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OncoImmunology, ISSN 2162-4011, 06/2019, Volume 8, Issue 6, p. e1238538
The humanized immunocytokine, hu14.18-IL2 (ICp), leads to the immune cell-mediated destruction of GD2-expressing tumors in mouse models, resulting in potent... 
IL2 receptors | IL2 toxicity | immunocytokines | Immunotherapy | IL2 | NATURAL-KILLER-CELLS | SEVERE COMBINED IMMUNODEFICIENCY | RECOMBINANT HUMAN INTERLEUKIN-2 | INTERLEUKIN-2-RECEPTOR BETA-CHAIN | MONOCLONAL-ANTIBODY | IMMUNOLOGY | I CLINICAL-TRIAL | GAMMA-CHAIN | INTERMEDIATE-AFFINITY | ONCOLOGY | HUMAN NEUROBLASTOMA METASTASES | IL-2 RECEPTOR
Journal Article
Oncotarget, ISSN 1949-2553, 07/2018, Volume 9, Issue 54, pp. 30268 - 30278
Early in the course of immunotherapy there is frequently a transient enlargement of tumor masses (pseudo-progression) due to tumor infiltration by TILs.... 
Pembrolizumab | Check point inhibitors | Ipilimumab | Tc-IL2 | Melanoma
Journal Article
Cancer research, ISSN 0008-5472, 11/2017, Volume 77, Issue 21, pp. 5938 - 5951
Interleukin-2 (IL2) is an immunostimulatory cytokine for key immune cells including T cells and natural killer (NK) cells. Systemic IL2 supplementation could... 
Natural killer cells | NK cells expansion | Cancer immunotherapy | tumor | IL2 | IL2 receptor
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 5/2017, Volume 23, Issue 9, pp. 2159 - 2168
Journal Article
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 02/2017, Volume 18, Issue 2, pp. 577 - 582
Objective: In this study, expression of Interleukin-2, Interleukin-4, Interleukin-10 and transforming growth factor beta in diffuse and intestinal type gastric... 
Gastric adenocarcinoma- Cytokines- IL2- IL4- IL10- TGFβ | IL4 | IL10 | TGFβ | Gastric adenocarcinoma | Cytokines | IL2
Journal Article
Viruses, ISSN 1999-4915, 10/2019, Volume 11, Issue 10, p. 921
Sterile alpha motif and histidine/aspartic domain-containing protein 1 (SAMHD1) is a protein with anti-viral, anti-neoplastic, and anti-inflammatory... 
pSAMHD1 | restriction factor | triphosphohydrolase | interferon | interleukin | phosphorylation | IL2
Journal Article
Transfusion and Apheresis Science, ISSN 1473-0502, 12/2018, Volume 57, Issue 6, pp. 779 - 784
Hemophagocytic lymphohistiocytosis (HLH) in adults is rare but frequently fatal. Diagnosis is often delayed and treatment approaches vary significantly in... 
Hemophagocytic lymphohistiocytosis | Epstein-Barr virus | Soluble IL2 receptor | Lymphoma
Journal Article
Fish and Shellfish Immunology, ISSN 1050-4648, 10/2019, Volume 93, pp. 1018 - 1027
In our previous study, a DNA plasmid encoding the VAA gene of was constructed and demonstrated to confer moderated protection against challenge. Here, a... 
Vibrio anguillarum | Immune response | Bicistronic DNA vaccine | Paralichthys olivaceus | IL2
Journal Article
Journal Article
Gene Therapy and Molecular Biology, ISSN 1529-9120, 2014, Volume 16, Issue 1, pp. 1 - 9
CLL | MLPA | DSP30 | IL2
Journal Article
HLA, ISSN 2059-2302, 03/2016, Volume 87, Issue 3, pp. 160 - 164
Increasing evidence suggests that the rs6822844, within KIAA1109/TENR/IL2/IL21 gene cluster on 4q27, is strongly associated with rheumatoid arthritis (RA) in... 
