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ARTHRITIS & RHEUMATOLOGY, ISSN 2326-5191, 10/2015, Volume 67, Issue 10, pp. 2742 - 2748
Objective. To independently replicate the top findings from 4 published genome-wide association studies (GWAS) of susceptibility genes in Behc, et's disease... 
IL10 | IL23R-IL12RB2 | SUSCEPTIBILITY LOCI | MHC | RHEUMATOLOGY | IDENTIFICATION | GENOME-WIDE ASSOCIATION
Journal Article
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, ISSN 0091-6749, 09/2011, Volume 128, Issue 3, pp. 655 - 664
Background: Behcet disease (BD) is a chronic systemic inflammatory disorder of unknown etiology. Objective: To determine the nature of T cells driving... 
vasculitis | INVOLVEMENT | INTERLEUKIN-21 | IMMUNOLOGY | T(H)1 | IL-21 | regulatory T cells | Behcet disease | autoimmunity | MULTIPLE-SCLEROSIS | ALLERGY | T(H)17 | IL23R-IL12RB2 | CENTRAL-NERVOUS-SYSTEM | CHOROID-PLEXUS | GENERATION | AUTOCRINE REGULATION | T-H-17 CELLS | GENOME-WIDE ASSOCIATION
Journal Article
Nature Genetics, ISSN 1061-4036, 02/2013, Volume 45, Issue 2, pp. 202 - 207
Journal Article
PLoS One, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, p. e31230
Background: Behcet's disease is known as a recurrent, multisystem inflammation and immune-related disease. Protein tyrosine phosphatase non-receptor 22... 
RHEUMATOID-ARTHRITIS | IL10 | JAPANESE POPULATION | MULTIDISCIPLINARY SCIENCES | IL23R-IL12RB2 | TYROSINE-PHOSPHATASE PTPN22 | AUTOIMMUNE-DISEASE | GENE POLYMORPHISMS | VARIANT | GENOME-WIDE ASSOCIATION | SILK ROAD | Genetic Predisposition to Disease | Eye Diseases - ethnology | Gene Frequency | Humans | Middle Aged | Protein Tyrosine Phosphatase, Non-Receptor Type 22 - genetics | Genotype | Male | Case-Control Studies | Polymorphism, Genetic | Behcet Syndrome - ethnology | Eye Diseases - genetics | Immune System | Polymorphism, Restriction Fragment Length | China | Adolescent | Polymerase Chain Reaction | Adult | Female | Aged | Behcet Syndrome - genetics | Tyrosine | Medical research | Phosphatases | Analysis | Genes | Medicine, Experimental | Disease susceptibility | Genetic aspects | Single nucleotide polymorphisms | T cells | Behcet's syndrome | Haplotypes | Multiple sclerosis | Populations | Laboratories | Pathogenesis | Lymphocytes T | Single-nucleotide polymorphism | Kinases | Phosphatase | Proteins | Lymphocytes | Rheumatology | Inflammation | Regression analysis | Disease control | Patients | Minority & ethnic groups | Crohns disease | Polymerase chain reaction | Hospitals | Restriction fragment length polymorphism | Gene frequency | Rheumatoid arthritis | Diabetes | Autoimmune diseases | Health risk assessment | Protein-tyrosine-phosphatase | Polymorphism
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 06/2014, Volume 111, Issue 24, pp. 8706 - 8707
Journal Article
Human Immunology, ISSN 0198-8859, 2016, Volume 77, Issue 12, pp. 1284 - 1290
Abstract Objectives Two genome-wide association studies (GWAS) have identified the IL-23 receptor- IL-12 receptor β2 ( IL23R - IL12RB2 ) as the susceptibility... 
Allergy and Immunology | Single nucleotide polymorphisms | Northern Chinese Han population | IL23R-IL12RB2 | Behcet’s disease
Journal Article
MODERN RHEUMATOLOGY, ISSN 1439-7595, 04/2012, Volume 22, Issue 2, pp. 298 - 302
A 47-year-old female patient with Beh double dagger et's disease had been treated with colchicine, prednisolone, cyclosporine A, and infliximab. Because she... 
RHEUMATOID-ARTHRITIS | Tocilizumab | Behcet's disease | RHEUMATOLOGY | CEREBROSPINAL-FLUID | INTERLEUKIN-6 | IL-6 | THERAPY | UVEORETINITIS | NEURO-BEHCETS SYNDROME | IL23R-IL12RB2 | GENERATION | T-CELLS | GENOME-WIDE ASSOCIATION
Journal Article
Arthritis Research and Therapy, ISSN 1478-6354, 06/2018, Volume 20, Issue 1, p. 124
Background: Low C-C chemokine receptor 1 (CCR1) and interleukin (IL)-10 expression is associated with risk of Behcet's disease (BD). The objective of the... 
