2005, Topics in current chemistry, ISBN 3540225773, Volume 252., viii, 222
Book
Investigative Radiology, ISSN 0020-9996, 08/2015, Volume 50, Issue 8, pp. 473 - 480
OBJECTIVESTo prospectively compare in healthy rats the effect of multiple injections of macrocyclic (gadoterate meglumine) and linear (gadodiamide)...
signal intensity | magnetic resonance | gadoterate meglumine | deep cerebellar nuclei | cumulative doses | contrast agent | dentate nucleus | gadodiamide | gadolinium | DENTATE NUCLEUS | TRANSMETALATION | DEPOSITION | GLOBUS-PALLIDUS | CONSEQUENCES | BIODISTRIBUTION | MR-IMAGES | GADODIAMIDE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | NEPHROGENIC SYSTEMIC FIBROSIS | SIGNAL INTENSITY | Injections, Intravenous | Follow-Up Studies | Contrast Media - pharmacokinetics | Organometallic Compounds - pharmacokinetics | Rats | Cerebellar Nuclei - metabolism | Rats, Sprague-Dawley | Cerebellar Nuclei - drug effects | Magnetic Resonance Imaging | Animals | Contrast Media - administration & dosage | Meglumine - administration & dosage | Female | Gadolinium DTPA - pharmacokinetics | Gadolinium DTPA - administration & dosage | Meglumine - pharmacokinetics | Organometallic Compounds - administration & dosage | Original
signal intensity | magnetic resonance | gadoterate meglumine | deep cerebellar nuclei | cumulative doses | contrast agent | dentate nucleus | gadodiamide | gadolinium | DENTATE NUCLEUS | TRANSMETALATION | DEPOSITION | GLOBUS-PALLIDUS | CONSEQUENCES | BIODISTRIBUTION | MR-IMAGES | GADODIAMIDE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | NEPHROGENIC SYSTEMIC FIBROSIS | SIGNAL INTENSITY | Injections, Intravenous | Follow-Up Studies | Contrast Media - pharmacokinetics | Organometallic Compounds - pharmacokinetics | Rats | Cerebellar Nuclei - metabolism | Rats, Sprague-Dawley | Cerebellar Nuclei - drug effects | Magnetic Resonance Imaging | Animals | Contrast Media - administration & dosage | Meglumine - administration & dosage | Female | Gadolinium DTPA - pharmacokinetics | Gadolinium DTPA - administration & dosage | Meglumine - pharmacokinetics | Organometallic Compounds - administration & dosage | Original
Journal Article
1984, Handbook of experimental pharmacology, ISBN 9783540131076, Volume 73., xvi, 609
Book
1971, 1st ed., ISBN 0080161448, Volume section 76., 2 v.
Book
Radiology, ISSN 0033-8419, 10/2014, Volume 273, Issue 1, pp. 30 - 50
Computed tomography (CT) and magnetic resonance (MR) imaging play critical roles in the diagnosis and staging of hepatocellular carcinoma (HCC). The second...
MICROVASCULAR INVASION | SIGNAL-INTENSITY | PORTAL-VEIN THROMBOSIS | CHRONIC LIVER-DISEASE | TRIPLE-PHASE MDCT | ACID-ENHANCED MRI | GADOBENATE DIMEGLUMINE | CIRRHOTIC LIVER | APPARENT DIFFUSION-COEFFICIENT | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | GADOXETATE DISODIUM | Liver - pathology | Contrast Media | Neoplasm Invasiveness | Humans | Liver - diagnostic imaging | Carcinoma, Hepatocellular - pathology | Magnetic Resonance Imaging - methods | Tomography, X-Ray Computed - methods | Liver Neoplasms - pathology | Neoplasm Staging | Liver Neoplasms - diagnostic imaging | Carcinoma, Hepatocellular - diagnostic imaging | Reviews and
MICROVASCULAR INVASION | SIGNAL-INTENSITY | PORTAL-VEIN THROMBOSIS | CHRONIC LIVER-DISEASE | TRIPLE-PHASE MDCT | ACID-ENHANCED MRI | GADOBENATE DIMEGLUMINE | CIRRHOTIC LIVER | APPARENT DIFFUSION-COEFFICIENT | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | GADOXETATE DISODIUM | Liver - pathology | Contrast Media | Neoplasm Invasiveness | Humans | Liver - diagnostic imaging | Carcinoma, Hepatocellular - pathology | Magnetic Resonance Imaging - methods | Tomography, X-Ray Computed - methods | Liver Neoplasms - pathology | Neoplasm Staging | Liver Neoplasms - diagnostic imaging | Carcinoma, Hepatocellular - diagnostic imaging | Reviews and
Journal Article
Investigative Radiology, ISSN 0020-9996, 2016, Volume 51, Issue 2, pp. 83 - 89
Objectives: In this prospective preclinical study, we evaluated T1-weighted signal intensity in the deep cerebellar nuclei (CN) and globus pallidus (GP) up to...
