 11, Issue 9, p. 772
Members of the interleukin 12 (IL-12) family have been known to be inflammatory factors since their discovery. The IL-12 family consists of IL-12, IL-23,... 
interleukin (IL)-12 family | viral infection | immune systems
Journal Article
Dermatologic Therapy, ISSN 1396-0296, 05/2019, Volume 32, Issue 3, pp. e12843 - n/a
The molecular mechanism of ustekinumab action involves an interruption of signaling pathways activated by IL‐12/23. The aim of this paper was to evaluate the... 
IL 12 | IL 23 | ustekinumab | DERMATOLOGY | Psoriasis | Dermatology | Analysis | Formulae, receipts, prescriptions | Development and progression | Dermatologic agents | Drug therapy | Health aspects
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2010, Volume 5, Issue 2, pp. e9252 - e9252
In recent years it has become clear that the therapeutic properties of bone marrow-derived mesenchymal stromal cells (MSC) are related not only to their... 
IL-12 P40 HOMODIMER | INTERLEUKIN (IL)-12 | STEM-CELLS | INTERFERON-GAMMA | DENDRITIC CELLS | TRYPANOSOMA-CRUZI | IFN-GAMMA | MULTIDISCIPLINARY SCIENCES | APOPTOTIC CELLS | T-CELLS | ALTERNATIVE ACTIVATION | Tumor Necrosis Factor-alpha - metabolism | Coculture Techniques | Macrophages, Peritoneal - cytology | Mesenchymal Stromal Cells - cytology | Flow Cytometry | Inflammation Mediators - metabolism | Interleukin-10 - metabolism | Female | Cell Differentiation | Host-Parasite Interactions | Thymus Gland - metabolism | Cytokines - metabolism | Bone Marrow Cells - cytology | Mice, Inbred C57BL | Stromal Cells - metabolism | Cells, Cultured | Thymus Gland - cytology | Mesenchymal Stromal Cells - metabolism | Mice, Transgenic | Macrophages, Peritoneal - parasitology | Trypanosoma cruzi - physiology | Animals | Thioglycolates - pharmacology | Lipopolysaccharides - pharmacology | Mice | Macrophage Activation - drug effects | Macrophages, Peritoneal - metabolism | Bone Marrow Cells - metabolism | Phagocytosis | Stromal Cells - cytology | Apoptosis | Aspirin | Tumor necrosis factor | Stem cells | Hostages | Disease susceptibility | Interferon | Inflammation | Macrophages | Health aspects | Immunity | CD86 antigen | Mesenchyme | Prostaglandin E2 | Cytotoxicity | Infections | Acetylsalicylic acid | Kinases | Lipopolysaccharides | Recruitment | Interleukin 6 | Lymphocytes | Rodents | Bone marrow | Physiology | Growth factors | Cylinders | Immune response | Cytokines | Neutrophils | Implantation | Interleukin 12 | Tumor necrosis factor-α | Gene expression | CD4 antigen | Immune systems | Studies | Major histocompatibility complex | Thymocytes | Stromal cells | Interleukin 10 | Sepsis | Bone | Laboratory animals | Peritoneum | Index Medicus
Journal Article
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 11/2010, Volume 402, Issue 4, pp. 663 - 669
Dendritic cells (DCs) play an essential role in the induction and maintenance of an effective immune response and express multiple siglecs In the present study... 
Dendritic cell | Immunomodulation | PROGNOSIS | Siglec 9 | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLYCOPROTEINS | ANTIGEN PRESENTATION | MONOCLONAL-ANTIBODY | MATURATION | CANCER | Milan | BIOPHYSICS | IL 12 | INFECTION | SURGICAL RESECTION | INHIBITORS | EXPRESSION
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 12/2006, Volume 80, Issue 6, pp. 1298 - 1307
We generated three populations of macrophages (Mφ) in vitro and characterized each. Classically activated Mφ (Ca‐Mφ) were primed with IFN‐γ and stimulated with... 
