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by Wang, XY and Yang, X and Wen, C and Gao, YJ and Qin, L and Zhang, SN and Zhang, AY and Yang, K and Zhou, H
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, ISSN 0145-305X, 06/2016, Volume 59, pp. 121 - 127
In the present study, effects of TGF-beta 1 on IL-1 beta signaling during inflammatory response were examined in grass carp. In grass carp head kidney... 
Grass carp | EXPRESSION ANALYSIS | TGF-beta 1 | IL-1 | INTERLEUKIN-1-BETA | Inflammatory response | IL-1 beta | FUNCTIONAL-CHARACTERIZATION | IMMUNOLOGY | RECEPTOR ANTAGONIST | CTENOPHARYNGODON-IDELLA | GROWTH-FACTOR-BETA | INHIBITION | ZOOLOGY | Antagonistic effect | MOLECULAR-CLONING | HEAD KIDNEY LEUKOCYTES
Journal Article
Journal of Neuroinflammation, ISSN 1742-2094, 10/2017, Volume 14, Issue 1, pp. 199 - 199
Background: Neuroinflammation in the brain consequent to activation of microglia is viewed as an important component of Alzheimer's disease (AD) pathology.... 
AC253 peptide | Cytokines | Amylin receptor | NLRP3 | Inflammasome | Alzheimer's disease | Caspase-1 | Microglia | β-amyloid | SIGNALING PATHWAYS | PROTEIN | ALZHEIMERS-DISEASE | CYTOKINE | IMMUNOLOGY | COGNITION | NEUROSCIENCES | beta-amyloid | PATHOGENESIS | PEPTIDES | NEUROINFLAMMATION | A-BETA | NEURONS | Inflammation - chemically induced | Microglia - metabolism | Peptide Fragments - toxicity | Humans | Caspase 1 - metabolism | Male | Peptides, Cyclic - pharmacology | Alzheimer Disease - pathology | Female | Receptors, Islet Amyloid Polypeptide - metabolism | Cyclic AMP - metabolism | Cytokines - genetics | Lipopolysaccharides - toxicity | Cytokines - metabolism | Microglia - drug effects | Amyloid beta-Peptides - toxicity | Gene Expression Regulation - genetics | NLR Family, Pyrin Domain-Containing 3 Protein - metabolism | Alzheimer Disease - therapy | Cells, Cultured | Mice, Transgenic | Fetus - cytology | Gene Expression Regulation - drug effects | Animals | Peptides, Cyclic - therapeutic use | Mice | Alzheimer Disease - genetics | Cell Line, Transformed | Physiological aspects | Development and progression | Genetic aspects | Research | Amyloid beta-protein | Brain | Cell culture | Calcium (intracellular) | Neurons | Therapeutic applications | Fetuses | Amylin | Transgenic mice | Inflammation | Fluorescent indicators | Tumor necrosis factor-α | Gene expression | IL-1β | Experiments | Lipopolysaccharides | Proteins | Polymerase chain reaction | Aging | β-Amyloid | Alzheimers disease | Index Medicus
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 08/2007, Volume 151, Issue 8, pp. 1272 - 1279
Background and purpose: Pharmacological inhibition of beta-amyloid (A beta) induced reactive gliosis may represent a novel rationale to develop drugs able to... 
cannabidiol | iNOS | IL‐1 | reactive gliosis | mice | GFAP | | Reactive gliosis | Cannabidiol | Mice | IL-1β | INTERLEUKIN-1 | NITRIC-OXIDE SYNTHASE | ALZHEIMERS-DISEASE | INVOLVEMENT | NEURODEGENERATION | TAU | IL-1 beta | A beta | HYPERPHOSPHORYLATION | PHARMACOLOGY & PHARMACY | PC12 CELLS | NF-KAPPA-B | CANNABINOIDS | Research Papers
Journal Article
by Yang, X and Wei, H and Qin, L and Zhang, SN and Wang, XY and Zhang, AY and Du, LY and Zhou, H
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, ISSN 0145-305X, 12/2014, Volume 47, Issue 2, pp. 197 - 204
In the present study, we found that recombinant grass carp IL-1 beta (rgcIL-1 beta) simultaneously upregulated grass carp IL-1 beta (gcIL-1 beta) and TOF-1... 
MOLECULAR CHARACTERIZATION | Grass carp | TGF-beta 1 | SEA BREAM | IL-1 beta | FUNCTIONAL-CHARACTERIZATION | Reciprocal interaction | IMMUNOLOGY | Head kidney leukocytes | POTENT INHIBITOR | GROWTH-FACTOR-BETA | ZOOLOGY | Signaling pathway | ORANGE-SPOTTED GROUPER | GROUPER EPINEPHELUS-COIOIDES | INFLAMMATORY RESPONSE | NF-KAPPA-B | INNATE IMMUNITY
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 02/2019, Volume 1865, Issue 2, pp. 275 - 284
Acute hyperglycemia is regarded as a risk factor for critically ill patients; however, insufficient understanding of its nature and underlying mechanisms... 