Animal experiment | Pons | MRI | Contrast agent | GBCA | Gadolinium | Cerebrospinal fluid | Retention | STABILITY | GLOBUS-PALLIDUS | INTENSITY | contrast agent | animal experiment | pons | DENTATE NUCLEUS | DIMEGLUMINE | cerebrospinal fluid | ENHANCEMENT | GADOTERIDOL | ADMINISTRATIONS | GADODIAMIDE | GADOPENTETATE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | retention | gadolinium | Gadolinium - administration & dosage | Reproducibility of Results | Brain - anatomy & histology | Drug Administration Schedule | Rats, Wistar | Rats | Male | Dose-Response Relationship, Drug | Animals | Contrast Media - administration & dosage | Sensitivity and Specificity | Image Enhancement - methods | Macrocyclic Compounds - administration & dosage | Diffusion Magnetic Resonance Imaging - methods | Original
Animal experiment | Pons | MRI | Contrast agent | GBCA | Gadolinium | Cerebrospinal fluid | Retention | STABILITY | GLOBUS-PALLIDUS | INTENSITY | contrast agent | animal experiment | pons | DENTATE NUCLEUS | DIMEGLUMINE | cerebrospinal fluid | ENHANCEMENT | GADOTERIDOL | ADMINISTRATIONS | GADODIAMIDE | GADOPENTETATE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | retention | gadolinium | Gadolinium - administration & dosage | Reproducibility of Results | Brain - anatomy & histology | Drug Administration Schedule | Rats, Wistar | Rats | Male | Dose-Response Relationship, Drug | Animals | Contrast Media - administration & dosage | Sensitivity and Specificity | Image Enhancement - methods | Macrocyclic Compounds - administration & dosage | Diffusion Magnetic Resonance Imaging - methods | Original
Journal Article
Advanced Materials, ISSN 0935-9648, 05/2013, Volume 25, Issue 19, pp. 2641 - 2660
Computed tomography (CT) is one of the most widely used clinical imaging modalities. In order to increase the sensitivity of CT, small iodinated compounds are...
computed tomography | nanoparticle | in vivo imaging | contrast agent | X‐ray | X-ray | PHYSICS, CONDENSED MATTER | TARGETED GOLD NANOPARTICLES | PHYSICS, APPLIED | DRUG-DELIVERY | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | LARGE-SCALE SYNTHESIS | CHEMISTRY, MULTIDISCIPLINARY | UP-CONVERSION NANOPHOSPHORS | MULTIFUNCTIONAL MAGNETIC NANOPARTICLES | IN-VIVO | BIOMEDICAL APPLICATIONS | RAY-COMPUTED-TOMOGRAPHY | BISMUTH SULFIDE NANOPARTICLES | BLOOD-POOL | Contrast Media - chemical synthesis | Nanomedicine - trends | Nanoparticles - chemistry | Nanoparticles - ultrastructure | Tomography, X-Ray Computed - trends | CT imaging | Contrast media | Contrast agents | Nanocomposites | Lanthanides | Imaging | X-rays | Nanomaterials | Nanostructure | Circulation
computed tomography | nanoparticle | in vivo imaging | contrast agent | X‐ray | X-ray | PHYSICS, CONDENSED MATTER | TARGETED GOLD NANOPARTICLES | PHYSICS, APPLIED | DRUG-DELIVERY | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | LARGE-SCALE SYNTHESIS | CHEMISTRY, MULTIDISCIPLINARY | UP-CONVERSION NANOPHOSPHORS | MULTIFUNCTIONAL MAGNETIC NANOPARTICLES | IN-VIVO | BIOMEDICAL APPLICATIONS | RAY-COMPUTED-TOMOGRAPHY | BISMUTH SULFIDE NANOPARTICLES | BLOOD-POOL | Contrast Media - chemical synthesis | Nanomedicine - trends | Nanoparticles - chemistry | Nanoparticles - ultrastructure | Tomography, X-Ray Computed - trends | CT imaging | Contrast media | Contrast agents | Nanocomposites | Lanthanides | Imaging | X-rays | Nanomaterials | Nanostructure | Circulation