IL‐12 | IL‐10 | sphingosine kinase | LIGHT | IL-10.IL-12 | Sphingosine kinase | TNF FAMILY MEMBER | IL-10-IL-12 | FC-GAMMA-RECEPTORS | IMMUNOLOGY | CELL BIOLOGY | IN-VITRO | REACTIVE OXYGEN | COSTIMULATORY SIGNALS | IMMUNE-RESPONSES | NITRIC-OXIDE | TUMOR-ASSOCIATED MACROPHAGES | HEMATOLOGY | T-CELLS | MONONUCLEAR PHAGOCYTES | Nerve Growth Factor - biosynthesis | Phosphotransferases (Alcohol Group Acceptor) - immunology | Coculture Techniques | Arginase - biosynthesis | Th2 Cells - immunology | Th1 Cells - immunology | Arginase - immunology | Nerve Growth Factor - immunology | B7-2 Antigen - immunology | Macrophages - immunology | Cytokines - immunology | Nitric Oxide - biosynthesis | Nitric Oxide - immunology | Macrophages - classification | Tumor Necrosis Factor Ligand Superfamily Member 14 - immunology | Macrophage Activation - immunology | Intercellular Signaling Peptides and Proteins | Tumor Necrosis Factor Ligand Superfamily Member 14 - biosynthesis | Cells, Cultured | Proteins - immunology | Macrophages - enzymology | Animals | Lipopolysaccharides - pharmacology | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Macrophage Activation - drug effects | Cytokines - biosynthesis | Cytokines - pharmacology | Phosphotransferases (Alcohol Group Acceptor) - biosynthesis | Index Medicus | IL-12 | IL-10
Journal Article
Immunology Letters, ISSN 0165-2478, 06/2019, Volume 210, pp. 20 - 28
We previously showed that recombinant eukaryotic initiation factor (LieIF) was able to induce the secretion of cytokines IL-12, IL-10 and TNF-α by human... 
Cellular vaccination | Dendritic cells | Maturation | Cytokine production | Leishmania eukaryotic initiation factor (LeIF) | INTRACELLULAR PATHOGEN | INTERLEUKIN (IL)-12 | PROTEIN | FACTOR-ALPHA PRODUCTION | IMMUNOLOGY | IL-12 | PROTECTIVE IMMUNITY | MAJOR INFECTION | TOLL-LIKE RECEPTORS | VISCERAL LEISHMANIASIS | ANTIGEN
Journal Article
Journal Article
European Journal of Immunology, ISSN 0014-2980, 06/2016, Volume 46, Issue 6, pp. 1343 - 1350
Interleukin‐12 family cytokines have emerged as critical regulators of immunity with some members (IL‐12, IL‐23) associated with disease pathogenesis while... 
Autoimmunity ⋅ IL‐12 ⋅ IL‐23p19 ⋅ IL‐27/IL‐35Ebi3 ⋅ IL‐39 ⋅ Inflammation ⋅ Systemic lupus erythematosus | Autoimmunity ⋅ IL-12 ⋅ IL-23p19 ⋅ IL-27/IL-35Ebi3 ⋅ IL-39 ⋅ Inflammation ⋅ Systemic lupus erythematosus | Autoimmunity | AUTOIMMUNE INFLAMMATION | REGULATORY B-CELLS | CD4(+) T-CELLS | INTERLEUKIN-23 | Inflammation | IMMUNOLOGY | IL-12 | IL-23 | ERYTHEMATOSUS | DISEASE-ACTIVITY | Systemic lupus erythematosus | IL-39 | SLE PATHOGENESIS | IL-27/IL-35Ebi3 | IL-12 FAMILY CYTOKINES | EXPRESSION | IL-23p19 | Inflammation - pathology | Protein Multimerization | Lupus Erythematosus, Systemic - metabolism | Receptors, Interleukin - metabolism | Interleukin-23 Subunit p19 - metabolism | Inflammation - metabolism | Lymphocyte Activation - immunology | Mice, Inbred MRL lpr | STAT1 Transcription Factor - metabolism | Interleukin-23 Subunit p19 - genetics | Minor Histocompatibility Antigens - genetics | Female | Receptors, Cytokine - metabolism | Receptors, Cytokine - genetics | B-Lymphocytes - metabolism | STAT3 Transcription Factor - metabolism | Disease Models, Animal | Gene Expression | Signal Transduction | Immunophenotyping | Lupus Erythematosus, Systemic - etiology | Interleukin-23 Subunit p19 - chemistry | Inflammation - etiology | Minor Histocompatibility Antigens - metabolism | Animals | B-Lymphocytes - immunology | Receptors, Cytokine - chemistry | Mice | Lupus Erythematosus, Systemic - pathology | Minor Histocompatibility Antigens - chemistry | Lupus | B cells | Cytokines | Index Medicus
Journal Article
Journal Article