Glycemic control | Acute hyperglycemia | IL-1β | Pancreatic beta cell | Insulin secretion | MORTALITY | MANAGEMENT | GLUCOSE CONTROL | INTERLEUKIN-1-BETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | IL-1 beta | BURN | PROFILE | BIOPHYSICS | STRESS | INTENSIVE INSULIN THERAPY | CRITICALLY-ILL PATIENTS | EXPRESSION
Journal Article
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, ISSN 0145-305X, 11/2012, Volume 38, Issue 3, pp. 431 - 446
To date two closely related interleukin-1 beta genes (IL-1 beta 1 and IL-beta 2) have been found in salmonids. The cloning of trout and salmon IL-1 beta 3, and... 
PRO-INFLAMMATORY CYTOKINES | RAINBOW-TROUT | EXPRESSION ANALYSIS | IMMUNE CELLS | Type I IL-1 beta | Atlantic salmon | FUNCTIONAL-CHARACTERIZATION | IMMUNOLOGY | RECEPTOR ANTAGONIST | Type II IL-1 beta | GENOME DUPLICATION | FISHERIES | ZOOLOGY | Expression | GILTHEAD SEABREAM | Rainbow trout | Gene cloning | MOLECULAR-CLONING | TROUT ONCORHYNCHUS-MYKISS
Journal Article
Brain, Behavior, and Immunity, ISSN 0889-1591, 2014, Volume 41, Issue 1, pp. 90 - 100
Abstract Depression is an inflammatory disorder. Pro-inflammatory cytokine interleukin-1 beta (IL-1β) may play a pivotal role in the central nervous system... 
Psychiatry | Allergy and Immunology | Depression | IL-1β-related CNS inflammation | Chronic unpredictable mild stress | Prefrontal cortex | NLRP3 inflammasome | ANTIDEPRESSANT | CHRONIC MILD STRESS | CYTOKINE LEVELS | MAJOR DEPRESSION | IMMUNOLOGY | IL-1 beta-related CNS inflammation | FLUOXETINE | NEUROSCIENCES | TOLL-LIKE | DISORDER | ALTERED EXPRESSION | PITUITARY-ADRENAL AXIS | BRAIN | Microglia - metabolism | Rats, Wistar | Sucrose | Depressive Disorder - pathology | NLR Family, Pyrin Domain-Containing 3 Protein | Nerve Tissue Proteins - analysis | Stress, Physiological | Depressive Disorder - drug therapy | Male | NF-kappa B - metabolism | Receptors, Cytoplasmic and Nuclear - biosynthesis | Interleukin-1beta - blood | Prefrontal Cortex - pathology | Nerve Tissue Proteins - biosynthesis | Microglia - pathology | Interleukin-1beta - biosynthesis | Fluoxetine - therapeutic use | Carrier Proteins | Interleukin-1beta - physiology | Nerve Tissue Proteins - physiology | Calcium-Binding Proteins - analysis | Gene Expression Regulation | Interleukin-1beta - cerebrospinal fluid | Microfilament Proteins - analysis | Rats | Anhedonia | Receptors, Cytoplasmic and Nuclear - physiology | Inflammation | Random Allocation | Depressive Disorder - metabolism | Drinking Behavior | Antidepressive Agents - therapeutic use | Inflammasomes - physiology | Animals | Receptors, Cytoplasmic and Nuclear - analysis | Prefrontal Cortex - metabolism | Enzyme Activation | Chronic Disease | Index Medicus
Journal Article
FEBS Letters, ISSN 0014-5793, 04/2012, Volume 586, Issue 7, pp. 984 - 989
► Differential usage of IKK complex components by IL-1β and TNF-α in beta cells. ► The IKK complex induced by IL-1β in beta cells lacks the IKKβ subunit. ►... 
NF-κB | Pancreatic β-cell | IKK complex | Interleukin-1β | Cytokine | knock down | jun N-terminal kinase | JNK | IKK | IL-1β | IκB kinase | interleukin-1β | TNF-α | tumor necrosis factor-α | KINASE-ALPHA | INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | IKK-BETA | Interleukin-1 beta | CELL BIOLOGY | Pancreatic beta-cell | NF-kappa B | BIOPHYSICS | INFLAMMATION | GENE-EXPRESSION | DEREPRESSION | INS-1 CELLS | TYPE-1 | MODULATION | Tumor Necrosis Factor-alpha - metabolism | Rats, Wistar | Humans | Tumor Necrosis Factor-alpha - genetics | NF-kappa B - metabolism | Molecular Targeted Therapy | Protein Subunits - metabolism | Protease Inhibitors - pharmacology | Proteolysis - drug effects | Insulin-Secreting Cells - metabolism | I-kappa B Kinase - metabolism | I-kappa B Kinase - antagonists & inhibitors | Interleukin-1beta - metabolism | Insulin-Secreting Cells - cytology | Protein Subunits - genetics | Recombinant Proteins - metabolism | Cell Line | Cells, Cultured | Gene Silencing | Rats | I-kappa B Kinase - genetics | Diabetes Mellitus, Type 1 - drug therapy | Animals | Insulin-Secreting Cells - drug effects | Signal Transduction - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Protein Subunits - antagonists & inhibitors | Proteasome Endopeptidase Complex - metabolism | Proteasome Inhibitors | Index Medicus
Journal Article