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Immunity, ISSN 1074-7613, 2010, Volume 32, Issue 1, pp. 91 - 103
CD25, the high-affinity interleukin-2 (IL-2) receptor α chain, is rapidly upregulated by antigen-specific CD8 T cells after T cell receptor stimulation. Here,... 
IMMUNITY | ACTIVATION | BLIMP-1 | MEMORY | CLONAL EXPANSION | GENE-EXPRESSION | PERFORIN | PROLIFERATION | IMMUNOLOGY | IL-2 RECEPTOR | LYMPHOCYTES
Journal Article
Journal of Immunology, ISSN 0022-1767, 02/2012, Volume 188, Issue 3, pp. 976 - 980
The transcription factor Helios has been reported to be a marker of regulatory T cells (Treg) of thymic origin, distinguishing them from Treg induced in the... 
FAMILY-MEMBER | TGF-BETA | RECOGNITION | IKAROS | IL-2 | DIFFERENTIATION | INDUCTION | IMMUNOLOGY | RECEPTORS | LINEAGE | CUTTING EDGE | Tissue Distribution | T-Lymphocytes, Regulatory - metabolism | Animals | Antigen-Presenting Cells | Ikaros Transcription Factor - biosynthesis | Mice, Transgenic | Mice | Forkhead Transcription Factors | Peptides - administration & dosage
Journal Article
Immunological Reviews, ISSN 0105-2896, 05/2009, Volume 229, Issue 1, pp. 12 - 26
T‐cell activation is mediated by antigen‐specific signals from the TCRζ/CD3 and CD4–CD8–p56lck complexes in combination with additional co‐signals provided by... 
CD28 | CTLA‐4 | apoptosis | PKB/AKT | TRIM | CTLA-4 | Apoptosis | LYMPHOCYTE-ASSOCIATED ANTIGEN-4 | FUNCTION IN-VIVO | PKB | KINASE-C-THETA | IL-2 PROMOTER ACTIVATION | PHOSPHATIDYLINOSITOL 3-KINASE | AKT | IMMUNOLOGY | ALDRICH-SYNDROME PROTEIN | T-CELL-RECEPTOR | CLATHRIN-ASSOCIATED PROTEIN | IMMUNOLOGICAL SYNAPSE | NF-KAPPA-B | Inducible T-Cell Co-Stimulator Protein | Antigens, CD - immunology | Humans | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - immunology | Antigens, CD - metabolism | CD28 Antigens - metabolism | Signal Transduction - immunology | Lymphocyte Activation - immunology | T-Lymphocytes - metabolism | Adaptor Proteins, Signal Transducing - immunology | Microfilament Proteins - metabolism | Contractile Proteins - metabolism | 3-Phosphoinositide-Dependent Protein Kinases | Protein-Serine-Threonine Kinases - metabolism | Antigens, Differentiation, T-Lymphocyte - immunology | Antigens, Differentiation, T-Lymphocyte - metabolism | CD28 Antigens - immunology | Filamins | CTLA-4 Antigen | Animals | Microfilament Proteins - immunology | Contractile Proteins - immunology | Protein-Serine-Threonine Kinases - immunology | T-Lymphocytes - immunology | Adaptor Proteins, Signal Transducing - metabolism | Autoimmunity | Phosphatidylinositol | Phosphatases | T cells | Protein kinases
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2010, Volume 185, Issue 1, pp. 174 - 182
Journal Article
Journal of Immunology, ISSN 0022-1767, 2008, Volume 180, Issue 11, pp. 7221 - 7229
Granulysin is a cytolytic effector molecule used by lymphocytes to kill tumor and microbial cells. Regulation of granulysin production is complex. A... 
BETA-CHAIN | TRANSCRIPTION FACTORS | RECEPTOR-GAMMA CHAIN | HUMAN-LYMPHOCYTES | SIGNALING PATHWAYS | PHOSPHATIDYLINOSITOL 3-KINASE | CRYPTOCOCCUS-NEOFORMANS | INTERLEUKIN-2 RECEPTOR | IMMUNOLOGY | IL-2 RECEPTOR | BLOOD MONONUCLEAR-CELLS
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 08/2012, Volume 13, Issue 8, pp. 770 - 770
CD4(+) interleukin 17 (IL-17)-producing helper T cells (T(H)17 cells) are instrumental in the immune response to pathogens. However, an overactive T(H)17... 
INTERLEUKIN-2 | GENE | ARYL-HYDROCARBON RECEPTOR | HELPER-CELLS | ROR-GAMMA | IN-VIVO | TRANSCRIPTION | REGULATORY T-CELLS | IL-2 | IMMUNOLOGY | TH17 CELLS
Journal Article