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Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 03/2014, Volume 34, Issue 3, pp. 552 - 564
OBJECTIVE—Interleukin 1 Receptor 1 (IL1R1) and its ligand, IL1β, are upregulated in cardiovascular disease, obesity, and infection. Previously, we reported a... 
Infection | Diet, high-fat | Megakaryocytes | Blood platelets | IL1R1 protein, human | THROMBOPOIESIS | CELLS | blood platelets | infection | megakaryocytes | HIGH-FAT DIET | CANAKINUMAB | ATHEROSCLEROSIS | IL1R1 protein | ARTERIES | CYTOKINE PRODUCTION | INHIBITION | high-fat | PERIPHERAL VASCULAR DISEASE | IL-1-BETA | diet | HEMATOLOGY | human | EXPRESSION | Inflammation - pathology | Transcription, Genetic - drug effects | Interleukin-1beta - pharmacology | Receptors, Interleukin-1 Type I - physiology | Humans | Platelet Activation - physiology | Platelet Adhesiveness - physiology | NF-kappa B - metabolism | Gene Expression Profiling | Obesity - blood | Obesity - genetics | Atherosclerosis - etiology | Bacteroidaceae Infections - blood | Thrombin - pharmacology | Protein Processing, Post-Translational - drug effects | Collagen - pharmacology | p38 Mitogen-Activated Protein Kinases - metabolism | Phosphorylation - drug effects | Megakaryocytes - cytology | Proto-Oncogene Proteins c-akt - metabolism | Bacteroidaceae Infections - pathology | Disease Models, Animal | Receptors, Interleukin-1 Type I - deficiency | Porphyromonas gingivalis | Cell Line | Interleukin-1beta - physiology | Obesity - complications | Imidazoles - pharmacology | Inflammation - etiology | Mice, Knockout | Platelet Adhesiveness - drug effects | Transcription, Genetic - physiology | Animals | MAP Kinase Signaling System - drug effects | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Receptors, Interleukin-1 Type I - genetics | Inflammation - genetics | Mice | Platelet Activation - drug effects | Pyridines - pharmacology | Dietary Fats - toxicity | Index Medicus
Journal Article
Chinese Journal of Contemporary Pediatrics, ISSN 1008-8830, 03/2016, Volume 18, Issue 3, pp. 243 - 246
Journal Article
Cell Reports, ISSN 2211-1247, 05/2018, Volume 23, Issue 8, pp. 2318 - 2329
T helper 17 (Th17) cell development is programmed by the orphan nuclear receptor RORγt, but the underlying mechanism is not well understood. Nuclear... 
p300 | IL1R1 | steroid receptor coactivator-3 | EAE | pathogenic Th17 | RORγt | IL17A | Index Medicus
Journal Article
International Journal of Pharmacy and Pharmaceutical Sciences, 2016, Volume 8, Issue 5, pp. 109 - 112
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 512, Issue 1, pp. 69 - 73
Rheumatoid arthritis is a chronic autoinflammatory disease that affects 1-2% of the world's population and is characterized by widespread joint inflammation.... 
