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The FEBS Journal, ISSN 1742-464X, 06/2017, Volume 284, Issue 11, pp. 1712 - 1725
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 03/2017, Volume 114, Issue 13, pp. E2748 - E2757
The proinflammatory cytokine IL-36. is highly expressed in epithelial cells and is a pivotal mediator of epithelial inflammation. In particular, IL-36. is... 
cytokine | GENERALIZED PUSTULAR PSORIASIS | RHEUMATOID-ARTHRITIS | ANTAGONIST IL-36RA | INTERLEUKIN-1 FAMILY | IL-1 | MULTIDISCIPLINARY SCIENCES | MONOCYTES | IL-36 | PROTEOLYSIS | inflammation | psoriasis | IL-1-BETA | SECRETION | EXPRESSION | SKIN INFLAMMATION | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
Kidney International, ISSN 0085-2538, 03/2018, Volume 93, Issue 3, pp. 599 - 614
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2017, Volume 114, Issue 13, pp. E2748 - E2757
Journal Article
Infection and immunity, ISSN 0019-9567, 01/2019, Volume 87, Issue 1
Legionella pneumophila causes life-threatening pneumonia culminating in acute lung injury. Innate and adaptive cytokines play an important role in host defense... 
Legionella pneumophila | macrophages | IL-36 | pneumonia | INFECTIOUS DISEASES | ACTIVATION | AERUGINOSA | LEGIONNAIRES-DISEASE | IMMUNOLOGY | MATURATION | RECIPIENTS | CELL-DEATH | INFECTION | MEDIATORS | MACROPHAGE POLARIZATION | EXPRESSION | Index Medicus
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 03/2017, Volume 137, Issue 3, pp. 696 - 705
IL-6 inhibition has been unsuccessful in treating psoriasis, despite high levels of tissue and serum IL-6 in patients. In addition, de novo psoriasis onset has... 
Cytokines - metabolism | Interleukin-6 - genetics | Skin - metabolism | Humans | Mice, Inbred C57BL | Interleukin-17 - genetics | Male | Inflammation | Mice, Knockout | Phenotype | Psoriasis - genetics | Animals | Keratinocytes - metabolism | Psoriasis - metabolism | Female | Mice | Skin - pathology | Index Medicus | IL-36 | mouse model | psoriasis | IL-6 | IL-17
Journal Article
Journal Article
International Immunopharmacology, ISSN 1567-5769, 06/2019, Volume 71, pp. 164 - 168
Glaucoma eventually leads to optic nerve damage and vision loss without medical intervention. More than 50% of glaucoma caused blindness are attributed to... 
IL-38 | IL-37 | IL-36 | Chronic primary angle closure glaucoma | Aqueous humor | Glaucoma | Inflammatory bowel diseases | Optic nerve | Cytokines | Pathogenesis | Visual field | Inflammatory diseases | Immunology | Intestine | Blindness | Uveitis | Immune privilege | Visual fields | Age
Journal Article
Journal Article
Cell Reports, ISSN 2211-1247, 03/2018, Volume 22, Issue 11, pp. 2937 - 2950
Neutrophil granule proteases are thought to function as anti-microbial effectors, cooperatively hydrolyzing microorganisms within phagosomes, or upon... 
elastase | microbial killing | cell death | inflammation | necrosis | IL-1 family | cathepsin G | IL-36 | IL-33 | neutrophil | ACTIVATION | SERINE PROTEASES | FAMILY CYTOKINES | INTERLEUKIN-1-BETA | ELASTASE | PAPILLON-LEFEVRE-SYNDROME | PROTEOLYSIS | INFLAMMATORY RESPONSE | CLEAVAGE | CELL-DEATH | CELL BIOLOGY | Index Medicus
Journal Article
FEBS Open Bio, ISSN 2211-5463, 05/2018, Volume 8, Issue 5, pp. 751 - 763
IL‐1 family cytokines act as apical initiators of inflammation in many settings and can promote the production of a battery of inflammatory cytokines,... 
elastase | protease | 1 family | 36 | inflammation | psoriasis | IL-1 family | IL-36 | MEMBERS | DERMATITIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | IL-36-GAMMA | LIGANDS | FAMILY CYTOKINES | REGULATORS | ALPHA-1-ANTITRYPSIN DEFICIENCY | NF-KAPPA-B | AGONIST
Journal Article