CCR1 | Behçet's disease | GWAS | Macrophage polarization | IL-10 | CELLS | SUSCEPTIBILITY LOCI | Behcet's disease | RECEPTOR | INTERLEUKIN-10 | RHEUMATOLOGY | CHINESE HAN | IL23R-IL12RB2 | HEME OXYGENASE-1 | MUTATIONS | EXPRESSION | GENOME-WIDE ASSOCIATION
Journal Article
Journal Article
AUTOIMMUNITY REVIEWS, ISSN 1568-9972, 05/2015, Volume 14, Issue 5, pp. 370 - 375
Background and aims: Interferon alpha (IFN-alpha) is an effective treatment for patients with active Behcet disease (BD). Besides its antiviral property,... 
IL10 | Behcet's disease | CLASSIFICATION | IMMUNOLOGY | SLE | IL-10 | BETA | Systemic lupus erythematosus | I INTERFERONS | IL23R-IL12RB2 | T helper cells | REGULATORY T-CELLS | Interferon | GENOME-WIDE ASSOCIATION
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2018, Volume 13, Issue 9, p. e0204250
Background Behcets disease (BD) is a polygenic immune-mediated disorder characterized by a close association with the HLA-B*51 allele. The HLA region has a... 
MHC CLASS-I | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | POLYMORPHISMS | METAANALYSIS | GEOGRAPHICAL-PERSPECTIVES | INFLAMMATORY FACTOR-I | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | IL23R-IL12RB2 | LOCI | GENOME-WIDE ASSOCIATION
Journal Article
Journal of the American Academy of Dermatology, ISSN 0190-9622, 03/2018, Volume 78, Issue 3, pp. 464 - 470.e2
Many studies have shown a link between inflammation and cancer development. However, there are few studies regarding the correlation between Behçet disease... 
hazard ratio | cancer | Behçet disease | incidence | SUSCEPTIBILITY LOCI | ANKYLOSING-SPONDYLITIS | SILK ROAD | DERMATOLOGY | MALIGNANCY | INFLAMMATORY-BOWEL-DISEASE | Behcet disease | GASTRIC-CANCER | IL23R-IL12RB2 | SQUAMOUS-CELL CARCINOMA | MICA | GENOME-WIDE ASSOCIATION
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2013, Volume 110, Issue 20, pp. 8134 - 8139
Journal Article
Immunogenetics, ISSN 0093-7711, 6/2015, Volume 67, Issue 5, pp. 289 - 293
Despite that the association of Behçet’s disease (BD) with the HLA-B5 was first established in the 1970s, a number of recent genome-wide association studies... 
Human Genetics | Gene Function | Allergology | IL10 | Biomedicine | Immunology | Silk Route | IL23R-IL12RB2 | Iranian population | Behçet’s disease | HLA | Cell Biology
Journal Article
Nature Genetics, ISSN 1061-4036, 03/2017, Volume 49, Issue 3, pp. 438 - 443
Journal Article
Modern Rheumatology, ISSN 1439-7595, 03/2019, Volume 29, Issue 2, pp. 357 - 362
Objectives: This study aimed to identify patients with high-probability of ocular involvement of Behçet's disease (BD). Methods: The Japanese Ministry of... 
Behçet's syndrome | epidemiology | uveitis | surveys and questionnaires | Behcet's syndrome | IL10 | SERUM PROLACTIN LEVELS | IL23R-IL12RB2 | CLASS-I | PHENOTYPES | LOCI | RHEUMATOLOGY | GENOME-WIDE ASSOCIATION
Journal Article
CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY, ISSN 1080-0549, 12/2012, Volume 43, Issue 3, pp. 275 - 280
Beh double dagger et's syndrome (BS) is a disease of unknown etiology, and as such, there have been efforts to classify BS within the popular nosological... 
Behcet's syndrome | Phenotypic clusters | BEHCETS-SYNDROME PATIENTS | Autoinflammatory diseases | Crohn's disease | Seronegative spondarthritis | IMMUNOLOGY | ARTHRITIS | SKIN-LESIONS | ALLERGY | FAMILIES | DISEASE | IL23R-IL12RB2 | DOUBLE-BLIND | OCULAR MANIFESTATIONS | Autoimmune diseases | EPIDEMIOLOGY | GENOME-WIDE ASSOCIATION
Journal Article