RHEUMATOID-ARTHRITIS | COLLAGEN-INDUCED ARTHRITIS | ACTIVATION | 6Q23 | CASPASE-1 | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | MICE | INHIBITOR | NF-KAPPA-B | ASSOCIATION | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Caspase 1 - metabolism | Male | Intracellular Signaling Peptides and Proteins - metabolism | Intracellular Signaling Peptides and Proteins - deficiency | Arthritis, Rheumatoid - metabolism | Arthritis, Rheumatoid - prevention & control | Cysteine Endopeptidases - metabolism | Receptors, Interleukin-1 - deficiency | Cysteine Endopeptidases - deficiency | Female | Tumor Necrosis Factor alpha-Induced Protein 3 | DNA-Binding Proteins | Disease Models, Animal | Calcium-Binding Proteins - metabolism | Interleukin-1 - metabolism | Signal Transduction | Nuclear Proteins - metabolism | Apoptosis Regulatory Proteins - metabolism | Arthritis, Rheumatoid - pathology | Mice, Knockout | Receptors, Interleukin-1 - metabolism | Macrophages - metabolism | Phenotype | Animals | Carrier Proteins - metabolism | Caspase 1 - deficiency | Mice | Arthritis, Rheumatoid - immunology | Prevention | Rheumatoid arthritis | Physiological aspects | NLRP3 | Properties | Macrophages | Risk factors | Proteins | Pathology | Dehydrogenases | Histopathology | Pathogenesis | Rodents | Protein expression | Index Medicus | Nlrp3 | IL1R1 | caspase-1 | inflammasome | A20
Journal Article
by Na, YY and Bai, R and Ren, YZ and Zhao, ZQ and Kong, LY and Li, RF and Han, CX and Jia, HS
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, ISSN 1936-2625, 2018, Volume 11, Issue 7, pp. 3759 - 3764
Several studies have demonstrated that polymorphisms within the IL-1 gene cluster are associated with the risk of ankylosing spondylitis (AS) in different... 
INTERLEUKIN-1 | GENE | ONCOLOGY | IL1R1 | case-control study | ERAP1 | SNPs | INDUCED ARTHRITIS | PATHOLOGY | genetic susceptibility
Journal Article
Oncotarget, ISSN 1949-2553, 02/2017, Volume 8, Issue 31, pp. 50673 - 50679
Aim: IgA nephropathy (IgAN) is the major cause of end-stage renal disease(ESRD) in Asia and its pathogenesis is influenced by both genetic and environmental... 
IL-1R2 | IgA nephropathy | IL-1R1 | Genetics polymorphism | Chinese Han population | INTERLEUKIN-1 | IL1R1 | SUSCEPTIBILITY LOCI | RECEPTOR | FAMILY | CELL BIOLOGY | genetics polymorphism | EXPRESSION | GENOME-WIDE ASSOCIATION
Journal Article
Oncotarget, ISSN 1949-2553, 10/2018, Volume 9, Issue 84, pp. 35480 - 35492
Recent molecular subgrouping of ependymomas (EPN) by DNA methylation profiling has identified ST-EPN- and PF-EPN-A subgroups to be associated with poor... 
IL1R1 | Co-expression study | PF-EPN-A molecular groups | ST-EPN-RELA | Slug | Snail | Ependymoma
Journal Article
Bioscience reports, ISSN 0144-8463, 12/2018, Volume 38, Issue 6, p. BSR20180598
Lower extremity deep vein thrombosis (LEDVT), a common peripheral vascular disease caused by a blood clot in a deep vein is usually accompanied by swelling of... 
TLR4 signaling pathway | MicroRNA-495 | IL1R1 | Femoral vein | Cell cycle | Lower extremity deep vein thrombosis | MIGRATION | ENDOTHELIAL PROGENITOR CELLS | APOPTOSIS | ACTIVATION | CANCER CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | RESISTANCE | PROLIFERATION | MODEL | PROMOTES | CELL BIOLOGY
Journal Article
Cell Reports, ISSN 2211-1247, 03/2017, Volume 18, Issue 13, pp. 3204 - 3218
Journal Article
The Journal of Gene Medicine, ISSN 1099-498X, 10/2018, Volume 20, Issue 10-11, pp. e3057 - n/a
Journal Article
Allergy, Asthma and Immunology Research, ISSN 2092-7355, 2016, Volume 8, Issue 5, pp. 466 - 470
Purpose: Interleukin-1 (IL-1) plays a key role in inflammation and immunity and its decoy receptor, IL-1R2, has been implicated in transcriptomic and genetic... 
Genetic | SNPxSNP | IL1R1 | IL1R2 | Asthma | Atopy | genetic | POLYMORPHISMS | ALLERGY | GENETICS | IL-1 | asthma | IMMUNOLOGY | SNP×SNP | Brief Communication
Journal Article
Journal Article