Journal Article
Chemical Society reviews, ISSN 0306-0012, 07/2015, Volume 44, Issue 14, pp. 4484 - 4486
Journal Article
Chemical Reviews, ISSN 0009-2665, 03/2013, Volume 113, Issue 3, pp. 1641 - 1666
ACTIVATION-RELATED PSEUDOALLERGY | NONINVASIVE QUANTITATIVE MEASUREMENT | XENON VENTILATION CT | DUAL-ENERGY TECHNIQUE | ARTICULAR-CARTILAGE | IN-VIVO | LARGE-SCALE SYNTHESIS | TISSUE BLOOD-FLOW | CHEMISTRY, MULTIDISCIPLINARY | COATED GOLD NANOPARTICLES | NEPHROGENIC SYSTEMIC FIBROSIS | Nanoparticles | Gold | Iodine - chemistry | Liposomes - chemistry | Lanthanoid Series Elements - chemistry | Humans | Nanocapsules | Xenon | Tomography, X-Ray Computed - methods | Contrast Media - chemistry | CT imaging | Usage | Analysis | Electromagnetic waves | Electric waves | Electromagnetic radiation | Bismuth | Research | Chemical properties
Journal Article
10.
Full Text
[18 F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2013, Volume 9, Issue 6, pp. 666 - 676
Abstract Objective We wished to develop a highly selective positron emission tomography (PET) imaging agent targeting PHF-tau in human Alzheimer's disease (AD)...
Neurology | Autoradiography | Tau | Alzheimer’s disease | [18F]T807 | Amyloid β | Imaging | F]T807 | Alzheimer's disease | NEUROFIBRILLARY TANGLES | PROTEIN | A-BETA-42 | PET TRACER | PLAQUES | CEREBROSPINAL-FLUID | PITTSBURGH COMPOUND-B | CLINICAL NEUROLOGY | BIOMARKERS | [F-18]T807 | Amyloid beta | AMYLOID-BETA | AGGREGATION | Brain - diagnostic imaging | Protein Binding - genetics | Humans | Middle Aged | Male | Mice, Transgenic | Positron-Emission Tomography | Case-Control Studies | tau Proteins - chemistry | Alzheimer Disease - diagnosis | Tissue Distribution | Animals | tau Proteins - genetics | Protein Binding - drug effects | Amyloid beta-Peptides - metabolism | Aged, 80 and over | Brain - pathology | Female | Aged | Mice | Fluorine Radioisotopes | tau Proteins - drug effects | PET imaging | Drug therapy | Amyloid beta-protein
Neurology | Autoradiography | Tau | Alzheimer’s disease | [18F]T807 | Amyloid β | Imaging | F]T807 | Alzheimer's disease | NEUROFIBRILLARY TANGLES | PROTEIN | A-BETA-42 | PET TRACER | PLAQUES | CEREBROSPINAL-FLUID | PITTSBURGH COMPOUND-B | CLINICAL NEUROLOGY | BIOMARKERS | [F-18]T807 | Amyloid beta | AMYLOID-BETA | AGGREGATION | Brain - diagnostic imaging | Protein Binding - genetics | Humans | Middle Aged | Male | Mice, Transgenic | Positron-Emission Tomography | Case-Control Studies | tau Proteins - chemistry | Alzheimer Disease - diagnosis | Tissue Distribution | Animals | tau Proteins - genetics | Protein Binding - drug effects | Amyloid beta-Peptides - metabolism | Aged, 80 and over | Brain - pathology | Female | Aged | Mice | Fluorine Radioisotopes | tau Proteins - drug effects | PET imaging | Drug therapy | Amyloid beta-protein
Journal Article
Hypertension, ISSN 0194-911X, 02/2017, Volume 69, Issue 2, pp. 243 - 248
Higher levels of serum uric acid are independently associated with endothelial dysfunction, a mechanism for incident hypertension. Overweight/obese individuals...
