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glycosidase inhibition (28) 28
iminosugar click clusters (28) 28
chemistry, organic (26) 26
iminosugars (24) 24
pharmacological chaperones (24) 24
index medicus (23) 23
multivalency (18) 18
inhibitors (17) 17
binding (14) 14
enzymes (13) 13
chemistry, multidisciplinary (12) 12
glycosidases (12) 12
biochemistry & molecular biology (11) 11
affinity (10) 10
gaucher-disease (10) 10
enzyme inhibitors - chemistry (9) 9
glycosidase (9) 9
humans (9) 9
inhibition (9) 9
inhibitor (9) 9
ligands (9) 9
carbohydrates (8) 8
chemistry, medicinal (8) 8
click clusters (8) 8
cyclodextrins (8) 8
enzyme inhibitors - pharmacology (8) 8
glycoside hydrolases - antagonists & inhibitors (8) 8
imino sugars - pharmacology (8) 8
inhibitors:material (8) 8
lysosomal storage disorders (8) 8
carbohydrate-processing enzymes (7) 7
chemistry (7) 7
concanavalin-a (7) 7
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lectin (7) 7
lectins (7) 7
multivalent iminosugars (7) 7
organic chemistry (7) 7
animals (6) 6
click chemistry (6) 6
glycoside hydrolases - metabolism (6) 6
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multivalent (6) 6
structure-activity relationship (6) 6
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carbohydrate-protein interactions (5) 5
chemical sciences (5) 5
cycloaddition (5) 5
enzym (5) 5
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glycoclusters (5) 5
1,3-dipolar cycloadditions (4) 4
acid beta-glucosidase (4) 4
dose-response relationship, drug (4) 4
enzyme replacement therapy (4) 4
enzyme-inhibition (4) 4
enzyminhibition (4) 4
fulleren (4) 4
fullerene (4) 4
gaucher disease (4) 4
glucocerebrosidase (4) 4
glycoconjugates (4) 4
gold nanoparticles (4) 4
hyacinthacine a (4) 4
influenza-virus neuraminidase (4) 4
life sciences (4) 4
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molecular structure (4) 4
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proteins (4) 4
7-deoxycasuarine (3) 3
alpha-l-fucosidase (3) 3
architectures (3) 3
azasugars (3) 3
balls (3) 3
beta-cyclodextrin (3) 3
beta-cyclodextrins - chemistry (3) 3
beta-galactosidase (3) 3
calixarenes (3) 3
conjugates (3) 3
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Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 10/2016, Volume 2016, Issue 30, pp. 5102 - 5116
Although the preparation of anomeric glycosylsulfonyl fluoride was unsuccessful, a tetra‐O‐acetylated C‐glucosylpropanesulfonyl fluoride was synthesized... 
Glycocluster | Iminosugars | Glycoconjugates | Calixarenes | Sulfonamides | Synthetic methods | Sulfonyl fluoride | SULFONYL FLUORIDES | GLYCOCLUSTERS | CHEMISTRY, ORGANIC | C-GLYCOSIDES | MEDICINAL CHEMISTRY | THIOLS | O-GLYCOSYL | CHLORIDES | INHIBITORS | GLYCOMIMETICS
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2019, Volume 17, Issue 23, pp. 5801 - 5817
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 06/2019, Volume 62, Issue 12, pp. 5832 - 5843
alpha-Mannosidosis (AM) results from deficient lysosomal a-mannosidase (LAMAN) activity and subsequent substrate accumulation in the lysosome, leading to... 
IMINOSUGAR CLICK CLUSTERS | LECTIN RECOGNITION | CHEMISTRY, MEDICINAL | DISEASES | THERAPY | GLYCOSIDASE INHIBITION | CYCLODEXTRIN | MULTIVALENT IMINOSUGARS | CHEMISTRY | BINDING | GAUCHER
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2018, Volume 16, Issue 44, pp. 8604 - 8612
Gold glyconanoparticles (Au GNPs) decorated with the natural iminosugar DAB-1 at different densities are reported. These new multivalent iminosugar... 
Journal Article
ORGANIC & BIOMOLECULAR CHEMISTRY, ISSN 1477-0520, 11/2018, Volume 16, Issue 44, pp. 8604 - 8612
Gold glyconanoparticles (Au GNPs) decorated with the natural iminosugar DAB-1 at different densities are reported. These new multivalent iminosugar... 
IMINOSUGAR CLICK CLUSTERS | GOLD NANOPARTICLES | ENZYME ASSAY | GLYCOSIDASE INHIBITION | HYACINTHACINE A | PHARMACOLOGICAL CHAPERONES | SOLID-PHASE | CHEMISTRY, ORGANIC | GLYCONANOPARTICLES | MULTIVALENT | BINDING
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 9/2015, Volume 13, Issue 39, pp. 9894 - 996
Multivalent nanoconstructs, extensively used for enhancing the recognition of biomolecular targets, have been recently exploited for enzyme inhibition showing... 
IMINOSUGAR CLICK CLUSTERS | GOLD NANOPARTICLES | BEARING 4-GUANIDINO-NEU5AC2EN DERIVATIVES | GLYCOSIDASE INHIBITION | CHEMISTRY, ORGANIC | INFLUENZA-VIRUS NEURAMINIDASE | CHEMICAL-BIOLOGY | DYNAMIC COMBINATORIAL CHEMISTRY | CARBOHYDRATE-PROCESSING ENZYMES | DNA COMPLEXATION | AMPHIPHILIC DENDRIMERS
Journal Article