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Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2017, Volume 76, Issue Suppl 2, p. 281
BackgroundJAK1, 2, 3 and TYK2 are cytoplasmic tyrosine kinases that mediate intracellular signaling of many cytokines and growth factors. Filgotinib (GLPG0634,... 
Biomarkers | IL-1β
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2017, Volume 76, Issue Suppl 2, p. 648
BackgroundAnkylosing spondylitis (AS) is a chronic inflammatory disease, of unknown aetiology, associated to the development of several comorbidities such as... 
Biomarkers | IL-1β
Journal Article
Redox biology, ISSN 2213-2317, 2015, Volume 4, Issue C, pp. 296 - 307
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2017, Volume 76, Issue Suppl 2, p. 721
BackgroundDuring macrophage activation syndrome (MAS), an inflammatory life-threatening syndrome, extremely high levels of serum ferritin may be observed [1].... 
Macrophages | IL-1β | Rheumatic diseases
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 10/2017, Volume 70, Issue 16, pp. C43 - C43
The expressions of leptin receptor (LepRb) mRNA, phosphorylated signal transducer and activator of transcription-3(p-STAT3), phosphorylated... 
Hypertension | Obesity | Hypotheses | Cytokines | IL-1β | Rodents
Journal Article
Journal Article
Journal Article
Annual review of immunology, ISSN 1545-3278, 2009, Volume 27, Issue 1, pp. 621 - 668
The autoinflammatory diseases are characterized by seemingly unprovoked episodes of inflammation, without high-titer autoantibodies or antigen-specific T... 
Pulmonary fibrosis | Atherosclerosis | Innate immunity | Crohn's disease | Inflammasome | Type 2 diabetes mellitus | IL-1β | Ankylosing spondylitis | atherosclerosis | HEMOLYTIC-UREMIC SYNDROME | INTERLEUKIN-1 RECEPTOR ANTAGONIST | ankylosing spondylitis | JUVENILE IDIOPATHIC ARTHRITIS | IL-1 beta | INNATE IMMUNE-SYSTEM | ENDOPLASMIC-RETICULUM STRESS | IMMUNOLOGY | ENCODING MEVALONATE KINASE | UNFOLDED PROTEIN RESPONSE | innate immunity | FAMILIAL MEDITERRANEAN FEVER | inflammasome | MACROPHAGE ACTIVATION SYNDROME | pulmonary fibrosis | type 2 diabetes mellitus | NF-KAPPA-B | Tumor Necrosis Factor-alpha - metabolism | Phosphotransferases (Alcohol Group Acceptor) - immunology | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Tumor Necrosis Factor-alpha - genetics | NF-kappa B - immunology | NF-kappa B - metabolism | Interleukin-1beta - genetics | Autoimmune Diseases - genetics | Interleukin-1beta - metabolism | Tumor Necrosis Factor-alpha - immunology | Cytokines - genetics | Carrier Proteins - immunology | Cytokines - immunology | Autoimmune Diseases - classification | Cytokines - metabolism | Autoimmune Diseases - immunology | Interleukin-1beta - immunology | Phosphotransferases (Alcohol Group Acceptor) - genetics | Inflammation - immunology | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | NF-kappa B - genetics | Inflammation - classification | Inflammation - genetics | Crohn’s disease
Journal Article