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British Journal of Clinical Pharmacology, ISSN 0306-5251, 02/2019, Volume 85, Issue 2, pp. 304 - 315
Aim Interleukin (IL)‐7 signalling modulates T cell activity and is implicated in numerous autoimmune diseases. The present study investigated the safety,... 
pharmacokinetics | immunology | pharmacodynamics | drug safety | monoclonal antibodies | SURVIVAL | PRIMARY SJOGRENS-SYNDROME | TH17 CYTOKINE PRODUCTION | SALIVARY-GLANDS | CD8 T-CELLS | INTERLEUKIN-7 | IL-7 | CONCISE GUIDE | PHARMACOLOGY & PHARMACY | BLOCKADE | EXPRESSION | Original
Journal Article
Experimental Parasitology, ISSN 0014-4894, 11/2007, Volume 117, Issue 3, pp. 304 - 317
Schistosome parasites have co-evolved an intricate relationship with their human and snail hosts as well as a novel interplay between the adult male and female... 
e2IFα | GPI | extracellular signal-regulated kinase | histone acetyltransferase | latency associated protein | short interfering RNA | SmInACT | transforming growth factor β-induced gene-human clone 3 | anti-Mullerian hormone | RT-PCR | Common-Smads | cDNA | CREB binding protein | TβRII | AMH | TGF-b type I receptor | beta-ig-h3 | receptor kinase | Schistosoma mansoni | TβRI | GCN5 | RNAi | Schistactivin receptor-like kinasesosoma mansoni | GS region | Co-Smads | alternating glycine and serine residues | GDFs | FK506-binding protein | growth/differentiation factors | MAPK | N-terminal extracellular domain | IL-7 | BMPs | activin type Ib receptor | receptor-regulated Smads | Smad | SIP | ERK | RNA interference | Smad anchor for receptor activation | transforming growth factor beta | I-Smads | complementary deoxyribonucleic acid | Interleukin-7 | ActRIb | EGFR | Host–parasite interactions | CBP | mitogen-activated protein kinase | Mad homology region | reverse transcriptase polymerase chain reaction | TGF-β | general control nonderepressible-5 protein | SARA | SmRK1-interacting protein | human | bone morphogenetic proteins | SmInhibin/activin-like molecule | eukaryotic translation initiation factor 2α subunit | epidermal growth factor receptor | ECD | inhibitory Smads | siRNA | gynecophoral canal protein | ALKs | Male–female interactions | FKBP | GCP | LTBP | R-Smads | activin receptor-like kinases | TGF-b type II receptor | HAT | LAP | glycosylphosphatidylinositol | latent TGF-β binding protein | Male-female interactions | Host-parasite interactions | ECD, N-terminal extracellular domain | HAT, historic acetyltransferase | CELL-MEMBRANE | RNAi, RNA interference | ALKs, activin receptor-like kinases | e2IF alpha, eukaryotic translation initiation factor 2 alpha subunit | RECEPTOR SERINE/THREONINE KINASE | TGF-beta | MAD-RELATED PROTEIN | SIP, SmRK1-interacting protein | TGF-beta, transforming growth factor beta | PARASITOLOGY | male-female interactions | IL-7, Interleukin-7 | SARA, Smad anchor for receptor activation | SMAD PROTEINS | CRYSTAL-STRUCTURE | AMH, anti-Mullerian hormone | CBP, CREB binding protein | FKBP, FK506-binding protein | RK, receptor kinase | EGFR, epidermal growth factor receptor | SmInACT, SmInhibin/activin-like molecule | cDNA, complementary deoxyribonucleic acid | MH, Mad homology region | GDFs, growth/differentiation factors | Sm, Schistosoma mansoni | GCP, gynecophoral canal protein | LTBP, latent TGF-beta binding protein | MAPK, mitogen-activated protein kinase | RT-PCR, reverse transcriptase polymerase chain reaction | h, human | beta-ig-h3, transforming growth factor beta-induced gene-human clone 3, Host-parasite interactions | siRNA, short interfering RNA | REPRODUCTIVE DEVELOPMENT | GS region, alternating glycine and serine residues | GCN5, general control nonderepressible-5 protein | DNA-BINDING | I-Smads, inhibitory Smads | ActRIb, activin type Ib receptor | BMPs, bone morphogenetic proteins | Co-Smads, Common-Smads | GPI, glycosylphosphatidylinositol | HISTONE ACETYLTRANSFERASE | T beta RII, TGF-b type II receptor | GROWTH-FACTOR-BETA | ERK, extracellular signal-regulated kinase | R-Smads, receptor-regulated Smads | HOST-PARASITE RELATIONSHIPS | LAP, latency associated protein | T beta RI, TGF-b type I receptor | Schistosoma mansoni - physiology | Protein-Serine-Threonine Kinases - physiology | Humans | Transforming Growth Factor beta - physiology | Reproduction - physiology | Skin - parasitology | Male | Smad Proteins - physiology | Animals | Schistosomiasis mansoni - parasitology | Snails - parasitology | Helminth Proteins - physiology | Sex Factors | Female | Ligands | Signal Transduction - physiology | Host-Parasite Interactions | Liver - parasitology | Schistosoma mansoni - growth & development | Life Cycle Stages - physiology
Journal Article
Journal Article
Nature Immunology, ISSN 1529-2908, 02/2009, Volume 10, Issue 2, pp. 176 - 184
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 10/2010, Volume 202, Issue 8, pp. 1254 - 1264
Journal Article
Frontiers in immunology, ISSN 1664-3224, 2019, Volume 10, p. 140
In lymphopenic mice, T cells become activated and undergo lymphopenia-induced proliferation (LIP). However, not all T cells are equally sensitive to... 
interferon-γ | dendritic cells | CD4+ T cells | lymphopenia-induced proliferation (LIP) | lymphopenia | SURVIVAL | COMMENSAL MICROFLORA | CD8(+) | INDUCTION | IMMUNOLOGY | NAIVE | HOMEOSTATIC PROLIFERATION | CUTTING EDGE | IL-7 | DIFFERENTIATION | CD4(+) T cells | interferon-gamma | EXPRESSION
Journal Article