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Experimental Neurology, ISSN 0014-4886, 01/2020, Volume 323, p. 113082
Chitinase 3-like 1 (Chi3L1) plays a major role in the pathogenesis of inflammatory diseases. We investigated the effect of Chi3L1 knockout on stroke... 
Ischemia/reperfusion injury | Chitinase 3-like 1 | Inflammation | STAT6 | M2 polarization | Macrophage | IL-4Rα
Journal Article
Cell, ISSN 0092-8674, 09/2017, Volume 171, Issue 1, pp. 217 - 228.e13
Journal Article
Cancer Epidemiology Biomarkers & Prevention, ISSN 1055-9965, 11/2007, Volume 16, Issue 11, pp. 2448 - 2454
Previous studies found that allergies are inversely related to risk of glioma. In an earlier publication, using data from a Swedish case-control study,... 
allergies | glioblastoma | COX-2 | asthma | IL-13 | polymorphisms | IL-4Rα
Journal Article
mAbs, ISSN 1942-0862, 07/2019, Volume 11, Issue 5, pp. 837 - 847
Asthma is characterized by airway hyperresponsiveness and inflammation, as well as underlying structural changes to the airways. Interleukin-4 (IL-4) is a key... 
Th2 cytokines | Monocytes | IgE | IL-4 | Antibody therapy | CD23 | IL-4Rα | Asthma | FcαR | CD32
Journal Article
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 8/2009, Volume 183, Issue 3, pp. 1607 - 1616
Several commonly occurring polymorphisms in the IL-4Rα have been associated with atopy in humans; the Q576R and the S503P polymorphisms reside in the... 
IL-4 | STAT6 | polymorphisms | IL-4Rα
Journal Article
Cell Reports, ISSN 2211-1247, 05/2019, Volume 27, Issue 8, pp. 2442 - 2458.e5
Adaptive type 2 immune responses against the intestinal helminth require the interaction of follicle-associated CXCR5 dendritic cells with naive T cells in the... 
MAdCAM-1 | interfollicular region | fibroblastic reticular cells | helminth infection | mesenteric lymph node | marginal reticular cells | Heligmosomoides polygyrus | CXCL13 | intestinal infection | IL-4Rα | DETERMINES | HOMEOSTASIS | DENDRITIC CELLS | ANTIBODY-PRODUCTION | LYMPH-NODES | REGULATORY T-CELLS | TRAFFICKING | CHEMOKINE | CCR7 | LYMPHOTOXIN | CELL BIOLOGY
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 02/2019, Volume 105, Issue 2, pp. 307 - 316
Development of IL‐4 receptor alpha (IL‐4Rα)‐dependent cellular immunity regulates host protection against acute schistosomiasis. In this study, we investigated... 
acute | CD11c+ cells | IL‐4Rα | immunity | schistosomiasis | mice | cells | CD11c | IL-4Rα | DENDRITIC CELLS | INTERLEUKIN (IL)-4 | IMMUNOBIOLOGY | IL-4 RECEPTOR | IL-4R alpha | IMMUNOLOGY | MACROPHAGE ACTIVATION | HEPATIC-FIBROSIS | CELL BIOLOGY | GRANULOMATOUS PATHOLOGY | RESISTANCE | HEMATOLOGY | CD11c(+) cells | POLARIZATION | T-CELLS | 10th FAIS‐African Immunology Congress (FAIS), December 3–7, 2017, Hammamet, Tunisia
Journal Article
Experimental Cell Research, ISSN 0014-4827, 2009, Volume 315, Issue 20, pp. 3486 - 3499
Oncostatin M (OSM), a pleiotropic cytokine and a member of the gp130/IL-6 cytokine family, has been implicated in regulation of various chronic inflammatory... 
Fibroblasts | IL-13Rα1 | Eotaxin-1 | Oncostatin M | IL-4Rα
Journal Article
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 08/2019, Volume 10, p. 1957
Previous studies infecting global IL-4R alpha(-/-), IL-4(-/-), and IL-13(-/-) mice on a BALB/c background with the visceralizing parasite Leishmania donovani... 
ALTERNATIVE MACROPHAGE ACTIVATION | Leishmania donovani | T cell | SUSCEPTIBILITY | IL-4 | ACQUIRED-RESISTANCE | IL-4R alpha | DEFICIENT MICE | INTERLEUKIN-10 | IMMUNOLOGY | mice | DONOVANI INFECTION | CHEMOTHERAPY | T-HELPER-1 RESPONSES | DISRUPTION | IN-VIVO | IL-4Rα
Journal Article