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Molecular Cell, ISSN 1097-2765, 11/2011, Volume 44, Issue 3, pp. 348 - 360
Journal Article
Science, ISSN 0036-8075, 8/2011, Volume 333, Issue 6046, pp. 1161 - 1163
MED23 is a subunit of the Mediator complex, a key regulator of protein-coding gene expression. Here, we report a missense mutation (p. R617Q) in MED23 that... 
Chromatin | Intellectual disability | Transcriptional activation | rev genes | Immediate early genes | Genes | REPORTS | Cell lines | Fibroblasts | Gene expression | Genetic mutation | RECRUITMENT | ACTIVATION | JUN | MECHANISM | PATHWAY | TFIIH | MULTIDISCIPLINARY SCIENCES | CHROMATIN MODIFICATION | PREINITIATION COMPLEX | TRANSCRIPTIONAL REGULATION | MEDIATOR COMPLEX | Promoter Regions, Genetic | Transcription Factor 4 | Humans | Transcriptional Activation | Cells, Cultured | Gene Expression Regulation | Male | Mediator Complex - genetics | Mutation, Missense | Intellectual Disability - genetics | Transcription Factors - metabolism | Chromatin Immunoprecipitation | Pedigree | ets-Domain Protein Elk-1 - metabolism | Genes, fos | Early Growth Response Protein 1 - genetics | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Female | Genes, Immediate-Early | Histones - metabolism | Genes, jun | Intelligence levels | Gene mutations | Intellect | Physiological aspects | DNA binding proteins | Research | Proteins | Mutagenesis | Cognition & reasoning | Molecular biology | Neurological disorders | ets-Domain Protein Elk-1 | Life Sciences | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors | Early Growth Response Protein 1 | Histones | Genetics | Transcription Factors | Mediator Complex | Intellectual Disability | Human genetics
Journal Article
eLife, ISSN 2050-084X, 2015, Volume 4, Issue 4, pp. e03971 - e03971
Eukaryotic cells rapidly reduce protein synthesis in response to various stress conditions. This can be achieved by the phosphorylation-mediated inactivation... 
Integrated stress response (ISR) | Upstream open reading frame (uORF) | evolutionary biology | biochemistry | 5' leader translation | genomics | Bicistronic mRNA | 5′ leader translation | human | Eukaryotic initiation factor 2 (eIF2) | Ribosome profiling | SCANNING MECHANISM | ALPHA-SUBUNIT | PHOSPHORYLATION | bicistronic mRNA | eukaryotic initiation factor 2 (eIF2) | INITIATION-FACTOR 2 | MESSENGER-RNA STABILITY | PROTEIN-SYNTHESIS | UNTRANSLATED REGION | CHOP TRANSLATION | ribosome profiling | IN-VIVO | DEPHOSPHORYLATION | BIOLOGY | integrated stress response (ISR) | upstream open reading frame (uORF) | Arsenites - pharmacology | Mutagenesis, Site-Directed | Gene Expression Regulation - genetics | Humans | RNA, Messenger - genetics | Oxidative Stress - genetics | Ribosomes - metabolism | Open Reading Frames - genetics | RNA, Messenger - metabolism | Sodium Compounds - pharmacology | Gene Expression Regulation - drug effects | Immediate-Early Proteins - metabolism | Protein Phosphatase 1 - metabolism | Immediate-Early Proteins - genetics | HEK293 Cells | Protein Phosphatase 1 - genetics | Ribosomes - drug effects | Eukaryotic Initiation Factor-2 - metabolism | Protein Biosynthesis - drug effects | Protein Biosynthesis - genetics | Oxidative Stress - drug effects | Repressor Proteins - metabolism | Leadership | Translation | Phosphorylation | Translation initiation | Protein biosynthesis | Phylogeny | Gene expression | Kinases | Proteins | Gene silencing | Sodium | Mutagenesis | Protein synthesis | Protein folding | Open reading frames | Sodium arsenite | Arsenite | Index Medicus
Journal Article
2006, ISBN 0387336036, x, 293
Provides a compilation of the most up-to-date literature on the topic of immediate early genes (IEGs), by the leading authors of the field of molecular... 
Neurogenetics | Central nervous system | Clinical & internal medicine | Neurosciences | Molecular Medicine | Biomedicine | Neurobiology
Book
Journal Article
Molecular Biology Reports, ISSN 0301-4851, 6/2012, Volume 39, Issue 6, pp. 6781 - 6789
Journal Article