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Circulation, ISSN 0009-7322, 03/2013, Volume 127, Issue 10, pp. 1128 - 1138
Journal Article
Annals of Surgery, ISSN 0003-4932, 09/2013, Volume 258, Issue 3, pp. 422 - 428
Journal Article
Recent Results in Cancer Research, ISSN 0080-0015, 2018, Volume 212, pp. 1 - 27
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 09/2007, Volume 102, Issue 6, pp. 1749 - 1757
Imatinib, a protein tyrosine kinase inhibitor, may prevent the growth of glioblastoma cells. Unfortunately, its brain distribution is restricted by... 
CGP74588 | mouse | p‐glycoprotein | imatinib | blood–brain barrier | breast cancer resistance protein | Imatinib | Blood-brain barrier | Mouse | Breast cancer resistance protein | p-glycoproteinz | blood-brain barrier | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | p-glycoprotein | C-KIT | DRUG-RESISTANCE | DEFICIENT MICE | GF120918 | NEUROSCIENCES | REVERSAL | IN-VITRO | PHARMACOKINETICS | TYROSINE KINASE INHIBITOR | MULTIDRUG-RESISTANCE | Male | Piperazines - metabolism | Cyclosporins - pharmacology | Pyrimidines - metabolism | Quinolines - pharmacology | Antineoplastic Agents - metabolism | Brain - metabolism | Dose-Response Relationship, Drug | Brain - blood supply | ATP Binding Cassette Transporter, Subfamily B, Member 1 | ATP-Binding Cassette Transporters - genetics | Biological Transport, Active - physiology | ATP-Binding Cassette Transporters - metabolism | Dibenzocycloheptenes - pharmacology | ATP Binding Cassette Transporter, Subfamily B - genetics | Piperazines - pharmacokinetics | Immunosuppressive Agents - pharmacology | ATP Binding Cassette Transporter, Subfamily G, Member 2 | Tetrahydroisoquinolines - pharmacology | Biological Transport, Active - drug effects | Enzyme Inhibitors - pharmacology | Blood-Brain Barrier - drug effects | Imatinib Mesylate | ATP Binding Cassette Transporter, Subfamily B - metabolism | Blood-Brain Barrier - metabolism | Mice, Knockout | Brain - drug effects | Animals | ATP Binding Cassette Transporter, Subfamily B - antagonists & inhibitors | Acridines - pharmacology | Pyrimidines - pharmacokinetics | Mice | Benzamides | ATP-Binding Cassette Transporters - antagonists & inhibitors | Physiological aspects | Breast cancer | Proteins | Neurosciences | Inhibitor drugs | Rodents | Biochemistry | Glycoproteins | Index Medicus
Journal Article
The Journal of Immunology, ISSN 0022-1767, 11/2008, Volume 181, Issue 10, pp. 6955 - 6963
Journal Article
Cancer, ISSN 0008-543X, 11/2004, Volume 101, Issue 9, pp. 2086 - 2097
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 08/2006, Volume 12, Issue 8, pp. 908 - 916
Imatinib mesylate (Gleevec) is a small-molecule inhibitor of the fusion protein Bcr-Abl, the causal agent in chronic myelogenous leukemia. Here we report ten... 
CHRONIC MYELOGENOUS LEUKEMIA | ADJUVANT CHEMOTHERAPY | MEDICINE, RESEARCH & EXPERIMENTAL | C-ABL | ABL TYROSINE KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-TERMINAL KINASE | NEURONAL CELL-DEATH | ENDOPLASMIC-RETICULUM STRESS | HER2-POSITIVE BREAST-CANCER | CHRONIC MYELOID-LEUKEMIA | CELL BIOLOGY | UNFOLDED PROTEIN RESPONSE | Mitochondria, Heart - ultrastructure | Piperazines - administration & dosage | Calcium - metabolism | Mitochondria, Heart - pathology | Sarcoplasmic Reticulum - drug effects | Humans | Piperazines - toxicity | Antineoplastic Agents - administration & dosage | Mitochondria, Heart - drug effects | Ventricular Dysfunction, Left - chemically induced | Antineoplastic Agents - toxicity | Dose-Response Relationship, Drug | Mitochondrial Membranes - drug effects | Pyrimidines - toxicity | Time Factors | Adenosine Triphosphatases - analysis | Antineoplastic Agents - adverse effects | Sarcoplasmic Reticulum - ultrastructure | Antineoplastic Agents - pharmacology | Cell Death - drug effects | Membrane Potentials - drug effects | Severity of Illness Index | Cytochromes c - secretion | Echocardiography | Pyrimidines - administration & dosage | Mice, Inbred C57BL | Cells, Cultured | Injections, Intraperitoneal | Adenosine Triphosphatases - metabolism | Heart Failure - pathology | Pyrimidines - pharmacology | Imatinib Mesylate | Piperazines - adverse effects | Piperazines - pharmacology | Ventricular Dysfunction, Left - physiopathology | Myocytes, Cardiac - pathology | Animals | Myocytes, Cardiac - drug effects | Cell Membrane Permeability - drug effects | Pyrimidines - adverse effects | Sarcoplasmic Reticulum - pathology | Mice | Benzamides | Myocytes, Cardiac - ultrastructure | Heart Failure - chemically induced | Heart failure | Chemotherapy | Side effects | Inhibitor drugs | Toxicity | Cardiovascular disease | Cancer | Index Medicus
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2011, Volume 70, Issue 6, pp. 1003 - 1009
Journal Article
Cancer, ISSN 0008-543X, 08/2008, Volume 113, Issue 4, pp. 723 - 732
Journal Article
Journal Article