probenecid | blood pressure | allopurinol | uric acid | HYPERURICEMIA | GLUCOSE | PERIPHERAL VASCULAR DISEASE | FILTRATION-RATE | VASODILATION | DYSFUNCTION | Overweight - complications | Follow-Up Studies | Humans | Endothelium, Vascular - drug effects | Hypertension - drug therapy | Male | Dose-Response Relationship, Drug | Hypertension - blood | Brachial Artery - diagnostic imaging | Time Factors | Adult | Brachial Artery - physiopathology | Female | Brachial Artery - drug effects | Uric Acid - blood | Vasodilation - physiology | Double-Blind Method | Ultrasonography, Doppler | Uricosuric Agents - administration & dosage | Endothelium, Vascular - physiopathology | Probenecid - administration & dosage | Treatment Outcome | Hypertension - physiopathology | Gout Suppressants - administration & dosage | Allopurinol - administration & dosage | endothelial function | randomized trial
probenecid | blood pressure | allopurinol | uric acid | HYPERURICEMIA | GLUCOSE | PERIPHERAL VASCULAR DISEASE | FILTRATION-RATE | VASODILATION | DYSFUNCTION | Overweight - complications | Follow-Up Studies | Humans | Endothelium, Vascular - drug effects | Hypertension - drug therapy | Male | Dose-Response Relationship, Drug | Hypertension - blood | Brachial Artery - diagnostic imaging | Time Factors | Adult | Brachial Artery - physiopathology | Female | Brachial Artery - drug effects | Uric Acid - blood | Vasodilation - physiology | Double-Blind Method | Ultrasonography, Doppler | Uricosuric Agents - administration & dosage | Endothelium, Vascular - physiopathology | Probenecid - administration & dosage | Treatment Outcome | Hypertension - physiopathology | Gout Suppressants - administration & dosage | Allopurinol - administration & dosage | endothelial function | randomized trial
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 08/2016, Volume 22, Issue 34, pp. 12122 - 12129
Recently, we demonstrated the potential of a [18F]‐trimethylammonium BODIPY dye for cardiac imaging. This is the first example of the use of the [18F]‐ammonium...
radiopharmaceuticals | BODIPY | fluorine-18 | dual-modality imaging | medicinal chemistry | PET AGENTS | IN-VIVO STABILITY | CHEMISTRY, MULTIDISCIPLINARY | ONE-STEP | FLUORESCENT | RADIOSYNTHESIS | F-18-LABELED RHODAMINE-B | EXCHANGE | F-18-FLUOROBENZYL TRIPHENYL PHOSPHONIUM | CATION | TRIPHENYLPHOSPHONIUM | PET imaging | Fluorides | Tomography | Dyes | Medical imaging | Ammonium | Emission analysis | Positron emission | Pharmacology | Emissions | Perfusion | Imaging | Myocardium | Probes | Heart diseases | Positron emission tomography | Tracers | Uptakes | Nitrogen
radiopharmaceuticals | BODIPY | fluorine-18 | dual-modality imaging | medicinal chemistry | PET AGENTS | IN-VIVO STABILITY | CHEMISTRY, MULTIDISCIPLINARY | ONE-STEP | FLUORESCENT | RADIOSYNTHESIS | F-18-LABELED RHODAMINE-B | EXCHANGE | F-18-FLUOROBENZYL TRIPHENYL PHOSPHONIUM | CATION | TRIPHENYLPHOSPHONIUM | PET imaging | Fluorides | Tomography | Dyes | Medical imaging | Ammonium | Emission analysis | Positron emission | Pharmacology | Emissions | Perfusion | Imaging | Myocardium | Probes | Heart diseases | Positron emission tomography | Tracers | Uptakes | Nitrogen
Journal Article