susceptibility | rheumatoid arthritis | rs6822844 | interleukin (IL)2/IL21 | Susceptibility | Interleukin (IL)2/IL21 | Rheumatoid arthritis | Rs6822844 | INTERLEUKIN-2 | VARIANTS | CONFIRMATION | IMMUNOLOGY | PATHOLOGY | IL2 | REGION | FAMILY | CELL BIOLOGY | AUTOIMMUNE-DISEASES | IL2/IL21 | 4Q27
Journal Article
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 2012, Volume 13, Issue 2, pp. 621 - 623
Journal Article
Gastroenterology, ISSN 0016-5085, 2015, Volume 148, Issue 7, pp. 1383 - 1391.e6
Journal Article
Molecular Immunology, ISSN 0161-5890, 10/2019, Volume 114, pp. 81 - 87
Calcium is a key regulator of the T cell immune response. Depending on the spatial properties (nucleus versus cytoplasm) of the calcium signals generated after... 
T cell activation | Calcium | Gene expression | NFAT2 | IL2 | Anergy-related genes | Anopheles | Interleukins | Immunotherapy | Genes | Genetic transcription | T cells | Calcium-binding proteins
Journal Article
FRONTIERS IN PHARMACOLOGY, ISSN 1663-9812, 2012, Volume 3
Disease recurrence is frequent in high-risk neuroblastoma (NBL) patients even after multimodality aggressive treatment [a combination of chemotherapy, surgical... 
FcR | KIR | neuroblastoma | PHARMACOLOGY & PHARMACY | ADCC | IL2 | immunocytokine | mAb
Journal Article
Nephron, ISSN 1660-8151, 04/2018, Volume 139, Issue 1, pp. 30 - 38
Background: Despite advances in immunosuppression, acute allograft rejection remains one of the key factors affecting patient and graft survival in pediatric... 
Clinical Practice: Original Paper | Acute allograft rejection | Renal transplantation | Serum soluble IL2 receptor | UROLOGY & NEPHROLOGY | RENAL-ALLOGRAFT REJECTION | SIL-2R
Journal Article
Immunology Letters, ISSN 0165-2478, 2014, Volume 159, Issue 1, pp. 36 - 46
Highlights • rLaSota/IL2 has an antitumor potency but is not a pathogenic for man and poultry. • rLaSota/IL2 enhanced the anti-tumor effects and improved the... 
Allergy and Immunology | rLaSota/IL2 | Oncolytic therapy | NDV | Cancer therapy | Immunotherapy | IL2 | RLaSota/IL2 | GLIOBLASTOMA-MULTIFORME | TUMOR-CELLS | ONCOLYTIC VIRUS | MALIGNANT-MELANOMA | RECOMBINANT INTERLEUKIN-2 | IMMUNOLOGY | ANTITUMOR VACCINATION | HEPATOCELLULAR-CARCINOMA | IMMUNE-RESPONSES | IN-VIVO | PRIMARY LIVER-CANCER | Carcinoma, Hepatocellular - mortality | Immunotherapy - methods | Cell Proliferation | Humans | Liver Neoplasms, Experimental - mortality | Liver Neoplasms, Experimental - therapy | Liver Neoplasms, Experimental - immunology | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Cytotoxic - pathology | T-Lymphocytes, Regulatory - immunology | Interleukin-2 - immunology | Melanoma, Experimental - immunology | Skin Neoplasms - mortality | Carcinoma, Hepatocellular - immunology | Liver Neoplasms, Experimental - pathology | Adaptive Immunity | Skin Neoplasms - pathology | T-Lymphocytes, Cytotoxic - immunology | Gene Expression | Melanoma, Experimental - mortality | Skin Neoplasms - immunology | Skin Neoplasms - therapy | Melanoma, Experimental - therapy | Melanoma, Experimental - pathology | Tumor Burden | Interleukin-2 - genetics | Oncolytic Virotherapy - methods | Animals | Genetic Engineering | Newcastle disease virus - genetics | Carcinoma, Hepatocellular - pathology | Survival Analysis | Cell Line, Tumor | Immunologic Memory | Carcinoma, Hepatocellular - therapy | Mice | Interleukin-2 - biosynthesis | Virus diseases | Interleukins | Genetically modified organisms | Genetic engineering | Drug therapy | T cells | Cancer
Journal Article
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